Angiokeratoma

12/01/1987 - "The argon laser, used in either a pulsed or continuous fashion, is highly effective for treatment of angiokeratomas. "
02/01/1995 - "Argon laser treatment of cutaneous multiple angiokeratomas."
02/01/1988 - "This article describes 2 patients with angiokeratoma circumscriptum for whom the argon laser proved to be a highly successful means of treatment. "
02/01/1988 - "Angiokeratoma circumscriptum: successful treatment with the argon laser."
12/01/1987 - "Argon laser treatment of angiokeratomas."

01/01/1994 - "These findings confirm the heterogeneity of alpha-N-acetylgalactosaminidase deficiency and emphasize the need to consider this lysosomal storage disease in the differential diagnosis of patients with angiokeratoma."
08/01/1991 - "These studies document the occurrence of two forms of alpha-N-acetylgalactosaminidase deficiency and sialopeptiduria, a severe infantile-onset form of neuroaxonal dystrophy without angiokeratoma or visceral lysosomal inclusions and an adult-onset form characterized by angiokeratoma, extensive lysosomal accumulation of sialoglycopeptides and the absence of detectable neurologic involvement."

09/01/2008 - "Association of angiokeratoma of the vulva with angioma serpiginosum."
01/01/1979 - "Clinical and ultrastructural study of three cases of acquired nevoid telangioectasia: (1) angioma serpiginosum, (2) angiokeratoma neviformis, and (3) unilateral nevoid telangiectasia. "

08/01/1991 - "These studies document the occurrence of two forms of alpha-N-acetylgalactosaminidase deficiency and sialopeptiduria, a severe infantile-onset form of neuroaxonal dystrophy without angiokeratoma or visceral lysosomal inclusions and an adult-onset form characterized by angiokeratoma, extensive lysosomal accumulation of sialoglycopeptides and the absence of detectable neurologic involvement."

12/01/2012 - "Acral pseudolymphomatous angiokeratoma of children: a case report with immunohistochemical study of antipodoplanin antigen."

02/01/1990 - "All of them were male and revealed to have angiokeratomas of the skin and markedly decreased activity of alpha-galactosidase--A in leukocytes. "
01/01/1985 - "The presence of these specific inclusions together with the decrease of leucocytic alpha-galactosidase allows the differential diagnosis with other types of angiokeratomas and some skin angiomas."
10/01/2008 - "Generalised systemic angiokeratoma constitute angiokeratoma corporis diffusum, a rare X-linked recessive inborn error of glycosphingolipid metabolism due to deficiency of alpha galactosidase A. "
02/01/1998 - "In fact the "angiokeratoma circumscriptum" is a nevoid hamartomatous lesion arising early in life during infancy or childhood, sometimes in association with other congenital malformation of other sites, while the "angiokeratoma corporis diffusum" almost always occurs in association with enzyme disorders, usually alpha-galactosidase A enzyme deficiency (Anderson-Fabry disease), an X-linked recessive disorder affecting homozigous male patients in their adulthood. "
10/01/2011 - "This rash was diagnosed as angiokeratomas, and blood measurement of alpha-galactosidase A confirmed the suspicion of Fabry disease. "

04/01/2012 - "In contrast, diffuse angiokeratomas should alert the physician to a possible diagnosis of Fabry disease, a rare X-linked lysosomal storage disorder, characterized by α-galactosidase deficiency. "
01/01/2014 - "The patient showed signs such as cornea verticillata, angiokeratomas, cardiac and neurological manifestations, an end-stage renal disease and he had low α-galactosidase A activity. "
06/01/2002 - "The coexistence of painful acroparesthesias, angiokeratomas, left ventricular hypertrophy (LVH), corneal opacities and lenticular lesions suggested the diagnosis of Fabry's disease, which was confirmed by low serum levels of a-galactosidase-A activity. "
11/01/2008 - "Fabry disease is a lysosomal storage disorder that is caused by mutations in the gene encoding a-galactosidase A on Xq22.1. Typically hemizygous male patients exhibit classic phenotypes such as angiokeratoma, acroparesthesias, episodic pain "crises," hypohidrosis, and whorl-shaped corneal opacities from childhood. "
01/01/2010 - "Classically affected hemizygous males, with no residual α-galactosidase A activity may display all the characteristic neurological (pain), cutaneous (angiokeratoma), renal (proteinuria, kidney failure), cardiovascular (cardiomyopathy, arrhythmia), cochleo-vestibular and cerebrovascular (transient ischemic attacks, strokes) signs of the disease while heterozygous females have symptoms ranging from very mild to severe. "

11/01/2010 - "Biopsy showed acral skin with focal epidermal acanthosis that was centered on a dilated superficial vessel, consistent with an angiokeratoma. "
01/01/1996 - "The different entities causing vessel ectasia lead to the many clinical variants of angiokeratoma. "
04/30/2003 - "In classically affected hemizygotes clinical manifestations include pain in the extremities, vessel ectasia (angiokeratoma) in skin and mucous membranes, ophthalmological abnormalities, and hypohidrosis. "
12/01/2001 - "Clinical manifestations of Anderson-Fabry disease include excruciating pain in the extremities (acroparaesthesia), skin vessel ectasia (angiokeratoma), corneal and lenticular opacity, cardiovascular disease, stroke and renal failure, only renal failure being a frequent cause of death. "
01/01/1985 - "Some of the endothelium from haemangiomas and angiokeratomas was negative for factor VIII. The vessel walls of hemangiomas showed staining slightly positive for microfilaments (actin, myosin, filamin). "

12/01/2014 - "Angiokeratoma circumscriptum naeviforme (ACN) is a congenital variant of angiokeratoma commonly present on the lower limb as a hyperkeratotic plaque. "
10/01/2014 - "We report here a case of congenital, linear, unilateral, verrucous plaques on the leg of a young girl, diagnosed as angiokeratoma circumscriptum neviforme (ACN). "
01/01/2011 - "Angiokeratoma circumscriptum naeviforme (ACN) is a still rarer type of angiokeratoma, which is typically seen at birth. "
02/01/2005 - "Angiokeratoma circumscriptum naeviforme (ACN) is an unusual type of localized angiokeratoma that occurs more frequently in females and is usually located on the buttocks or thighs, showing a unilateral distribution. "

03/01/2011 - "Myoclonus and angiokeratomas in adult galactosialidosis."
12/01/1995 - "Fucosidosis and galactosialidosis are next well known diseases to produce angiokeratoma. "
08/01/2003 - "We saw a patient with galactosialidosis of the juvenile/adult form, a 51-year-old Japanese man with angiokeratomas on both elbows and knees, myoclonus, ataxia, mental retardation and macular cherry-red spots. "

06/01/2009 - "Various laser treatment modalities for angiokeratomas have been reported in the literature. "
02/01/2009 - "Angiokeratoma of the lower extremities: successful treatment with a dual-wavelength laser system (595 and 1064 nm)."
11/01/2001 - "Severe predominantly acral variant of angiokeratoma of Mibelli: response to long-pulse Nd:YAG (1064 nm) laser treatment."
04/01/2015 - "Long-pulsed Nd:YAG laser is more effective for the treatment of hyperkeratotic angiokeratomas due to deeper skin penetration of laser. "
07/01/2012 - "In this review, we will go through the dermoscopic and the confocal laser microscopy of diagnosis of most frequent vascular lesions (i.e., hemangiomas angiokeratoma, pyogenic granuloma, angiosarcoma) taking into particular consideration the differential diagnosis with amelanotic melanoma."

01/01/2009 - "The long-pulse Nd:YAG laser is a highly effective and safe treatment for angiokeratoma of Fordyce."
04/01/2015 - "Long-pulsed Nd:YAG laser is an effective and safe therapeutic option for the treatment of solitary angiokeratomas. "
06/01/2009 - "We suggest that a long-pulsed Nd:YAG laser is a safe and effective method for the treatment of angiokeratoma of Fordyce."
04/01/2015 - "A case of solitary angiokeratoma successfully treated with a 1064-nm long-pulsed Nd:YAG laser."
11/01/2014 - "We recommended the combined dual PDL-lpNd:YAG laser in treating severe hyperkeratotic and hyperplastic angiokeratoma of Mibelli. "

09/01/2006 - "Pulsed dye laser is effective and safe for the treatment of angiokeratoma of Fordyce, with minimum side effects, providing an additional nonablative therapeutic option."
01/01/2015 - "To retrospectively study the clinical efficacy of 595nm pulsed dye laser therapy for Mibelli angiokeratoma. "
01/01/2015 - "Efficacy of 595nm pulsed dye laser therapy for Mibelli angiokeratoma."
01/01/2015 - "Our experience confirmed the clinical efficacy and safety of the 595 nm pulse dye laser in the treatment of Mibelli angiokeratoma."
01/01/2015 - "50 cases of Mibelli angiokeratoma, from 10 to 41 year-old，were treated with the 595nm pulsed dye laser. "

02/01/1995 - "Angiokeratomas respond favorably to argon laser photocoagulation since vascular ectasias are localized in the papillary dermis. "
02/01/1995 - "Our report is designed to evaluate the efficacy of argon laser photocoagulation in the treatment of multiple angiokeratomas. "
12/01/1984 - "Argon laser photocoagulation of angiokeratomas of Fordyce, or scrotal angiomas, has been described. "

11/01/2013 - "Enzyme replacement therapy (ERT) for Fabry disease does not show a clear benefit in angiokeratoma. "
07/01/2005 - "Fabry disease: angiokeratoma, biomarker, and the effect of enzyme replacement therapy on kidney function."
01/01/2005 - "Angiokeratomas, Fabry disease and enzyme replacement therapy: still a challenge."
11/01/2013 - "Enzyme replacement therapy in two Japanese siblings with Fabry disease, and its effectiveness on angiokeratoma and neuropathic pain."