Anions

03/01/2008 - "Elevation of anions in exercise-induced acidosis: a study by ion-exchange chromatography/mass spectrometry."
03/01/2015 - "Significantly fewer patients with unmeasured anions acidosis were identified with AGadj than with SIGcor (164 vs 230; P < .0001). "
02/01/2015 - "Metabolic acidosis correction is achieved by the transfer of bicarbonate and other buffer anions in dialysis. "
10/01/2013 - "Analysis of the gasometric parameters after 12 hours of treatment according to the Stewart approach compared to the Henderson-Hasselbalch concept disclosed that metabolic acidosis caused by the unidentified anions has resolved almost completely and been replaced by metabolic hyperchloremic acidosis. "
10/01/2013 - "Analysis of the blood gasometric parameters with the Stewart approach and the traditional Henderson-Hasselbalch concept enabled the discovery of metabolic acidosis caused by unidentified anions (mainly ketons). "

10/01/2003 - "The first inhibition study of the transmembrane, tumor-associated isozyme CA IX with anions is reported here. "
06/25/2015 - "The observation that in 4NI neutral radicals and radical anions are formed via DEA at high efficiency already at threshold (0 eV) may have significant implications for the development of nitroimidazole-based radiosensitizers in tumor radiation therapy."
12/17/2013 - "However, this work shows that these transporters based upon both natural products and purely synthetic supramolecular systems transport anions, depolarize acidic compartments within cancer cells and trigger apoptosis."
05/26/2009 - "Members of this family contribute to the excretion of several organic anions from cells and play a critical role in conferring resistance against drugs used in the treatment of cancer. "
04/01/2008 - "The retention of polyhedral borane anions within tumor cells has been attributed to the possible formation of covalent bonds with nucleophilic protein substituents. "

01/01/2008 - "Elimination of organic anions in response to an early stage of renal ischemia-reperfusion in the rat: role of basolateral plasma membrane transporters and cortical renal blood flow."
04/01/1992 - "The 0:100 Cl-:NO3- solution had no effect on compliance or contractility at physiological end-diastolic pressures but reduced the slope of the peak systolic pressure-volume relation by approximately 20% as end-diastolic pressure was increased above 10 mm Hg. In conclusion, anions appear to play a hitherto unrecognized role in arrhythmogenesis in ischemia and reperfusion. "
04/01/1992 - "The role of anions in the initiation of ischemia- and reperfusion-induced arrhythmias is unknown. "
08/01/1983 - "These data support the thesis that following low flow states bowel ischemia may be related to a reperfusion injury due to the release of toxic free radical anions."
01/01/2008 - "This study was undertaken to evaluate the cortical renal blood flow (cRBF) and the renal protein expression of the organic anion transporters (OAT1 and OAT3) in association with the elimination of organic anions in an early stage of renal ischemia-reperfusion. "

11/21/2008 - "Renal elimination of organic anions in cholestasis."
12/01/2004 - "Physiological cholestasis linked to immature hepatobiliary transport systems for organic anions occurs in rat and human neonates. "
05/01/2004 - "These results show that chronic Al exposure leads to oxidative stress, cholestasis, and impairment of the hepatic handling of organic anions by decreasing both sinusoidal uptake and canalicular excretion. "
01/25/2006 - "This study was conducted to determine if the ability of model organic anions to produce cholestasis is relevant to the protection against APAP hepatotoxicity afforded by ICG. "
10/13/2006 - "In cholestasis, the accumulation of organic anions in hepatocytes is reduced by transporters (multidrug resistance-associated proteins and OSTalpha-OSTbeta) able to extrude them across the basolateral membrane. "

08/01/2013 - "Therefore, the purpose of this study was to determine whether the strong ion gap-the gold standard for estimation of unmeasured anions-is elevated and associated with outcome in patients with hypoxic hepatitis. "
08/01/2013 - "The liver is a possible source of the unmeasured anions, which may represent markers of tissue damage in hypoxic hepatitis."
08/01/2013 - "Unmeasured anions are associated with short-term mortality in patients with hypoxic hepatitis."
08/01/2013 - "Unmeasured anions are elevated in patients with hypoxic hepatitis, contribute to metabolic acidosis and are associated with mortality. "