Anti-Infective Agents (Microbicides)

01/01/2015 - "Most antimicrobial agents recommended for treatment of V. vulnificus and V. cholerae non-O1/non-O139 infections were found to be effective in vitro. "
10/01/2012 - "The identification of Clostridium in specimens from an osteoarticular infection indicates a need for extremely extensive and aggressive surgical resection, as spore resistance may impair the in vivo efficacy of antimicrobial agents. "
12/01/2008 - "Bacteria causing infections in swine have in several cases acquired resistance to a number of the agents most commonly used for treatment, making it difficult to predict the efficacy of different antimicrobial agents without prior susceptibility testing. "
05/01/2001 - "However, increasing rates of antimicrobial resistance may dramatically reduce the efficacy of the antimicrobial agents used to control Pasteurella and Mannheimia infections. "
01/01/2001 - "Although Streptococcus agalactiae remains highly susceptible to antimicrobial agents effective against gram-positive cocci, the changing epidemiology and potentially invasive nature of these infections should have clinicians alert to the possibility of infection caused by group B streptococci."

12/01/1995 - "The factors important in the success of the program included improved recognition of the signs of childhood pneumonia by parents, earlier presentation of children with these signs to health care facilities, availability of antimicrobial agents at the primary health care level, and rational decisions by health care workers about the use of these agents."
06/01/1984 - "A 13-year-old boy with pneumonia recovered in spite of therapy with antimicrobial agents not proven to be effective against the legionellae. "
01/01/2010 - "Combination therapy with two antimicrobial agents is superior to monotherapy in severe community-acquired pneumonia, and recent data suggest that addition of a macrolide as the second antibiotic might be superior to other combinations. "
01/01/2010 - "Experimental models of pneumonia have played a crucial role for testing the efficacy of antimicrobial agents as well as for gaining a better understanding of the disease pathogenesis. "
11/01/2010 - "To be an effective treatment for MRSA pneumonia, antimicrobial agents must have activity against antimicrobial-resistant S. "

04/07/2001 - "[High sensitivity of Escherichia coli to antimicrobial agents used for first-line treatment of urinary tract infections; results of an examination of feces of healthy subjects in Friesland]."
09/01/1983 - "Overall clinical assessment by the committee according to the "Criteria for Evaluation of Clinical Efficacy of Antimicrobial Agents on Urinary Tract Infection" patients evaluated as better than "good" were 64 of 105 (61.0%) for CXD and 75 of 115 (65.2%) for CEX. "
01/01/1990 - "In women a single dose of any of several antimicrobial agents is as effective as a course of treatment for uncomplicated urinary tract infections caused by Escherichia coli. "
06/01/2000 - "Criteria for evaluation of clinical efficacy of antimicrobial agents on urinary tract infection. "
06/01/1997 - "Criteria for evaluation of clinical efficacy of antimicrobial agents on urinary tract infection."

01/01/2012 - "We aimed to compare the clinical efficacy of the two day regimen of prophylactic antimicrobial agents with the five day regimen in simple traumatic but highly contaminated wounds. "
07/01/2007 - "These data show that the DRDC puffs and meshes are effective in delivering certain medications, such as antimicrobial agents, to the wound bed, suggesting considerable value of this material for treating wounds, especially those with irregular shapes, contours, and depths."
09/16/2003 - "The studies reported here have been undertaken to assess the potential use of isothermal microcalorimetry in studying the antimicrobial efficacy of wound dressings that contain antimicrobial agents. "
11/01/2014 - "Increased tolerance of biofilms to antimicrobial agents explains the limited efficacy of antimicrobial agents in chronic wounds and illustrates the need to develop new management strategies. "
08/01/1994 - "Forty-three medical centers participated in a national (United States) surveillance study of parenteral antimicrobial agents as empiric therapy of pathogens isolated from blood, skin wounds, respiratory tract, and urine (> 8500 strains, 200 per laboratory). "

03/18/2003 - "Despite the advances in supportive care and the availability of potent antimicrobial agents, mortality from sepsis, a leading cause of death in intensive care units, has not improved. "
09/01/2014 - "Barriers to the effective treatment of sepsis: antimicrobial agents, sepsis definitions, and host-directed therapies."
03/01/1988 - "With further characterization of this model we plan to use it as an in vivo assay to compare the efficacy of different antimicrobial agents in intraabdominal sepsis."
06/01/2010 - "This review describes recent pharmacokinetic and/or pharmacodynamic studies of antimicrobial agents used for treatment of neonatal sepsis. "
11/16/2001 - "We made a prospective, observational, descriptive study of 100 patients who needed neurosurgical operations and were given antimicrobial agents to prevent sepsis. "