Androstanes

01/01/1984 - "A study of the efficacy of 5 alpha- and 5 beta-androstanes in chronic experimental aplastic anemia in mice."
01/01/1985 - "Historically oral androstanes have been helpful in the treatment of chronic aplastic anemia. "
01/01/1985 - "In the recovery phase of the aplastic anemia patients treated with immune suppression or androstanes the peripheral blood reflects an altered proliferation of the marrow stem cell. "
01/01/1985 - "The long-range survival in large cooperative groups of patients treated with androstanes have indicated that both severe and chronic aplastic anemia have had responses similar to immune suppressive therapy. "
12/01/1981 - "Effects of androstanes on aplastic anemia--a prospective study."

12/01/2013 - "In addition, several 17(E)-picolinylidene androstanes demonstrated selective antiproliferative activity against PC3 prostate cancer cells, which correlates with Abiraterone antiproliferative activity and predicted CYP17A1 binding affinities. "
12/01/2013 - "Virtual screening by molecular docking against clinical targets of steroidal anticancer drugs (ERα, AR, Aromatase and CYP17A1) suggests that 17(E)-picolinylidene, but not 17α-picolyl androstanes could specifically interact with CYP17A1 (17α-hydroxylase) with similar geometry and affinity as Abiraterone, a 17-pyridinyl androstane drug clinically used in the treatment of prostate cancer. "

12/06/1996 - "These 17beta-thioalkyl androstanes potently inhibit Sephadex-induced rat lung inflammation when administered directly into the airways. "

11/01/2011 - "Some steroids can be induced by epilepsy and/or treatment with antiepileptic drugs; however, there are still limited data available concerning this effect on the levels of other neuroactive steroid metabolites such as 3a-hydroxy-5a/b-reduced androstanes. "

04/01/1970 - "[Dehydration and acid catalysed of 17-beta, 17 a beta- diol in the series of 17-methyl a alpha D-homo androstanes]."