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Aurodox

Antibiotic obtained from a Streptomyces variant considered as possibly effective against Streptococcus pyogenes infections. It may promote growth in poultry.

Also Known As:

Antibiotic X 5108; Goldinomycin; N-Methylkirromycin; X-5108; X5108; N Methylkirromycin; X 5108; Goldinodox; Mocimycin, 1-methyl-

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 58
- Hydrocarbons: 412
  - Acyclic Hydrocarbons
    - Alkenes: 45
      - Polyenes: 90
        Aurodox: 1
        A 83016F
        SB 22484

Experts

1.	Kimura, Kyota: 1 article (02/2011)
2.	Nagai, Takeshi: 1 article (02/2011)
3.	Omura, Satoshi: 1 article (02/2011)
4.	Takahashi, Yoko: 1 article (02/2011)
5.	Abe, Akio: 1 article (02/2011)
6.	Matsumoto, Atsuko: 1 article (02/2011)
7.	Shiomi, Kazuro: 1 article (02/2011)
8.	Iwatsuki, Masato: 1 article (02/2011)

Related Diseases

1.	Infection 02/01/2011 - "Furthermore, an in vivo infection study using mice clearly indicated that the administration of aurodox allowed the mice to survive a lethal dose of Citrobactor rodentium, a model bacterium for human pathogens such as EPEC. "
2.	Hemolysis 02/01/2011 - "Aurodox strongly inhibited T3SS-mediated hemolysis with an IC(50) value of 1.5 μg ml(-1) without affecting bacterial growth in liquid media. " 02/01/2011 - "We identified a linear polyketide compound, aurodox, as a specific T3SS inhibitor from the culture broth of Streptomyces sp. using a screening system for the T3SS-mediated hemolysis of enteropathogenic Escherichia coli (EPEC) established by our group. "