Anomia (Dysnomia)

A language dysfunction characterized by the inability to name people and objects that are correctly perceived. The individual is able to describe the object in question, but cannot provide the name. This condition is associated with lesions of the dominant hemisphere involving the language areas, in particular the TEMPORAL LOBE. (From Adams et al., Principles of Neurology, 6th ed, p484)

Also Known As:

Networked: 40 relevant articles (2 outcomes, 7 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Wernicke Aphasia (Receptive Aphasia)
2.	Aphasia (Dysphasia)
3.	Stroke (Strokes)
4.	Memory Disorders (Memory Loss)
5.	Apraxias (Dyspraxia)

Experts

1.	Fridriksson, Julius: 2 articles (09/2011 - 06/2010)
2.	Laganaro, Marina: 2 articles (01/2011 - 12/2006)
3.	Schnider, Armin: 2 articles (01/2011 - 12/2006)
4.	Copland, David A: 1 article (05/2014)
5.	Read, Stephen: 1 article (05/2014)
6.	de Zubicaray, Greig: 1 article (05/2014)
7.	McMahon, Katie: 1 article (05/2014)
8.	van Hees, Sophia: 1 article (05/2014)
9.	Angwin, Anthony: 1 article (05/2014)
10.	Hoffmann, Michael: 1 article (11/2013)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Anomia:

1.	salicylhydroxamic acid (SHAM)IBA 09/01/2011 - "Both studies yielded positive findings in that anomia treatment outcome was improved when it was coupled with real brain stimulation as compared with a placebo (sham) condition. " 07/01/2011 - "In a randomized, double-blind, sham-controlled crossover trial, we assessed if anodal transcranial direct current stimulation compared to cathodal transcranial direct current stimulation and sham stimulation over the right temporo-parietal cortex would improve the success of short-term high-frequency anomia training. " 09/01/2013 - "In open and sham-controlled studies, a low-frequency, 1Hz stimulation of the non-lesioned hemisphere (the homologue of Broca's area) for a week or more significantly improved spontaneous speech and anomia in patients with non-fluent aphasia. " 06/01/2010 - "Ten patients with chronic stroke-induced aphasia received 5 days of anodal tDCS (1 mA for 20 minutes) and 5 days of sham tDCS (for 20 minutes, order randomized) while performing a computerized anomia treatment. "
2.	Neurotransmitter Agents (Neurotransmitter)IBA 09/01/2013 - "Both types of tDCS stimulation resulted in improved comprehension and reduced anomia, their primary modes of action are distinct, however, both share a common site of action with regard to the balance that occurs between inhibitory and excitatory neurotransmitters (synaptic and non-synaptic). "
3.	Levodopa (L Dopa)FDA LinkGeneric 01/01/2011 - "Crossover trial of subacute computerized aphasia therapy for anomia with the addition of either levodopa or placebo." 01/01/2011 - "To determine whether levodopa enhances the effect of intensive computer-assisted therapy (CAT) of anomia in the postacute stage of aphasia. "
4.	STF 62247IBA 09/01/2011 - "Here, I review four recent studies from my lab that focused on brain modulation associated with long-term anomia outcome, its behavioral treatment, and the use of transcranial brain stimulation to enhance anomia treatment success in individuals with chronic aphasia caused by left hemisphere stroke. "
5.	styrene-methylmethacrylate copolymerIBA 06/30/1961 - "Many larvae of the common bivalve, Anomia simplex, when grown under laboratory conditions, exhibited a partial metamorphosis. " 06/30/1961 - "Partial metamorphosis in Anomia simplex." 09/06/2013 - "Herein, we show how diffraction tomography can be used to determine the relative placement of the calcium carbonate polymorphs calcite and aragonite in the highly mineralized holdfast system of the bivalve Anomia simplex. "
6.	A-factor (Streptomyces)IBA 05/01/1997 - "The impact of anomia as a factor in a demand resource model of health." 10/01/1965 - "A factor analytic exploration of the alienation, anomia and authoritarianism domain."
7.	Dexfenfluramine (Redux)IBA 05/01/1993 - "Nominal dysphasia redux."
8.	Technetium Tc 99m Exametazime (Ceretec)FDA Link 02/01/2000 - "Using semiquantitative 99mTc-hexamethyl propyleneamine oxime (HMPAO) brain SPECT as a measure of regional cerebral blood flow (rCBF), we investigated the relationship between reduced 99mTc-HMPAO uptake and the severity of dysnomia in PPA. "
9.	Tuberculin (PPD)IBA 09/01/1981 - "Other unusual features of the index case include the restriction of the initial cognitive deficit to memory loss and mild anomia, the scarcity of antemortem evidence for systemic sarcoidosis, a positive tuberculin test, a cerebrospinal fluid (CSF) protein concentration as high as 2028 mg per deciliter. "
10.	TeaIBA 11/01/2003 - "Thus anomia for people's names may be the sole clinical manifestation of TEA. "

Therapies and Procedures

1.	Computer-Assisted Therapy (Therapy, Computer Assisted) 12/01/2006 - "In this study we analysed the outcome of computer-assisted therapy (CAT) for anomia on eight acute aphasic patients. " 11/01/2011 - "By the end of the paper you will be able to answer the CEU questions and consider whether to use computer assisted therapy on a wide range of clients with anomia difficulties." 11/01/2011 - "Fifteen participants with chronic aphasia (with a range from moderate to mild anomia) were recruited to 15 weeks of computer-assisted therapy for anomia. " 01/01/2011 - "To determine whether levodopa enhances the effect of intensive computer-assisted therapy (CAT) of anomia in the postacute stage of aphasia. "
2.	Aftercare (After-Treatment) 05/01/2014 - "This study investigated the integrity of the arcuate fasciculus (AF) and uncinate fasciculus (UF) before and after treatment for anomia in people with aphasia. " 09/01/2010 - "These findings are discussed with reference to the literature on the neural underpinnings of recovery after treatment for anomia in aphasia."
3.	Home Nursing (Nursing, Home) 07/01/2000 - "This study investigated the effects of two social environment variables, social support and anomia, on the self-reported health of older nursing home residents. "
4.	Anterior Temporal Lobectomy 07/01/1994 - "Dysnomia after left anterior temporal lobectomy without functional mapping: frequency and correlates." 07/01/1994 - "Within the context of group data suggesting minimal risk to language function when functional mapping is not used, a small subgroup of individuals characterized by a later onset of epilepsy can be identified who exhibit a surgically induced dysnomia after a standard left anterior temporal lobectomy. " 07/01/1994 - "A comparison of preoperative to (6 mo) postoperative performance on a standardized test of nominal speech revealed the following: 1) a statistically significant but clinically modest difference in outcome between left and right anterior temporal lobectomy groups; 2) a subgroup (7%) of left anterior temporal lobectomy patients exhibited a postoperative dysnomia (a decline in nominal speech that exceeded the worst performance in the right anterior temporal lobectomy group); and 3) a postoperative decline in nominal speech after left anterior temporal lobectomy was specifically associated with a later age at the onset of epilepsy. " 10/01/1990 - "Age at 1st risk for seizures may predict anomia following dominant anterior temporal lobectomy. "
5.	Highly Active Antiretroviral Therapy (HAART) 05/01/2006 - "Despite favorable immunological and virological response to highly active antiretroviral therapy, neurological symptoms and demyelinating lesions progressed during the first months, and right homonyous hemianopsia, acalculia, and color anomia were noted. "