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Amoxicillin (Wymox)

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A broad-spectrum semisynthetic antibiotic similar to AMPICILLIN except that its resistance to gastric acid permits higher serum levels with oral administration.

Also Known As:

Wymox; Amoxicilline; Amoxil; Trimox; Actimoxi; Amoxicillin monopotassium salt; Amoxicillin monosodium salt; Amoxicillin trihydrate; Amoxicillin, (R*)-isomer; Amoxycillin; BRL-2333; Clamoxyl; Clamoxyl G.A.; Clamoxyl parenteral; Clariana Brand of Amoxicillin; Penamox; Pfizer Brand of Amoxicillin Sodium Salt; Polymox; SmithKline Beecham Brand of Amoxicillin Sodium Salt; Amoxicillin Clariana Brand; BRL 2333; BRL2333; G.A., Clamoxyl; parenteral, Clamoxyl; trihydrate, Amoxicillin; Hydroxyampicillin; 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((amino(4-hydroxyphenyl)acetyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta(S*)))-

Networked: 3709 relevant articles (522 outcomes, 640 trials/studies)

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Drug Context: Research Results

Experts

1.	Brook, Itzhak: 17 articles (04/2015 - 04/2002)
2.	Thea, Donald M: 11 articles (10/2015 - 09/2004)
3.	Jacobs, Michael R: 10 articles (12/2008 - 10/2002)
4.	Mayorga, Cristobalina: 9 articles (11/2015 - 10/2006)
5.	Qazi, Shamim: 9 articles (10/2015 - 03/2003)
6.	Torres, M J: 9 articles (08/2015 - 09/2001)
7.	Feres, Magda: 9 articles (09/2014 - 10/2008)
8.	Gober, Alan E: 9 articles (05/2009 - 04/2002)
9.	Blanca, M: 8 articles (08/2015 - 09/2001)
10.	Faveri, Marcelo: 8 articles (09/2014 - 10/2008)

Related Diseases

1.	Infection 06/01/2006 - "Amoxicillin-based therapies are highly effective for the treatment of Helicobacter pylori infections, but the efficacy may decrease as the incidence of amoxicillin resistance is increasing. " 01/01/2012 - "The infection resolved completely after twelve weeks of treatment with oral amoxicillin. " 08/01/2005 - "In conclusion, the efficacy of these two dosage regimens of amoxycillin was not significantly different in treatment of acute Ap-infection in pigs." 07/01/2001 - "The PA infection was treated successfully with amoxicillin." 05/01/1984 - "Similarly, those with infections caused by amoxicillin-susceptible organisms were cured at a significantly higher rate than those with infections caused by resistant organisms (85 versus 50%; P less than 0.001). "
2.	Otitis Media 01/01/2011 - "Watchful waiting, followed by amoxicillin treatment, if necessary, is the best first-line treatment for acute otitis media in children aged six months or older." 12/01/1989 - "Amoxicillin is the standard of therapy for infants and children with acute otitis media, because it is safe and effective for most of the causative bacterial pathogens. " 08/01/2004 - "Developing community-specific recommendations for first-line treatment of acute otitis media: is high-dose amoxicillin necessary?" 05/01/2003 - "Bacteriologic and clinical efficacy of high dose amoxicillin for therapy of acute otitis media in children." 12/01/1986 - "Because reduction in division of the amoxicillin dose caused no significant difference in the efficacy of antibiotic treatment of acute otitis media in infants and children, we think that this simplified scheme of therapy can routinely be used in clinical practice and thus improve compliance to antibiotic administration."
3.	Pneumonia (Pneumonitis) 12/01/2007 - "Oral amoxicillin is effective for most children admitted to hospital with pneumonia (all but those with the most severe disease who were excluded from this study). " 09/01/2011 - "On review after 48 h, if improved, the child may be sent home on oral amoxicillin for 5 more days; if not, it is treated as very severe pneumonia. " 12/01/2013 - "In summary, pneumococcal susceptibility to amoxicillin remains high throughout Africa, and amoxicillin can be effectively and safely used as first-line treatment for childhood pneumonia. " 07/01/2014 - "Oral amoxicillin was also found to be effective in non-severe pneumonia as well. " 01/01/2013 - "Oral amoxicillin administered either in hospital or community setting is effective in treatment of severe pneumonia and is not inferior to the standard treatment. "
4.	Respiratory Tract Infections (Respiratory Tract Infection) 01/01/2015 - "Estimate the efficacy of amoxicillin for acute uncomplicated lower-respiratory-tract infection (LRTI) in primary care and demonstrate the use of randomisation-based efficacy estimators. " 04/01/2002 - "To compare the efficacy of amoxicillin vs placebo in patients with an acute upper respiratory tract infection and purulent rhinorrhea. " 01/01/1981 - "Prospective clinical trial on the efficacy of amoxycillin administered twice or four times daily in children with respiratory tract infections." 11/01/1986 - "The present study compares the clinical efficacy and side-effects of amoxycillin in two groups of children at the age of six years or less randomly assigned to amoxycillin therapy 40 mg/kg/day either two or three times daily for the clinical diagnosis of acute respiratory tract infections. " 09/01/2014 - "The most widely prescribed antibiotic for the treatment of upper respiratory tract infections in children during the three years was amoxicillin (34.63; 32.50 and 31.00 defined daily dose/1000 inhabitants/day in 2008, 2009 and 2010, respectively). "
5.	Urinary Tract Infections (Urinary Tract Infection) 12/01/1982 - "We conclude that a single 3 g dose of amoxicillin, with follow-up urine culture, provides safe and effective management for acute uncomplicated urinary tract infections in nonpregnant women." 02/23/1978 - "Efficacy of single-dose and conventional amoxicillin therapy in urinary-tract infection localized by the antibody-coated bacteria technic." 02/01/2006 - "The data collected were compared with those of a previous trial performed in the same setting and documenting the effectiveness and advantages associated with the use of amoxicillin against community-acquired uncomplicated urinary tract infections (UTI). " 06/01/1983 - "A comparative trial of amoxycillin 3g bd and conventional amoxycillin therapy in the treatment of urinary tract infection in a general practice population." 02/01/1983 - "[Clinical study on long acting amoxicillin in urinary tract infection]."

Related Drugs and Biologics

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2.	Clarithromycin (Biaxin)
3.	Omeprazole (Esomeprazole)
4.	Metronidazole (Metric)
5.	Penicillins (Penicillin)
6.	Amoxicillin-Potassium Clavulanate Combination (Co-amoxiclav)
7.	Anti-Bacterial Agents (Antibiotics)
8.	Azithromycin (Zithromax)
9.	Cefaclor (Ceclor)
10.	Erythromycin (Erycette)

Related Therapies and Procedures

1.	Aftercare (After-Treatment)
2.	Injections
3.	Drug Therapy (Chemotherapy)
4.	Retreatment
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