Amphibian Venoms

Venoms produced by frogs, toads, salamanders, etc. The venom glands are usually on the skin of the back and contain cardiotoxic glycosides, cholinolytics, and a number of other bioactive materials, many of which have been characterized. The venoms have been used as arrow poisons and include bufogenin, bufotoxin, bufagin, bufotalin, histrionicotoxins, and pumiliotoxin.

Also Known As:

Networked: 77 relevant articles (5 outcomes, 11 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Duan, Jinao: 5 articles (08/2021 - 01/2012)
2.	Ma, Hongyue: 5 articles (08/2021 - 01/2012)
3.	Zhou, Jing: 5 articles (08/2021 - 01/2012)
4.	Wu, Qinan: 3 articles (08/2021 - 03/2012)
5.	Yue, Qingxi: 3 articles (01/2021 - 01/2016)
6.	Wang, Ying: 3 articles (01/2013 - 01/2012)
7.	Jiang, Jiejun: 3 articles (07/2012 - 01/2012)
8.	Xu, Huiqin: 3 articles (07/2012 - 01/2012)
9.	Zhan, Zhen: 3 articles (07/2012 - 01/2012)
10.	Zhang, Junfeng: 3 articles (07/2012 - 01/2012)

Related Diseases

1.	Poisoning 04/01/2003 - "The treatment approach to patients with suspected toad venom poisoning is described." 04/01/2003 - "Toad venom poisoning is similar to digitalis toxicity and carries a high mortality. " 01/01/2009 - "In the past, toad-venom poisoning has been reported from ingestion of toad soup, Kyushin and aphrodisiac pills, but poisoning from toad eggs is observed for the first time. " 03/01/2007 - "In the past, toad-venom poisoning had been reported from ingestion of toad soup, Kyushin and aphrodisiac pills, but the poisoning from toad eggs is observed for the first time. " 04/01/2003 - "Toad venom poisoning: resemblance to digoxin toxicity and therapeutic implications."
2.	Neoplasms (Cancer) 07/01/2021 - "Until the last decade, an increasing number of studies have documented that toad venom is a source of lead compound(s) for the development of potential cancer treatment drugs. " 09/18/2020 - "Aim of the study: To identify the bioactive compounds and pharmacophores originating from toad venom based on analyzing spectrum-effect relationship by chemometrics and to explore the anti-cancer mechanism primarily. " 08/10/2020 - "Toad venoms are a rich source of potentially pharmaceutically active compounds and studies have highlighted their possible effect on cancer cells. " 07/01/2021 - "This review summarizes the chemical constituents of toad venom, analyzing their anticancer activities and molecular mechanisms for cancer treatments. " 07/01/2018 - "In total, 17 components in toad venom were discovered to interact with the target cancer cells. "
3.	Hemorrhage 01/01/1947 - "The action of Toad Venom (Bufo Bufo Bufo) on Bleeding and Coagulation Times in Rabbits" 01/01/2021 - "Bee venom therapy is effective in treating musculoskeletal pain, snake venom therapy is effective in controlling bleeding during surgery, and toad venom therapy is effective in cancer treatment. "
4.	Musculoskeletal Pain 01/01/2021 - "Bee venom therapy is effective in treating musculoskeletal pain, snake venom therapy is effective in controlling bleeding during surgery, and toad venom therapy is effective in cancer treatment. "
5.	Ulcer 01/01/2014 - "Cinobufagin and resibufogenin are two major effective bufadienolides of Chan su (toad venom), which is a Chinese medicine obtained from the skin venom gland of toads and is used as a cardiotonic and central nervous system (CNS) respiratory agent, an analgesic and anesthetic, and as a remedy for ulcers. "

Related Drugs and Biologics

1.	Digoxin (Digitek)
2.	Immunoglobulin Fab Fragments
3.	bufalin
4.	Bufanolides
5.	chan su (ChanSu)
6.	Steroids
7.	Analgesics (Analgesic Drugs)
8.	bufogenin
9.	cinobufagin
10.	Venoms

Related Therapies and Procedures

1.	Therapeutics
2.	Chinese Traditional Medicine (Traditional Chinese Medicine)
3.	Intravenous Injections
4.	Analgesia
5.	Traditional Medicine (Folk Remedies)