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Infected Aneurysm

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Aneurysm due to growth of microorganisms in the arterial wall, or infection arising within preexisting arteriosclerotic aneurysms.

Also Known As:

Aneurysm, Infected; Bacterial Aneurysm; Bacterial Aneurysms; Fungal Aneurysm; Aneurysm, Fungal; Aneurysms, Bacterial; Aneurysms, Fungal; Aneurysms, Infected; Aneurysms, Mycotic; Fungal Aneurysms; Infected Aneurysms; Mycotic Aneurysms; Aneurysm, Bacterial; Aneurysm, Mycotic; Mycotic Aneurysm

Networked: 430 relevant articles (15 outcomes, 9 trials/studies)

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Disease Context: Research Results

Related Diseases

1.	Infected Aneurysm
2.	Infection
3.	Aneurysm (Aneurysms)
4.	Endocarditis
5.	Rupture

Experts

1.	Choi, Donghoon: 3 articles (03/2014 - 10/2002)
2.	Gibbons, C P: 3 articles (08/2009 - 06/2000)
3.	Yamamoto, Hiroshi: 2 articles (11/2015 - 04/2009)
4.	Lee, Do Yun: 2 articles (03/2014 - 06/2006)
5.	Won, Jong Yun: 2 articles (03/2014 - 06/2006)
6.	Ko, Young-Guk: 2 articles (03/2014 - 10/2002)
7.	Delsing, Corine E: 2 articles (01/2013 - 04/2011)
8.	Laohapensang, Kamphol: 2 articles (01/2012 - 04/2010)
9.	Rutherford, Robert B: 2 articles (01/2012 - 04/2010)
10.	van Berge Henegouwen, D P: 2 articles (05/2011 - 10/2006)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Infected Aneurysm:

1.	Anti-Bacterial Agents (Antibiotics)IBA 01/01/1990 - "The five patients with infected aneurysms were treated successfully with antibiotics and surgical excision. " 10/01/2006 - "Prolonged courses of antibiotics are recommended for all patients with mycotic aneurysms. " 01/01/2000 - "Treatment is based on antibiotics and surgical management by removing of infected aneurysm and arterial restoration whenever possible. " 11/01/1995 - "Antibiotics were administered because a mycotic aneurysm was suspected. " 01/01/1990 - "We believe that patients not responding promptly to antibiotics or patients with infected aneurysms are best treated by surgical excision."
2.	Rifampin (Rifampicin)FDA LinkGeneric 02/01/2012 - "In situ replacement using rifampicin-bonded grafting and omental pedicle grafting is effective for treating mycotic aneurysms of the thoracic and abdominal aorta." 02/01/2012 - "Between December 2003 and December 2010, we performed surgical treatments in 23 patients (for the thoracic aorta in 6 patients, for the thoracoabdominal aorta in 8 patients, and for the abdominal aorta in 9 patients; 7 emergency, 10 urgent, and 6 elective operations) with mycotic aneurysm by using rifampicin-bonded grafting and omental pedicle grafting. " 02/01/2012 - "In situ replacement for mycotic aneurysms on the thoracic and abdominal aorta using rifampicin-bonded grafting and omental pedicle grafting." 02/01/2012 - "The objective of this report is to discuss the efficacy of in situ replacement for treating mycotic aneurysm, particularly using rifampicin-bonded grafts and omental pedicle grafts, on the basis of our 7 years of experience. " 05/01/2011 - "Treatment consisted of antibiotic therapy started preoperatively and continued postoperatively and an open repair, including resection of the infected aneurysm, replacement with a rifampin-soaked polyester graft, and an omental wrap covering the grafts. "
3.	PlatinumIBA 11/01/1996 - "The authors report on a 10-year-old boy who had a mycotic aneurysm of the common hepatic artery, which developed during the course of infective endocarditis of the mitral valve and was cured successively using a platinum coil embolization technique."
4.	glucuronyl glucosamine glycan sulfate (Vessel)IBA 07/01/1992 - "It also represents the first case in which a mycotic aneurysm of an infrapopliteal vessel was managed successfully with restoration of circulation." 07/01/1992 - "Peripheral mycotic aneurysms can occur when septic emboli lodge in either the lumen or the vasa vasorum of a peripheral vessel. " 05/01/2011 - "We report a unique case of a mycotic aneurysm of the left anterior descending coronary artery with a history of two-vessel off-pump coronary artery bypass graft surgery 9 months previously. " 02/01/2011 - "An infected aortic aneurysm, or mycotic aneurysm, is a rare arterial dilatation due to destruction of the infected vessel wall. " 12/01/2009 - "Mycotic aneurysms are rare, resulting from diffusion of infection to the vessel wall. "
5.	Fibrin Tissue Adhesive (Fibrin Sealant)IBA 12/01/1984 - "A suspension of fibrin glue and antibiotic for local treatment of mycotic aneurysms in endocarditis--an experimental study." 12/01/1984 - "We conclude that a suitable antibiotic suspended in fibrin glue may allow for the sterilization of mycotic aneurysms in bacterial endocarditis."
6.	Coarctation of the aortaIBA 05/01/2014 - "Mycotic aneurysm in a child with history of coarctation of the aorta repair." 01/01/2012 - "Streptococcus pneumoniae causing mycotic aneurysm in a pediatric patient with coarctation of the aorta." 04/01/1973 - "Ruptured mycotic aneurysm complicating coarctation of the aorta." 04/01/1973 - "Surgical treatment of mycotic aneurysm associated with coarctation of the aorta." 04/01/1964 - "PRESTENOTIC MYCOTIC ANEURYSM COMPLICATING COARCTATION OF THE AORTA.REPORT OF A CASE."
7.	Polyethylene Terephthalates (Polyethylene Terephthalate)IBA 08/01/1982 - "Dacron patch closure of aortic annulus mycotic aneurysms." 01/01/1998 - "A 68-year-old man with an infrarenal mycotic aneurysm underwent successful in-situ graft reconstruction using a woven Dacron graft. " 08/01/2010 - "Open debridement in an in situ reconstruction with Dacron grafts followed by antibiotic therapy seems to be a suitable therapeutic regime for mycotic aneurysms due to L. " 01/01/2003 - "We report the case of a 3-year-old girl in whom an infected aneurysm of the ascending aorta was successfully repaired by Dacron patch angioplasty under cardiopulmonary bypass." 05/01/2003 - "Five had mycotic aneurysms (3 aortic, 1 iliac and 1 femoral), 21 had prosthetic graft infections (9 aortic, 8 femoro-femoral, 2 axillo-femoral, 1 ilio-femoral and 1 femoral dacron patch) and one underwent superior mesenteric artery reconstruction following ischaemic small bowel perforation.Arterial"
8.	Polytetrafluoroethylene (Teflon)FDA Link 06/01/1992 - "We made a patch closure of the mycotic aneurysm, and aortic valve replacement using the Teflon felt reinforcing method. " 07/01/2010 - "In situ polytetrafluoroethylene graft bypass for primary infected aneurysm of the infrarenal abdominal aorta." 03/01/1992 - "The use of polytetrafluoroethylene graft for aortic reconstruction after suprarenal mycotic aneurysm resection has not been previously reported. " 10/01/1990 - "In additional 2 patients with infected aneurysm of right coronary sinus of Valsalva rupturing into the right ventricle, the aneurysm and infected tissue in the right ventricular outflow tract were completely resected and the defect of aortic sinus and VSD were closed with double Teflon fabric patches. " 01/01/1984 - "Two patients with polytetrafluoroethylene (PTFE) grafts developed mycotic aneurysms at the suture lines. "
9.	tranilast (N 5')IBA 01/01/2013 - "MRI findings included ischaemic lesions (n = 25), haemorrhagic lesions (n = 2), subarachnoid haemorrhage (n = 5), brain abscess (n = 6), mycotic aneurysm (n = 7), vascular occlusion (n = 3) and cerebral microbleeds (n = 17). " 11/01/2005 - "At presentation, primary organs involved included the lungs (58%; n = 33), genitourinary system (11%; n = 6), skin and soft tissue (9%; n = 5), bone and joints (4%; n = 2), central nervous system (4%; n = 2), mycotic aneurysm (2%; n = 1) and peritonitis (2%; n = 1). " 01/01/2004 - "The following lesions were surgically managed: mycotic aneurysms (N = 5), atherosclerotic aneurysms (N = 13) or obstructions (N = 11) of the aorta and iliac arteries, and stenoses of the artery supplying the grafted kidney (N = 125). " 05/01/1991 - "Eleven selected patients underwent in situ aortic graft reconstruction in the setting of mycotic aneurysm (n = 5), secondarily infected aortic aneurysm (n = 1), primary aortoenteric fistula (n = 1), and secondary aortoenteric fistula (n = 4). " 05/01/2009 - "Primary indications included degenerative aneurysms (n = 121), type B aortic dissection (n = 44), mycotic aneurysms (n = 9), traumatic disruptions (n = 9), intramural hematoma (n = 5), pseudoaneurysm (n = 4), and miscellaneous pathology (n = 5). "
10.	Vancomycin FDA LinkGeneric 09/15/2008 - "Fatal bacteremic mycotic aneurysm complicated by acute renal failure caused by daptomycin-nonsusceptible, vancomycin-intermediate, and methicillin-resistant Staphylococcus aureus." 01/01/1991 - "Of greater concern, four of four patients with left-sided endocarditis or mycotic aneurysm failed to recover when given teicoplanin, as opposed to one of three patients given vancomycin (P = 0.07). " 05/01/2000 - "When Staphylococcus aureus is repeatedly positive in blood cultures even under effective antibiotics therapy (vancomycin, teicoplanin, or rifampin), computed tomography scan and sonography should be performed early to exclude mycotic aneurysm of the deeply seated arteries, especially in patients with abdominal aortic calcification. "

Therapies and Procedures

1.	Transplants (Transplant) 01/01/2012 - "An in situ graft interposition and omental wrapping is a safe option for revascularization of infected aneurysms of the iliac arteries and infrarenal aorta." 03/01/1999 - "In the cardiovascular system, labeled leukocyte scintigraphy is very useful for diagnosing mycotic aneurysms and infected prosthetic vascular grafts, with a sensitivity of about 90%. " 05/01/2011 - "The aim of this study was to evaluate patients, who underwent spiral vein reconstruction of the abdominal aorta to repair infected aneurysms or replace infected aortic grafts. " 12/01/1999 - "The study aim was to report six cases of mycotic aneurysms in renal transplant patients and to review the literature on this subject. " 01/01/2016 - "Emergency computed tomography scan showed a large mycotic aneurysm arising from the right common carotid artery, and he underwent emergency open exploration with interposition bypass graft. "
2.	Homologous Transplantation (Allograft) 06/01/2015 - "Aortic Arch Mycotic Aneurysm Due to Scedosporium Apiospermum Reconstructed With Homografts." 08/01/2012 - "There also were only a few reports of "true" mycotic aneurysms of the renal allograft artery. " 08/01/2012 - ""True" mycotic aneurysm of the anastomotic site of the renal allograft artery." 08/01/2011 - "Endovascular repair of a pancreatic allograft mycotic aneurysm: two-year follow-up." 05/01/2006 - "To the best of our knowledge, this represents the first carefully documented, unique case of a Nocardia-infected aneurysm treated with homograft interposition. "
3.	Stents 09/01/2013 - "The use of covered stents in intracranial vasculature can be an effective and safe treatment modality for exclusion of the mycotic aneurysm in selected cases. " 10/01/2012 - "The study excluded patients with urgent or emergency indications, thoracoabdominal or mycotic aneurysm, and those requiring chimney stents, fenestrations, or visceral debranching procedures. " 01/01/2016 - "In this report, we present the case of a patient with mycotic aneurysms, disseminated peripheral and cerebral septic embolizations, and infected vegetations associated with a stent that had previously been deployed to treat restenosis of surgically corrected SVAS in the infancy. " 05/01/2015 - "Despite excellent immediate angiographic results and hemodynamic stabilization, repeat angiogram two weeks later showed mycotic aneurysms at the site of stent placement. " 05/01/2012 - "Coronary artery mycotic aneurysm is the diagnostic challenge of the stent era."
4.	Blood Vessel Prosthesis 08/01/2005 - "Thus, an infected aneurysm was effectively treated with a RFP-soaked vascular prosthesis and omentopexy." 12/01/1998 - "The use of cryopreserved arterial allografts is a more effective treatment for mycotic aneurysms and infected vascular prostheses than conventional surgical techniques." 12/01/1998 - "Seventy-two patients with mycotic aneurysms (n = 29) or infected vascular prostheses (n = 43) of the thoracic (n = 26) or abdominal aorta (n = 46) were treated with in situ repair and extra-anatomic reconstruction using prosthetic material (n = 38) or implantation of a cryopreserved arterial allograft (n = 34). " 04/01/2011 - "Endocarditis, mycotic aneurysm, and vascular prosthesis infection are common manifestations. " 08/01/2006 - "Systemic connective tissue disease was confirmed in 17 patients, lymphoma in three patients, inflammatory bowel disease in two patients, vascular prosthesis infection in seven patients, infection of a hip or knee replacement in seven patients, mycotic aneurysm in two patients, abscess in four patients and AIDS in one patient. "
5.	Angioplasty (Angioplasty, Transluminal) 06/01/2005 - "She was evaluated for replacement of the aortic valve and underwent a repeat angiogram, which demonstrated a mycotic aneurysm at the site of the angioplasty. " 06/01/2003 - "We report a case of a mycotic aneurysm of the extracranial carotid artery in an immunosuppressed patient successfully treated by wide excision and saphenous vein patch angioplasty." 02/01/2003 - "Endoluminal repair is an alternative to open surgery for the treatment of infected aneurysms of the thoracic aorta." 05/01/1999 - "Mycotic aneurysm after percutaneous transluminal femoral artery angioplasty." 03/01/1992 - "Postoperative mycotic aneurysm of the thoracic aorta at the site of subclavian flap angioplasty (SFA) is very rare. "