Anthocyanins (Anthocyanin)

A group of FLAVONOIDS derived from FLAVONOLS, which lack the ketone oxygen at the 4-position. They are glycosylated versions of cyanidin, pelargonidin or delphinidin. The conjugated bonds result in blue, red, and purple colors in flowers of plants.

Also Known As:

Networked: 612 relevant articles (58 outcomes, 133 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Ling, Wenhua: 16 articles (07/2015 - 08/2006)
2.	Xia, Min: 14 articles (04/2015 - 08/2006)
3.	Shin, Sung Chul: 14 articles (03/2015 - 02/2006)
4.	Lee, Won Sup: 11 articles (03/2015 - 04/2009)
5.	Guo, Honghui: 10 articles (07/2015 - 03/2007)
6.	Choi, Yung Hyun: 9 articles (03/2015 - 04/2009)
7.	Nair, Muraleedharan G: 9 articles (08/2011 - 01/2003)
8.	Kim, Hye Jung: 8 articles (03/2015 - 02/2006)
9.	Gescher, Andreas J: 8 articles (06/2011 - 09/2006)
10.	Cassidy, Aedín: 7 articles (06/2015 - 12/2009)

Related Diseases

1.	Neoplasms (Cancer) 12/01/2015 - "Considering the evidence of bioactive compounds, such as anthocyanins, against cancers, there is a critical need to study anticancer activity of PP, a global food crop, against colon CSCs. " 06/01/2015 - "The aim of this study was to evaluate the relation between anthocyanins composition of acidified and non-acidified extracts from native and hybrid blue maize genotypes and their antiproliferative effect in mammary (MCF7), liver (HepG2), colon (Caco2 and HT29) and prostate (PC3) cancer cells. " 03/01/2015 - "This study suggests that the anthocyanins isolated from fruits of Vitis coignetiae Pulliat enhanced anti-cancer effects of CDDP by inhibiting Akt activity activated by CDDP." 05/01/2013 - "The objectives of this study were to characterize and measure the concentration of anthocyanins in pigmented potatoes and to evaluate their antioxidant and antimicrobial activities and their anti-proliferative effects in solid and hematological cancer cell lines. " 10/01/2011 - "Potential cancer chemopreventive activities of anthocyanins were revealed from in vitro studies. "
2.	Cardiovascular Diseases (Cardiovascular Disease) 04/01/2012 - "Epidemiological studies have indicated a positive association between the intake of foods rich in anthocyanins and the protection against cardiovascular diseases. " 06/01/2015 - "In vitro and in vivo studies suggest that dietary anthocyanins modulate cardiovascular disease risk; however, given anthocyanins extensive metabolism, it is likely that their degradation products and conjugated metabolites are responsible for this reported bioactivity. " 07/01/2011 - "To study the bioavailability of anthocyanins and the effects of a 20% blackcurrant juice drink on vascular reactivity, plasma antioxidant status and other cardiovascular disease risk markers. " 06/01/2015 - "These novel data provide evidence to suggest that anthocyanin metabolites are bioactive at physiologically relevant concentrations and have the potential to modulate cardiovascular disease progression by altering the expression of inflammatory mediators." 06/01/2013 - "The berries of blue honeysuckle (Lonicera caerulea L.), including an edible Kamchatka variety (var. kamtschatica Sevast.), are a potential but relatively unknown source of anthocyanins, which are thought to have favorable effects on diabetes and cardiovascular disease (CVD). "
3.	Inflammation 04/01/2015 - "The objective of this study was to evaluate the effect of anthocyanin (ANC)-enriched fractions from blackberry-blueberry beverages on inflammation and adipogenesis in an in vitro model of inflammation mimicking the pathologic interaction between adipocytes and macrophages. " 11/01/2009 - "In this study, we investigated whether anthocyanins from black soybean seed coats could stimulate wound healing while preventing excessive inflammation. " 06/01/2015 - "The aim of this review is to highlight the anti-inflammatory activity of anthocyanins, including their effect on the expression of several genes involved in inflammation. " 05/01/2015 - "Anthocyanins may have beneficial effects on lipid metabolism and inflammation and are demonstrated to have hepatoprotective properties in models of restraint-stress- and chemically-induced liver damage. " 04/01/2015 - "Anthocyanins from fermented berry beverages inhibit inflammation-related adiposity response in vitro."
4.	Colonic Neoplasms (Colon Cancer) 05/12/2010 - "These metabolites may explain the relationship between anthocyanin consumption and reduced incidence of colon cancer. " 12/01/2009 - "In conclusion, this study suggests that the anthocyanins isolated from Vitis coignetiae Pulliat induce apoptosis might at least in part through activating p38-MAPK and suppressing Akt in human colon cancer HCT-116 cells." 12/01/2009 - "In this study, we investigated the anthocyanins isolated from Vitis coignetiae Pulliat for their potential anti-proliferative and apoptotic effects on human colon cancer HCT-116 cells. " 10/22/2008 - "The objectives of this study were to compare the chemoprotective properties of anthocyanin-rich extracts (AREs) with variable anthocyanin profiles to understand the relationship between anthocyanin chemical structure and chemoprotective activity, measured as inhibition of colon cancer cell proliferation. " 12/01/2015 - "We previously showed that anthocyanin-containing baked purple-fleshed potato (PP) extracts (PA) suppressed early and advanced human colon cancer cell proliferation and induced apoptosis, but their effect on colon CSCs is not known. "
5.	Atherosclerosis 01/01/2013 - "This new insight may help to elucidate the molecular mechanisms underlying the vascular protection afforded by Dp, and anthocyanins in general, in the context of prevention of endothelial dysfunction and atherosclerosis. " 03/01/2014 - "The results of the present study demonstrate that anthocyanidins can directly bind with and suppress the activity of FAK with atherosclerosis-preventive effects." 09/01/2013 - "Atherosclerosis is a chronic inflammatory disease and previous studies have demonstrated that anthocyanin inhibits atherosclerosis. " 05/01/2012 - "To study the effect of Lycium ruthenicum anthocyanins on atherosclerosis (AS) in mice. " 06/22/2011 - "Our previous studies have demonstrated that anthocyanin extract from black rice (AEBR) inhibits atherosclerosis. "

Related Drugs and Biologics

1.	Anthocyanins (Anthocyanin)
2.	polyphenols
3.	cyanidin
4.	Flavonoids
5.	Insulin (Novolin)
6.	Glucose (Dextrose)
7.	Apolipoproteins E (ApoE)
8.	Isoflavones
9.	Tea
10.	Acids

Related Therapies and Procedures

1.	Oral Administration
2.	Chemoprevention
3.	Heterologous Transplantation (Xenotransplantation)
4.	Radiotherapy
5.	Bioreactors