Angiokeratoma

12/01/1987 - "The argon laser, used in either a pulsed or continuous fashion, is highly effective for treatment of angiokeratomas. "
02/01/1995 - "Argon laser treatment of cutaneous multiple angiokeratomas."
02/01/1988 - "This article describes 2 patients with angiokeratoma circumscriptum for whom the argon laser proved to be a highly successful means of treatment. "
02/01/1988 - "Angiokeratoma circumscriptum: successful treatment with the argon laser."
12/01/1987 - "Argon laser treatment of angiokeratomas."

06/21/2023 - "Clinical and dermoscopic improvement of angiokeratoma in a child with topical rapamycin."
02/01/2021 - "Treatment of angiokeratomas of Fordyce with topical rapamycin 0.25% cream."
11/01/2020 - "This case presents a young female whose solitary angiokeratoma was treated with topical 1% sirolimus cream, improving the appearance, symptoms, and size of the lesion. "
11/01/2020 - "Topical sirolimus for treatment of a solitary angiokeratoma."
09/01/2020 - "Use of topical rapamycin in acral pseudolymphomatous angiokeratoma of children (APACHE): A report of two cases and review of the literature."

12/01/2022 - "Intralesional injection of triamcinolone acetonide is an effective treatment for angiokeratoma of the scrotum: a case report."

02/01/1984 - "In our patient with widespread angiokeratomas, the results of enzyme studies were normal, and there were no systemic problems or significant family history. "
01/01/1999 - "Cutaneous angiokeratomas are usually associated with enzyme defect disorders, such as Fabry's disease, and are linked in this work as a reactive pattern in hepatorenal failure. "
10/01/1996 - "However, it is well known that widespread angiokeratomas may also be found in other lysosomal enzyme disorders, as well as in patients with normal enzyme activities. "
01/01/2018 - "Affected males with classic FD have little or no enzyme activity and have an early onset of symptoms and signs, including acroparesthesias, hypohidrosis, angiokeratomas, gastrointestinal dysfunction and/or a characteristic corneal dystrophy during childhood/adolescence. "
02/01/1977 - "Patients with deficiency of this lysosomal enzyme, or fucosidosis, have spasticity, mental retardation, and retardation of growth in addition to angiokeratomas. "

12/01/2012 - "Acral pseudolymphomatous angiokeratoma of children: a case report with immunohistochemical study of antipodoplanin antigen."
01/01/2022 - "After treatment with several over-the-counter wart therapies, several rounds of paring plus cryotherapy, and Candida antigen injections failed, a shave biopsy was taken to remove the lesion, and histopathologic examination was consistent with an angiokeratoma. "

08/01/1991 - "These studies document the occurrence of two forms of alpha-N-acetylgalactosaminidase deficiency and sialopeptiduria, a severe infantile-onset form of neuroaxonal dystrophy without angiokeratoma or visceral lysosomal inclusions and an adult-onset form characterized by angiokeratoma, extensive lysosomal accumulation of sialoglycopeptides and the absence of detectable neurologic involvement."

02/01/1990 - "All of them were male and revealed to have angiokeratomas of the skin and markedly decreased activity of alpha-galactosidase--A in leukocytes. "
01/01/1985 - "The presence of these specific inclusions together with the decrease of leucocytic alpha-galactosidase allows the differential diagnosis with other types of angiokeratomas and some skin angiomas."
10/01/2011 - "This rash was diagnosed as angiokeratomas, and blood measurement of alpha-galactosidase A confirmed the suspicion of Fabry disease. "
04/01/2009 - "Three patients were diagnosed as Fabry's disease with clinical characteristics including pain and acroparesthesias, angiokeratoma and decrease of alpha-galactosidase A activity. "
03/18/2005 - "Fabry's disease had been diagnosed 2 years before, based on angiokeratoma and hypohidrosis on physical examination and complete lack of alpha-galactosidase A on laboratory examination. "

04/01/2012 - "In contrast, diffuse angiokeratomas should alert the physician to a possible diagnosis of Fabry disease, a rare X-linked lysosomal storage disorder, characterized by α-galactosidase deficiency. "
09/01/2019 - "The presence of skin angiokeratomas and cardiac hypertrophy prompted further positive investigation for Fabry disease (nondetectable α-galactosidase activity, excessively elevated lyso-Gb3, and pathogenic deletion in the GLA gene). "
01/07/2014 - "The patient showed signs such as cornea verticillata, angiokeratomas, cardiac and neurological manifestations, an end-stage renal disease and he had low α-galactosidase A activity. "
06/01/2002 - "The coexistence of painful acroparesthesias, angiokeratomas, left ventricular hypertrophy (LVH), corneal opacities and lenticular lesions suggested the diagnosis of Fabry's disease, which was confirmed by low serum levels of a-galactosidase-A activity. "
11/01/2008 - "Fabry disease is a lysosomal storage disorder that is caused by mutations in the gene encoding a-galactosidase A on Xq22.1. Typically hemizygous male patients exhibit classic phenotypes such as angiokeratoma, acroparesthesias, episodic pain "crises," hypohidrosis, and whorl-shaped corneal opacities from childhood. "

01/01/2009 - "Glycosphingolipid deposition in various tissues leads to episodic pain crises and acroparesthesias, gastrointestinal disturbances, angiokeratomas, corneal, and lenticular opacities, and eventually in the third to fifth decades of life, the kidney, heart and central nervous system are involved. "
01/01/2007 - "Fabry's disease is a congenital disorder of glycosphingolipid metabolism with an X-linked recessive inheritance, presenting with typical symptoms of pain crises, acroparesthesias, cutaneous and mucosal angiokeratomas, hypohidrosis, heart and kidney lesions, and other symptoms, which are described below. "
01/01/2002 - "Inability to prevent the progression of glycosphingolipid deposition causes significant morbidity (acroparesthesia, angiokeratoma, autonomic dysfunction, cardiomyopathy and deafness), and mortality from early onset strokes, heart attack and renal failure in adulthood. "
10/01/2008 - "Generalised systemic angiokeratoma constitute angiokeratoma corporis diffusum, a rare X-linked recessive inborn error of glycosphingolipid metabolism due to deficiency of alpha galactosidase A. "
01/01/2020 - "Fabry disease is an X-linked disorder of glycosphingolipid metabolism that results in progressive accumulation of neutral glycosphingolipids, predominantly globotriaosylsphingosine (Gb3) in lysosomes, as well as other cellular compartments of several tissues, causing multi-organ manifestations (acroparesthesias, hypohidrosis, angiokeratomas, signs and symptoms of cardiac, renal, cerebrovascular involvement). "

12/01/2021 - "ACN is one of the five disorders belonging to the group of angiokeratomas (AKs) that also include AK of Mibelli, AK of Fordyce, solitary or multiple AK, and AK corporis diffusum. "
12/01/2021 - "Based on clinical and histopathological features, a diagnosis of angiokeratoma circumscriptum naeviforme (ACN) was established. "
12/01/2014 - "Angiokeratoma circumscriptum naeviforme (ACN) is a congenital variant of angiokeratoma commonly present on the lower limb as a hyperkeratotic plaque. "
10/01/2014 - "We report here a case of congenital, linear, unilateral, verrucous plaques on the leg of a young girl, diagnosed as angiokeratoma circumscriptum neviforme (ACN). "
09/15/2011 - "Angiokeratoma circumscriptum naeviforme (ACN) is a still rarer type of angiokeratoma, which is typically seen at birth. "

11/01/2017 - "Several laser modalities are effective in treating multiple variants of angiokeratomas. "
11/01/2017 - "Lasers are a promising treatment option for angiokeratomas, but current use is limited by the lack of treatment guidelines. "
11/01/2017 - "To review the use and efficacy of lasers in treating angiokeratomas. "
11/01/2017 - "A PubMed search identified randomized clinical trials, cohort studies, case series, and case reports involving laser treatment of cutaneous angiokeratomas. "
03/01/2019 - "Multiple locally destructive modalities are available for the treatment of scrotal angiokeratomas; indeed, several lasers have effectively been used to treat angiokeratomas of the scrotum. "

01/01/2009 - "The long-pulse Nd:YAG laser is a highly effective and safe treatment for angiokeratoma of Fordyce."
04/01/2015 - "Long-pulsed Nd:YAG laser is an effective and safe therapeutic option for the treatment of solitary angiokeratomas. "
06/01/2009 - "We suggest that a long-pulsed Nd:YAG laser is a safe and effective method for the treatment of angiokeratoma of Fordyce."
01/01/2016 - "We conclude that angiokeratoma of Fordyce responded well to lpNd:YAG laser treatment. "
11/01/2020 - "Long-pulsed 1064-nm Nd:YAG laser in the treatment of multiple vulvar angiokeratomas."

09/01/2006 - "Pulsed dye laser is effective and safe for the treatment of angiokeratoma of Fordyce, with minimum side effects, providing an additional nonablative therapeutic option."
01/01/2022 - "This report reviews 2 cases of cutaneous angiokeratoma treated with surgical excision and a 595-nm pulsed dye laser (PDL) in which the patients showed improvement of symptoms and cosmetic appearance. "
01/01/2022 - "Cutaneous Angiokeratoma Treated With Surgical Excision and a 595-nm Pulsed Dye Laser."
12/01/2017 - "Genital angiokeratomas of Fordyce 595-nm variable-pulse pulsed dye laser treatment."
01/01/2015 - "Our experience confirmed the clinical efficacy and safety of the 595 nm pulse dye laser in the treatment of Mibelli angiokeratoma."

01/01/2015 - "Efficacy of 595nm pulsed dye laser therapy for Mibelli angiokeratoma."
01/01/2015 - "To retrospectively study the clinical efficacy of 595nm pulsed dye laser therapy for Mibelli angiokeratoma. "
03/01/2012 - "[Therapy for Angiokeratoma of Fordyce with the 940-nm Diode Laser]."
02/01/2010 - "Treatment of angiokeratoma of the vulva with pulsed dye laser therapy."
11/01/2020 - "Topical sirolimus cream may be a noninvasive treatment option for angiokeratomas with fewer risks than standard therapy that may be feasible and preferable for some patients."

01/01/2022 - "Fordyce Angiokeratoma: Comparison of Cryotherapy and Electrocauterization Treatments."
09/01/2021 - "Esthetically unpleasing or painful angiokeratomas can be locally excised or treated by laser- or cryotherapy. "
01/01/2016 - "Angiokeratoma of Fordyce can be easily diagnosed by their typical erythra and cured by varied therapeutic methods including surgery, electrocoagulation, cryotherapy, or various laser systems. "
11/01/2020 - "Angiokeratomas are benign vascular neoplasms that arise as solitary or multiple lesions, most commonly treated with excision, electrodessication, cryotherapy, or laser therapies. "
01/01/2022 - "After treatment with several over-the-counter wart therapies, several rounds of paring plus cryotherapy, and Candida antigen injections failed, a shave biopsy was taken to remove the lesion, and histopathologic examination was consistent with an angiokeratoma. "