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Androsterone

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A metabolite of TESTOSTERONE or ANDROSTENEDIONE with a 3-alpha-hydroxyl group and without the double bond. The 3-beta hydroxyl isomer is epiandrosterone.

Also Known As:

3-alpha-Hydroxy-5-alpha-Androstan-17-One; 5 alpha-Androstan-3 alpha-ol-17-one; Epiandrosterone; 3 alpha Hydroxy 5 alpha Androstan 17 One; 5 alpha Androstan 3 alpha ol 17 one; Androstan-17-one, 3-hydroxy-, (3alpha,5alpha)-

Networked: 133 relevant articles (5 outcomes, 9 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Hill, Martin: 2 articles (06/2014 - 10/2010)
2.	Kim, Won-Joo: 2 articles (06/2014 - 06/2005)
3.	Wolin, Michael S: 2 articles (08/2013 - 06/2006)
4.	Morfin, Robert: 2 articles (06/2012 - 04/2012)
5.	Mróz, Katarzyna: 2 articles (01/2010 - 05/2009)
6.	Tutka, Piotr: 2 articles (01/2010 - 05/2009)
7.	Mróz, Tomasz: 2 articles (01/2010 - 05/2009)
8.	Papageorgiou, A: 2 articles (04/2005 - 07/2004)
9.	Dalezis, P: 2 articles (04/2005 - 07/2004)
10.	Athanassiou, A E: 2 articles (04/2005 - 07/2004)

Related Diseases

1.	Psoriasis (Pustulosis Palmaris et Plantaris) 01/01/1994 - "Quantitative and qualitative analysis of chromatograms in 40 patients and 30 controls permitted assessment of excretion of 17-ketosteroids, hydroxyandrosterone, etiocholanolone, androsterone, dihydroepiandrosterone, beta-cortol compounds, etc., which is important in studies of psoriasis pathogenesis and in assessment of the efficacy of treatment of this and other diseases."
2.	Fatigue 11/01/1996 - "This study is a counterpart of the pilot study on the clinical management of chronic fatigue syndrome (CFS) by the combined use of the old (annex-free) and the new (dehydro-epiandrosterone- annexed) vitamin C infusion treatments with and without oral intake of erythromycin and chloramphenicol. "
3.	Neoplasms (Cancer) 06/01/1960 - "[Characteristics of tissue culture growth of the mammary glands of mice from a non-cancer line (D) after the addition of androsterone and 17-beta-estradiol to the culture medium]." 01/01/1984 - "For instance, the ratio of androsterone to alpha-cortolone is particularly effective in identifying women with a high rate of recurrence, and this is largely independent of pathological stage and tumor grade." 03/01/1986 - "Furthermore, the presence of significant amounts of endogenous androsterone and/or 5 alpha-androstane-3 alpha,17 beta-diol was demonstrated in both tumors by radioimmunoassay. " 10/01/1983 - "Sixteen of thirty-two tumor homogenates formed androsterone glucosiduronate (0.03-5.9%) from androsterone. " 06/01/1980 - "One tumor homogenate from an infiltrating lobular carcinoma converted 3H-delta 4-A to glucosiduronate metabolites (11%), of which androsterone, 6.4%; testosterone, 1.6%; and androstanediol, 0.6% predominated. "
4.	Anoxia (Hypoxia) 06/01/2006 - "Because of similarities in the relaxation of BCA to hypoxia (Po(2) = 8-10 Torr) and inhibitors of the pentose phosphate pathway (PPP) including 6-aminonicotinamide and epiandrosterone, we measured NADPH and NADP and found that hypoxia caused NADPH oxidation (decreased NADPH/NADP). " 07/01/2003 - "The steroids oestradiol, dehydroepiandrosterone and epiandrosterone (EPIA) were devoid of neuroprotective efficacy when present at 100 nM pre-, during and post-hypoxia. " 08/01/2013 - "Relaxation of BPA to G6PD inhibitors 6-aminonicotinamide (6-AN) and epiandrosterone (studied under hypoxia to minimize basal levels of NADPH oxidation and PKG1α dimerization) was associated with increased PKG1α dimerization and PKG-mediated vasodilator-stimulated phosphoprotein (VASP) phosphorylation. "
5.	Renal Insufficiency (Renal Failure) 02/17/1962 - "[The clearance of free and conjugated 17-hydroxycorticosteroids, of 17-ketosteroids, of androsterone, and of dehydroepiandrosterone, in chronic nephropathy with renal insufficiency. "

Related Drugs and Biologics

1.	Dehydroepiandrosterone (DHEA)
2.	17-Ketosteroids (17 Ketosteroids)
3.	Etiocholanolone
4.	cortol
5.	Erythromycin (Erycette)
6.	Chloramphenicol (Chloromycetin)
7.	Ascorbic Acid (Vitamin C)
8.	Steroids
9.	Estradiol (Estrace)
10.	17-Hydroxycorticosteroids

Related Therapies and Procedures

1.	Heterologous Transplantation (Xenotransplantation)
2.	Thyroidectomy
3.	Mastectomy (Mammectomy)
4.	Castration
5.	Aftercare (After-Treatment)