Anaplasmosis

09/01/1978 - "Efficacy of a new oxytetracycline formulation against clinical anaplasmosis."
01/01/1979 - "Efficacy of terramycin/LA-200 administered during the prepatent period of anaplasmosis."
01/01/1991 - "The objective of this study was to test the efficiency and acceptability of oxytetracycline hydrochloride (OTC) in anaplasmosis. "
11/15/1958 - "Laboratory studies of anaplasmosis in cattle treated with oxytetracycline."
07/01/1983 - "It was concluded that long-acting oxytetracycline can be used to eliminate the naturally acquired carrier state of anaplasmosis in cattle."

02/01/2000 - "The OK-tc may have potential to be used as antigen for development of an improved vaccine for anaplasmosis in the South Central United States."
10/22/2002 - "marginale shows promise for use as antigen in development of a new killed vaccine for anaplasmosis."
12/03/2001 - "marginale shows promise for use as antigen in development of a new killed vaccine for anaplasmosis."
11/01/2011 - "The current study demonstrates that the specificity of the recombinant major surface protein 5 (MSP5) antigen is not restricted to Anaplasma spp., which reduces the utility of the test for serological diagnosis of bovine anaplasmosis in regions where Ehrlichia sp. BOV2010-infected cattle might exist."
03/01/2007 - "Major surface protein 5 (Msp5) of Anaplasma marginale is highly conserved in the genus Anaplasma and the antigen used in a commercially available competitive enzyme-linked immunosorbent assay (cELISA) for serologic identification of cattle with anaplasmosis. "

12/01/2001 - "marginale is important in formulating control strategies and development of improved vaccines for anaplasmosis."
01/01/2013 - "This is a successful demonstration of epitope-based vaccines, and protection against anaplasmosis may be associated with elicitation of effector functions of humoral and cellular immune responses in murine model."
10/01/2003 - "These vaccines have been effective in preventing clinical anaplasmosis in cattle but have not blocked A. "
04/01/2015 - "marginale strain diversity as it relates geographic and ecological factors and to the development of effective vaccines for control of bovine anaplasmosis worldwide. "
10/01/2014 - "The results of the molecular characterization of the MSP1a can then be used as the basis for development of new and novel vaccines for anaplasmosis control in South Africa. "

11/01/1972 - "The inhibitory effect of imidocarb on experimental anaplasmosis in splenectomized calves."
10/01/1972 - "Elimination of the carrier state of bovine anaplasmosis with imidocarb."
05/01/1974 - "The chemotherapeutic efficacy of imidocarb dihydrochloride on concurrent bovine anaplasmosis and babesiosis. "
05/01/1974 - "The chemotherapeutic efficacy of imidocarb dihydrochloride on concurrent bovine anaplasmosis and babesiosis. "
07/01/1974 - "Immunity in bovine anaplasmosis after elimination of anaplasma marginale infections with imidocarb."

04/01/1990 - "Using this assay we found a significant reduction in bovine serum complement activity during the acute phase of anaplasmosis, and an increase in the sensitivity of the red blood cells (RBC) to bovine complement lysis in vitro. "
04/01/1966 - "Anaplasmosis: comparison of complement fixation methods and study of the cattle population of southern Alberta."
06/29/1998 - "Serologic diagnosis of anaplasmosis is currently done by the complement-fixation, ELISA, and card agglutination tests. "
10/01/1997 - "In order to learn more about the presence of bovine anaplasmosis in northern Veracruz state, México, paired blood and serum samples from 368 cattle were subjected to polymerase chain reaction (PCR) and complement-fixation test (CFt). "
04/01/1994 - "The prevalence of anaplasmosis in Oklahoma cattle was determined on the basis of the standardized Anaplasma marginale complement fixation test on 20,155 sera submitted to the Oklahoma Animal Disease Diagnostic Laboratory during a 15-year period. "

06/01/1981 - "The card agglutination test for anaplasmosis was improved so that bovine serum could be titrated for Anaplasma antibodies. "
09/01/2014 - "The prevalence of anti-B. miyamotoi antibodies among forestry workers was 10% (5.3-16.8%) and in patients with serologically unconfirmed but suspected human granulocytic anaplasmosis was 14.6% (9.0-21.8%); these were significantly higher compared with the seroprevalence in blood donors. "
09/01/2014 - "High seroprevalence of Borrelia miyamotoi antibodies in forestry workers and individuals suspected of human granulocytic anaplasmosis in the Netherlands."
02/01/2011 - "marginale and the role of wild ruminants in the epidemiology of bovine anaplasmosis are incompletely known owing to lack of published research, lack of validation of diagnostic tests for these species and cross-reaction of Anaplasma spp. antibodies in serologic tests. "
03/01/1984 - "Bovine anaplasmosis: in utero transmission and the immunologic significance of ingested colostral antibodies."

01/01/2010 - "Anaplasmosis is treated with doxycycline. "
11/01/2009 - "phagocytophilum occurs after natural infection requires additional study, with most reports suggesting that anaplasmosis is a self-limiting disease in dogs that responds well to a 2-week course of doxycycline therapy."
09/01/2012 - "Therapy was started with doxycycline for 10 days, and the wolf recovered within 24 hr. Clinical symptoms and temporary changes in blood parameters (thrombocytopenia, lymphopenia, mild anemia) in this wolf show high similarity to granulocytic anaplasmosis seen in dogs. "
08/01/2015 - "Rickettsial diseases include ehrlichiosis, anaplasmosis, and Rocky Mountain spotted fever, which are characterized by fever, headache, and possible rash and should be empirically treated with doxycycline while awaiting laboratory confirmation. "
02/01/1978 - "Relative efficacy of two oxytetracycline formulations and doxycycline in the treatment of acute anaplasmosis in splenectomized calves."

04/01/1957 - "A study of tetracycline dosage in cattle which are anaplasmosis carriers."
10/01/2013 - "Most reports suggesting that anaplasmosis is a self-limiting disease that responds well to a tetracycline therapy. "
01/04/2005 - "Tetracycline antimicrobials are currently the only drug used in the US for treatment of acute anaplasmosis. "
01/01/1989 - "The relationship between clinical anaplasmosis and other disease morbidity, nutritional supplementation, vaccinations, external and internal parasite control, tetracycline supplementation, reproductive management and use of veterinary services was assessed in 320 beef cow-calf herds in the Red River Plains and south-east areas of Louisiana. "
02/01/1979 - "The efficacy of a standard tetracycline, imidocarb and a new experimental long-acting tetracycline (T-200) in the treatment of anaplasmosis was examined in 5 groups of 9 nonsplenectomised, adult, 4-year-old, speyed cattle. "

02/01/1977 - "Low levels of chlortetracycline for anaplasmosis."
02/01/1977 - "Moderate to severe clinical signs of acute anaplasmosis occurred in the group 1 (previously uninfected) cattle, whereas only 1 of the chlortetracycline-treated cattle (group 2) and none of the vaccinated cattle (group 3) had clinical evidence of disease."
08/15/1965 - "CHLORTETRACYCLINE FOR ELIMINATION OF ANAPLASMOSIS IN CARRIER CATTLE."
05/15/1957 - "The prevention of anaplasmosis by feeding chlortetracycline."
10/01/1953 - "High-level aureomycin dosage in anaplasmosis."

06/25/2008 - "The outer membrane proteins of Anaplasma marginale have been the focus of research to obtain an improved vaccine against bovine anaplasmosis. "
04/01/2006 - "Anaplasma phagocytophilum, the etiologic agent of human granulocytic anaplasmosis, has a large paralog cluster (approximate 90 members) that encodes the 44-kDa major outer membrane proteins (P44s). "
06/01/2005 - "Genetic diversity of anaplasma species major surface proteins and implications for anaplasmosis serodiagnosis and vaccine development."
12/01/2007 - "The natural life cycle of Anaplasma phagocytophilum, an obligatory intracellular bacterium that causes human granulocytic anaplasmosis, consists of alternate infection of two distinct hosts, ticks and mammals, in which bacterial surface proteins are expected to have a critical role. "
04/01/2003 - "Major surface protein 2 (MSP2) is an immunodominant outer membrane protein of Anaplasma marginale and Anaplasma phagocytophilum pathogens that cause bovine anaplasmosis and human granulocytic ehrlichiosis, respectively. "

09/01/1978 - "A study was conducted to determine whether 1 intramuscular injection of an experimental long-acting oxytetracycline formulation was effective in treatment of induced acute anaplasmosis in cattle and to compare this with the drug response resulting from repeated treatments with an existing, approved oxytetracycline product. "

04/01/1984 - "Sixteen cattle serotest-negative for anaplasmosis with either no previous exposure (2 animals) or cleared 8 months earlier of their carrier state by chemotherapy (14 animals) were each exposed to Anaplasma marginale. "
04/14/2009 - "These findings demonstrate that FACS and electron microscopy are useful tools to screen new antimicrobials for the use in anaplasmosis chemotherapy."
02/01/1979 - "Chemotherapy of acute bovine anaplasmosis."
07/01/1947 - "Variables and constants in experimental bovine anaplasmosis and their relationship to chemotherapy."
11/01/2015 - "Major control measures for bovine anaplasmosis and tick-borne fever include rearing of tick-resistant breeds, endemic stability, breeding Anaplasma-free herds, identification of regional vectors, domestic/wild reservoirs and control, habitat modification, biological control, chemotherapy, and vaccinations (anaplasmosis and/or tick vaccination). "

09/01/1978 - "The response to treatment observed in the study animals indicates that 1 injection of the experimental formulation was equivalent to 2 daily injections of the 50 mg/ml product in treating animals with acute bovine anaplasmosis compared with infected nonmedicated control animals. "
07/01/1983 - "Bovine anaplasmosis: elimination of the carrier state with injectable long-acting oxytetracycline."
12/01/1982 - "Four injections of a long-acting oxytetracycline (20 mg/kg) were administered at 3-day intervals to 14 naturally infected anaplasmosis carrier cattle. "

04/01/2011 - "Antibiotic prophylaxis has been demonstrated to prevent Lyme disease, but similar studies have not investigated antibiotic prophylaxis for the prevention of anaplasmosis. "
04/01/2011 - "Given the additional risk of acquiring anaplasmosis from an I scapularis bite in the upper Midwest, this paper proposes an alternative regimen for antibiotic prophylaxis in this region."

05/26/1983 - "Artificial feeding of adult and nymphal Dermacentor andersoni (Acari: Ixodidae) during studies on bovine anaplasmosis."