Macrocytic Anemia

12/01/2001 - "Her macrocytic anemia dramatically improved after intramuscular administration of vitamin B12. "
07/01/1993 - "Moreover, vitamin B12 does not reverse the associated macrocytic anemia nor are the neurological deficits of MS improved following supplementation with vitamin B12. "
01/01/2012 - "He also showed severe macrocytic anemia with low vitamin B12, and an infiltrative shadow was found in the right lung on an X-ray. "
08/01/2009 - "A total of 81 ABG patients had cobalamin deficiency and macrocytic anemia (Group 1-PA), 36 had cobalamin deficiency without macrocytic anemia (Group 2), and 48 had normal cobalamin levels (Group 3). "
04/01/2007 - "He had macrocytic anemia with normal serum level of vitamin B12 (B12). "

02/01/1992 - "The macrocytic anemia resolved and hepatic synthetic function improved after discontinuation of valproate therapy. "
02/01/1992 - "Three years after starting valproate, he developed erythrocyte aplasia with a severe, normochromic, macrocytic anemia requiring several blood transfusions. "
12/01/2007 - "Valproic acid therapy is widely prescribed for seizure disorders and is often associated with thrombocytopenia, macrocytic anemia and a reversible dysmyelopoiesis. "
03/01/1997 - "Dose-related thrombocytopenia and macrocytic anemia associated with valproate use in bipolar disorder."

08/01/1993 - "Leucovorin was only partially protective against TMX-induced macrocytic anemia and the degree of protection was not dose-related. "
05/15/1990 - "[Folinic acid in the treatment of elderly patients with macrocytic anemia]."
01/01/1954 - "[Therapeutic effect of folinic acid in macrocytic anemias]."

06/01/1993 - "After 1 year, macrocytic anemia developed and the thiamine therapy was started at 75 mg/day. "
09/01/2009 - "Laboratory examination indicated the presence of pancytopenia with macrocytic anemia; further, decreased vitamin B1 and B12 levels were detected in her serum. "
06/01/1993 - "During the follow-up, the insulin requirement decreased and even ceased, and macrocytic anemia improved with thiamine treatment. "
06/01/1993 - "After thiamine therapy was ceased an increase in insulin requirement was observed and macrocytic anemia developed again."

08/01/2013 - "We now report two sisters, the eldest of which presented to a different hospital during childhood with sensorineural deafness, which was treated with a hearing prosthesis, insulin requiring diabetes, retinitis pigmentosa, optic atrophy, and macrocytic anemia. "
06/01/1993 - "During the follow-up, the insulin requirement decreased and even ceased, and macrocytic anemia improved with thiamine treatment. "
06/01/1993 - "After thiamine therapy was ceased an increase in insulin requirement was observed and macrocytic anemia developed again."

12/01/1990 - "The case is discussed in the context of a diagnostic differentiation between transient erythroblastopenia of childhood (TEC) and Diamond-Blackfan Anemia (DBA); since it does not clearly fit either category it could either be an unusual TEC presentation with extended macrocytic anemia dependent on steroid therapy for remission, or a late onset DBA with potential for eventual relapse."

01/01/1947 - "Metabolic function of pteroylglutamic acid and its hexaglutamyl conjugate; hematologic and urinary excretion studies on patients with macrocytic anemia."
12/01/1945 - "Further studies on folic acid in the treatment of macrocytic anemia."
06/01/2008 - "Only 7% of the patients tested had a macrocytic anemia; these patients were more likely than those without macrocytic anemia to have low folic acid levels (2.8% vs 0.4%, p < .03). "
11/01/2007 - "Macrocytic anemia with concurrent B12 or folate deficiency was rare (3%). "
09/01/2000 - "Folate and B12 deficiencies may result in macrocytic anemia, and are common in major depression; hypofolatemia may result in poorer antidepressant response. "

01/01/2011 - "No major abnormalities of iron metabolism are seen in patients with chronic alcohol ingestion besides the well-known macrocytic anemia. "
11/01/1985 - "Iron deficiency and macrocytic anemia were sometimes observed in 5 and 4 patients respectively. "
08/01/1957 - "Serum iron changes in nutritional macrocytic anemia during erythrocytic response with antimegaloblastic drugs; early drop in serum iron as an index of erythropoietic response."
05/01/1987 - "To evaluate the performance of serum iron studies as a diagnostic test for iron-deficiency anemia in a county hospital, the authors identified retrospectively all general medicine patients who had had bone-marrow aspirates for the work-up of non-macrocytic anemias from 1978 through 1983. "
02/01/1993 - "After ten months' TPN, macrocytic anemia and neutropenia developed and iron preparation was administered without hematological improvement. "

01/01/1951 - "[Therapeutic results of folic acid and liver extracts in eleven cases of nutritional macrocytic anemia]."
01/01/1953 - "[Anti-pernicious anemia principle, crude liver extracts and thymine; studies on their activity in experimental macrocytic anemia in rats]."
12/01/1962 - "[Results of treatment with folic acid, liver extracts and vitamin B12 on the clinical and hematological characteristics of 25 cases of nutritional macrocytic anemia]."

03/01/1946 - "The substitution of thymine for folic acid in the treatment of macrocytic anemias in relapse."
01/01/1953 - "[Anti-pernicious anemia principle, crude liver extracts and thymine; studies on their activity in experimental macrocytic anemia in rats]."

05/01/1992 - "A 77 year-old man, who had received total gastrectomy and splenectomy 11 years ago for gastric cancer was transferred to our hospital because of severe macrocytic anemia. "
08/01/1990 - "One hundred and thirty-seven cases of stomach cancer given fluoropyrimidines (UFT: 66 cases, Tegafur: 58 cases, 5-FU: 13 cases) after gastrectomy as the adjuvant chemotherapy were examined as to appearance of macrocytic anemia. "
07/29/1954 - "Absorption of radioactive vitamin B12 after total gastrectomy; relation to macrocytic anemia and to the site of origin of Castle's intrinsic factor."
05/01/1946 - "Observations on the utilization of folic acid (vitamin BC) and vitamin BC conjugate by persons with pernicious anemia and macrocytic anemia following gastrectomy."

01/01/1950 - "[Hemolytic macrocytic anemia due to splenic tuberculosis; diagnosis by puncture biopsy of the liver; splenectomy; cure]."
05/01/1992 - "A 77 year-old man, who had received total gastrectomy and splenectomy 11 years ago for gastric cancer was transferred to our hospital because of severe macrocytic anemia. "
06/01/1950 - "Experimental anemias in the rat; I. Macrocytic anemia in chronic pteroylglutamic acid deficiency and after splenectomy in Bartonella muris infection."

09/01/2004 - "Our patient presented with disfiguring depression of the left upper arm following vitamin B12 injections for macrocytic anemia secondary to Crohn's disease. "
03/01/1957 - "Reciprocal elevation in serum levels produced by injections of vitamin B12 and folic acid in patients with nutritional macrocytic anemia."

04/01/2011 - "Unexplained macrocytic anemia was common in our hemodialysis (HD) unit. "
01/14/1984 - "The incidence of macrocytic anemia has been investigated in 32 patients on maintenance hemodialysis (mean age 46 years, mean duration of dialysis treatment 27.5 months), in 18 patients with combined hemodialysis (HD) and hemofiltration (HF) treatment (mean age 42 years, mean duration of combined HD and HF treatment 6.3 months) and in 32 patients after renal transplantation (mean age 41 years, mean observation period since successful renal transplantation 55.2 months). "

09/01/2002 - "Our results showed that oral administration of AZA (10 mg/kg/day) to rabbits for two weeks induced reversible thrombocytosis and delayed fatal macrocytic anemia. "
11/01/1951 - "Oral administration of vitamin B12 concentrate in tropical sprue and nutritional macrocytic anemia."