HOME PRODUCTS SERVICES COMPANY CONTACT FAQ

Antazoline (Antazoline Phosphate)

An antagonist of histamine H1 receptors.

Also Known As:

Antazoline Phosphate; Analergine; Antasten; Antazoline Hydrochloride; Antazoline Phosphate (1:1); Antistine; Arithmin; Lannett Brand of Antazoline Phosphate; Hydrochloride, Antazoline; Phosphate, Antazoline; Imidamine; Phenazoline; 1H-Imidazole-2-methanamine, 4,5-dihydro-N-phenyl-N-(phenylmethyl)-

Networked: 73 relevant articles (4 outcomes, 6 trials/studies)

Relationship Network

Drug Context: Research Results

Heterocyclic Compounds: 60
- 1-Ring Heterocyclic Compounds
  - Azoles: 413
    - Imidazoles: 107
      - Antazoline: 73
        naphazoline mononitrate drug combination antazoline sulfate: 2
        pulsnorma: 2
        xylometazoline drug combination antazoline

Experts

1.	Czuczwar, Stanisław J: 3 articles (01/2008 - 08/2004)
2.	Wielosz, Marian: 2 articles (07/2005 - 08/2004)
3.	Lafon-Cazal, M: 2 articles (01/2003 - 09/2000)
4.	Milhaud, D: 2 articles (01/2003 - 09/2000)
5.	Bockaert, J: 2 articles (01/2003 - 09/2000)
6.	Grabowski, Marcin: 1 article (09/2015)
7.	Kołtowski, Łukasz: 1 article (09/2015)
8.	Piątkowska, Agnieszka: 1 article (09/2015)
9.	Balsam, Paweł: 1 article (09/2015)
10.	Lodziński, Piotr: 1 article (09/2015)

Related Diseases

1.	Atrial Fibrillation 01/01/2014 - "To assess safety and efficacy of antazoline for termination of atrial fibrillation (AF) occurring during ablation of accessory pathways (AP). " 09/01/2015 - "Antazoline for termination of atrial fibrillation during the procedure of pulmonary veins isolation." 01/01/2014 - "Antazoline for rapid termination of atrial fibrillation during ablation of accessory pathways." 01/01/2012 - "Clinical efficacy of antazoline in rapid cardioversion of paroxysmal atrial fibrillation--a protocol of a single center, randomized, double-blind, placebo-controlled study (the AnPAF Study)." 01/01/1976 - "[Antazoline and auricular fibrillation in the Wolff-Parkinson-White syndrome]."
2.	Pruritus (Itching) 08/01/1980 - "Antazoline inhibited itching (but not redness) to a significant degree in the same model. " 12/20/1954 - "[Treatment of gravidic hyperemesis, sialorrhea and vulvar pruritus with antistine]." 04/01/1990 - "The results of this study indicate that the combination of naphazoline and antazoline was more effective in inhibiting redness than naphazoline and more effective in inhibiting itching than antazoline. " 02/01/1981 - "The histamine H1 receptor antagonist, antazoline phosphate, blocked itching but not vasodilation in five humans pretreated with compound 48-80. " 08/01/1980 - "The combination of naphazoline and antazoline produced significant whitening and inhibition of itching in all eyes challenged by histamine. "
3.	Paroxysmal Tachycardia 01/01/1966 - "[Efficacy of antazoline in paroxysmal tachycardia]."
4.	Seizures (Seizure) 01/01/2003 - "In the high-dose group only, seizures completely ceased 1 h after the third injection of antazoline, then started again 1 h later. " 01/01/1999 - "Influence of antazoline on the anticonvulsant activity of conventional antiepileptic drugs against maximal electroshock-induced seizures in mice." 08/01/2004 - "The purpose of this study was to investigate the effects of antazoline and ketotifen (two H1 receptor antagonists) on the anticonvulsant activity of antiepileptic drugs against maximal electroshock (MES)-induced convulsions in mice. " 07/01/2005 - "The remaining histamine receptor antagonists studied i.e., antazoline (up to 1 mg/kg), cimetidine (up to 40 mg/kg) and famotidine (up to 10 mg/kg) had no impact on seizure susceptibility in aminophylline-induced convulsions. " 07/01/2005 - "The aim of this study was to evaluate the effects of H(1) (antazoline and astemizole) or H(2) (cimetidine and famotidine) histamine receptor antagonists on the clonic phase, tonic seizures and morality of mice challenged with aminophylline to induce convulsions in mice. "
5.	Allergic Conjunctivitis (Giant Papillary Conjunctivitis) 08/01/1975 - "A controlled, double-blind comparison of naphalzoline hydrochloride 0.05%, antazoline phosphate 0.5%, a combination of both components and a placebo was performed on 51 ragweed sensitive patients presenting allergic conjunctivitis. " 08/01/1975 - "Antazoline phosphate and naphazoline hydrochloride, singly and in combination for the treatment of allergic conjunctivitis-a controlled, double-blind clinical trial." 04/01/1990 - "Vasocon-A was found to significantly inhibit all five major signs and symptoms of allergic conjunctivitis: itching, redness, chemosis, lid swelling, and tearing, for more than 85% of the comparisons when compared over time with placebo, naphazoline alone, or antazoline alone. " 02/01/1997 - "[Antazoline/tetryzoline eyedrops in comparison with levocabastine eyedrops in acute allergic conjunctivitis]." 09/01/2010 - "In this multicenter, single-masked, randomized study, 240 patients with signs and symptoms of allergic conjunctivitis were randomized to receive 1 of the following 8 treatments twice daily: cromolyn sodium/chlorpheniramine maleate, diclofenac, epinastine, fluorometholone, ketotifen, levocabastine, naphazoline/antazoline, and olopatadine. "

Related Drugs and Biologics

1.	Naphazoline (Clear, All)
2.	Ketotifen (Ketotifene)
3.	Anticonvulsants (Antiepileptic Drugs)
4.	Astemizole
5.	Cromolyn Sodium (Cromoglicic Acid)
6.	Cimetidine (Biomet)
7.	levocabastine (Bilina)
8.	Famotidine (Pepcid)
9.	Histamine Receptors (Histamine Receptor)
10.	Fluorometholone (FML)

Related Therapies and Procedures

1.	Electric Countershock (Cardioversion)
2.	Intralesional Injections
3.	Anesthesia