Neonatal Anemia

01/01/2023 - "For the simplicity and consistency of detection, we advocate defining neonatal anemia as a hemoglobin level or hematocrit below the 5th percentile of the reference population, which is highly dependent on gestational and postnatal ages. "
09/01/2022 - "Neonatal anemia was defined as hemoglobin <15 g/dL. "
01/01/2022 - "The primary outcome was neonatal anemia, defined as hemoglobin levels less than the fifth percentile for gestational age. "
05/11/2020 - "We compared the performance of KBT and MCA-PSV to predict neonatal anemia (Hemoglobin at birth under 13.5 g/dL) and severe neonatal anemia (Hb < 10 g/dL). "
01/01/2018 - "Secondary outcomes were neonatal intensive care unit admission and neonatal anemia (hemoglobin value less than 13.5 g/dL). "

02/01/2009 - "The establishment of effective treatment of neonatal anemia using recombinant human erythropoietin (r-HuEPO) requires a thorough understanding of the physiology and mechanism of EPO's pharmacologic effect. "
09/01/2020 - "The role of recombinant Human erythropoietin in neonatal anemia."
02/01/2009 - "Erythropoietin pharmacokinetic/pharmacodynamic analysis suggests higher doses in treating neonatal anemia."
12/01/2000 - "[Neonatal anemia and Rhesus incompatibility: is there a place for erythropoietin?]."
12/01/1999 - "[Prevention of neonatal anemia with recombinant human erythropoietin: a cost-benefit analysis]."

01/01/2004 - "Despite the high prevalence of neonatal anemia in Côte d'Ivoire, complete blood counts and iron studies have not been adequately explored. "
01/01/2021 - "Conclusion: A daily dose of 2 mg/kg iron supplement is beneficial to maintain iron homeostasis in majority preterm infants within 6 months regardless of their neonatal anemia history. "
03/15/2001 - "Flexed-tail animals have axial skeletal abnormalities and a transient embryonic and neonatal anemia characterized by pathologic intramitochondrial iron deposits in erythrocytes. "
02/01/1987 - "Treatment of newborn pigs with supplemental iron is a common procedure utilized to prevent neonatal anemia. "
01/01/2021 - "The objective of this study was to characterize cord ERFE concentrations at birth and assess interrelations between ERFE, iron regulatory hormones, and iron status biomarkers in 2 cohorts of newborns at higher risk of neonatal anemia. "

01/01/2021 - "The objective of this study was to characterize cord ERFE concentrations at birth and assess interrelations between ERFE, iron regulatory hormones, and iron status biomarkers in 2 cohorts of newborns at higher risk of neonatal anemia. "

01/01/2021 - "The objective of this study was to characterize cord ERFE concentrations at birth and assess interrelations between ERFE, iron regulatory hormones, and iron status biomarkers in 2 cohorts of newborns at higher risk of neonatal anemia. "

06/01/2014 - "The transfusion of red blood cells from umbilical cord blood (cord RBCs) is gathering significant interest for the treatment of fetal and neonatal anemia, due to its high content of fetal hemoglobin as well as numerous other potential benefits to fetuses and neonates. "
02/01/1991 - "Fetal hemoglobin in neonatal anemia."
11/01/2021 - "In this retrospective study within the Kaiser Permanente Northern California medical system, cases of fetomaternal hemorrhage were defined by either an elevated fetal hemoglobin level as determined by flow cytometry for a concerning pregnancy outcome (preterm delivery, perinatal demise, neonatal anemia, or transfusion within the first 2 days of life) or by perinatal demise with autopsy findings suggestive of fetomaternal hemorrhage. "
01/01/1963 - "Relation of maternal fetal hemoglobin and bilirubin to neonatal anemia, type of delivery, and outcome of pregnancy."

08/24/2010 - "Here we show that the semidominant mouse mutation Nan ("neonatal anemia") carries a single amino acid change (E339D) within the second zinc finger of the erythroid Krüppel-like factor (EKLF), a critical erythroid regulatory transcription factor. "
01/01/2017 - "We show that the semi-dominant neonatal anemia (Nan) mutation in the EKLF/KLF1 transcription factor leads to ectopic expression of proteins that are not normally expressed in the red blood cell, leading to systemic effects that exacerbate the intrinsic anemia in the adult and alter correct development in the early embryo. "

11/01/2000 - "The human Kell blood group system is important in transfusion medicine, since Kell is a polymorphic protein and some of its antigens can cause severe reactions if mismatched blood is transfused, while maternal alloimmunization may lead to fetal and neonatal anemia. "
01/01/2017 - "We show that the semi-dominant neonatal anemia (Nan) mutation in the EKLF/KLF1 transcription factor leads to ectopic expression of proteins that are not normally expressed in the red blood cell, leading to systemic effects that exacerbate the intrinsic anemia in the adult and alter correct development in the early embryo. "

01/01/2021 - "Neonatal anemia may compromise oxygen transport to the brain. "
12/01/1981 - "Experiments to determine the effect of the oxygen-hemoglobin dissociation curve on oxygen delivery during neonatal anemia, were carried out on 15 sedated and ventilated lambs less than 48 hr of age. "

12/01/2013 - "Although comparable RCS results can be achieved using Kidd antigen mismatches, BioRBCs are preferred for investigating neonatal anemia because biotin labeling of both allogeneic and autologous RBCs is possible."
11/01/2000 - "The human Kell blood group system is important in transfusion medicine, since Kell is a polymorphic protein and some of its antigens can cause severe reactions if mismatched blood is transfused, while maternal alloimmunization may lead to fetal and neonatal anemia. "

01/01/2019 - "It has been established that delayed umbilical cord clamping in preterm infants results in improvement in neonatal anemia, need for transfusion, incidence of necrotizing enterocolitis, and intraventricular hemorrhage by increasing neonatal circulating blood volume. "
08/01/2022 - "• Delayed cord clamping had significant benefits for newborns by increasing neonatal hemoglobin levels and reducing the risk of neonatal anemia, etc. • Delayed cord clamping may lead to neonatal hyperemia, erythrocytosis, and hyperbilirubinemia, which increases the risk of neonatal jaundice. "

02/01/2009 - "In extrapolating from the animal pilot experiment, the present study provides a case for the use of higher r-HuEPO doses in human studies to determine if higher doses are more effective in treatment of neonatal anemia to reduce, and in some less severe cases, eliminate, the need for blood transfusions."
07/01/2015 - "Two cases complicated by neonatal anemia required a postnatal blood transfusion. "
01/01/2012 - "The methodology excluded patients with a high likelihood of receiving blood transfusions and those who had a diagnosis of neonatal anemia. "
10/01/1984 - "Erythrocyte concentrates are preferred increasingly to whole-blood transfusions in treatment of neonatal anemias. "
01/01/2020 - "The most commonly reported fetal/neonatal outcomes included fetal heart rate, gestational age at delivery, birthweight, Apgar score, presence of neonatal anemia, cord blood gas measurements, need for blood transfusion, and death. "

03/01/2012 - "Risk factors in our study included emergent Caesarian Section, preterm labor (<37w), low birth weight (<2500g), 5 minute Apgar (less than 6), need for resuscitation, nuchal cord, impaired Biophysical Profile, neonatal anemia, and maternal infertility. "

01/01/1995 - "Although optimal RBC transfusion therapy has been a long-term challenge for neonatologists, the emergence of recombinant EPO as promising therapy for neonatal anemia is the major issue for 1994. "
08/01/2012 - "Although preventing anemia in this population, along with efforts to establish optimal red blood cell (RBC) transfusion and pharmacologic therapy continue to be actively investigated, the present review focuses exclusively on nonpharmacological approaches to the prevention and treatment of neonatal anemia. "
10/01/2019 - "Routine erythropoietin (Epo) therapy for neonatal anemia is presently controversial due to its modest response. "
01/28/1999 - "Erythropoietin therapy, often at doses much higher than those used in the adult, should be seriously considered in most cases of non-hypoplastic neonatal anemias, to minimise maximally the use of transfusions."
01/28/1999 - "We describe the four most common groups of neonatal anemia and their treatments, with particular emphasis on erythropoietin therapy. "

01/01/2022 - "We report on an Italian newborn presenting with severe neonatal anemia that required red blood cell transfusion. "
12/01/2004 - "A term infant girl received a red blood cell transfusion at birth for neonatal anemia (hemoglobin 75 g/L) initially attributed to abruptio placentae. "