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Amodiaquine (Camoquin)

Subscribe to New Research on Amodiaquine

A 4-aminoquinoline compound with anti-inflammatory properties.

Also Known As:

Camoquin; Amodiachin; Amodiaquin; Amodiaquine Hydrochloride; Camoquine; Flavoquine; Roussel Brand of Amodiaquine Hydrochloride; Hydrochloride, Amodiaquine; Phenol, 4-((7-chloro-4-quinolinyl)amino)-2-((diethylamino)methyl)-

Networked: 589 relevant articles (133 outcomes, 128 trials/studies)

Relationship Network

Drug Context: Research Results

Heterocyclic Compounds: 60
- 2-Ring Heterocyclic Compounds
  - Quinolines: 92
    - Aminoquinolines: 11
      - Amodiaquine: 589
        artesunate drug combination amodiaquine: 33
        desethylamodiaquine: 13
        amodiaquine quinoneimine: 1
        2',6'-difluoroamodiaquine
        4'-dehydroxy-4'-fluoroamodiaquine
        5-(7-chloroquinolin-4-ylamino)-2-diethylaminomethylphenol
        7-chloro-4-(4'-fluoro-5'-((diethylamino)methylanilino))quinoline
        7-chloro-4-(4'-hydroxy-3'-(2''-(ethylamino)ethanol)methylanilino)quinoline
        N-tert-butylisoquine

Experts

1.	Dorsey, Grant: 24 articles (01/2015 - 12/2002)
2.	Rosenthal, Philip J: 23 articles (08/2015 - 12/2002)
3.	Sowunmi, Akintunde: 18 articles (01/2015 - 05/2007)
4.	Basco, Leonardo K: 14 articles (01/2015 - 01/2002)
5.	Kamya, Moses R: 14 articles (01/2015 - 12/2002)
6.	Gbotosho, Grace O: 14 articles (01/2014 - 05/2007)
7.	Happi, Christian T: 14 articles (01/2014 - 05/2007)
8.	Greenwood, Brian: 13 articles (08/2015 - 10/2006)
9.	Olliaro, Piero: 12 articles (01/2015 - 10/2005)
10.	Chandramohan, Daniel: 12 articles (03/2011 - 10/2006)

Related Diseases

1.	Falciparum Malaria (Plasmodium falciparum Malaria) 01/01/2008 - "The objective of the study was to determine the efficacy of amodiaquine against falciparum malaria in neighbouring rural and urban areas of north-western Burkina Faso. " 02/01/2003 - "We conducted a randomized, single-blinded trial to compare the efficacy of SP monotherapy with combinations of SP and either CQ or amodiaquine (AQ) for the treatment of uncomplicated falciparum malaria in patients over 6 months of age in Kampala, Uganda. " 01/01/2008 - "Efficacy of amodiaquine in the treatment of uncomplicated falciparum malaria in young children of rural north-western Burkina Faso." 09/01/2004 - "Short report: lack of prediction of amodiaquine efficacy in treating Plasmodium falciparum malaria by in vitro tests." 11/01/2002 - "Efficacy of amodiaquine for uncomplicated Plasmodium falciparum malaria in Harper, Liberia."
2.	Malaria 10/01/2003 - "Currently, successful malaria treatment depends primarily upon the efficacy of SP, and of amodiaquine, which is either a component of first-line treatment, or the second line drug. " 09/01/2003 - "Rapid clearance of Plasmodium falciparum hyperparasitaemia after oral amodiaquine treatment in patients with uncomplicated malaria." 04/01/2007 - "[Therapeutic efficacy of amodiaquine against uncomplicated malaria in Madagascar]." 11/01/1999 - "Amodiaquine remains effective for treating uncomplicated malaria in west and central Africa." 06/01/2006 - "Amodiaquine plus SP remains an efficacious, affordable and safe option for treating malaria in certain settings."
3.	Infection 05/01/2008 - "In this study, we analyzed the effects of baseline parameters on the initial parasite elimination rate and the risk of subsequent recrudescence as a marker for incompletely eliminated asexual blood-stage parasites in pediatric patients with uncomplicated Plasmodium falciparum infection treated with amodiaquine in a high-transmission area. " 10/01/1992 - "Amodiaquine cleared 209 (80%) of PROG's total infections and 224 (81%) for CQ-cohort, and significantly reduced the infection load among clearance failures. " 10/01/1979 - "Some amodiaquine congeners shown to be effective in experimental infections against adult filarial worms may prove to have a higher chemotherapeutic index than amodiaquine against W. " 01/01/2000 - "Randomised and quasi-randomised trials comparing amodiaquine with other treatment for uncomplicated malarial infections in adults and children. " 11/01/2012 - "Amodiaquine treatment reduced the risk of recurrent infections from 22.2% to 7.4% at day 35. "
4.	Fever (Fevers) 05/31/2003 - "The protective efficacy of intermittent amodiaquine treatment in prevention of malarial fevers and anaemia was 64.7% (95% CI, 42.4-77.2) and 67.0% (95% CI, 34.5-83.4), respectively. " 05/31/2003 - "Effect of intermittent treatment with amodiaquine on anaemia and malarial fevers in infants in Tanzania: a randomised placebo-controlled trial." 01/01/2009 - "Amodiaquine was the most effective on fever. " 01/01/2008 - "Young age, parasitaemia >/=500 parasites/microl; onset of parasitaemia after day 14, and treatment with amodiaquine were the main variables associated with higher risk of developing fever. " 11/02/1996 - "The time to parasitological clearance was similar in the two groups; fever clearance times were significantly shorter with amodiaquine. "
5.	Parasitemia 08/01/1991 - "Yet 15.5% of students receiving amodiaquine harbored parasites with RI resistance (recurrence of parasitemia within 7 days), especially delayed RI resistance. " 01/01/1987 - "In a hospital study, all eight patients receiving chloroquine cleared their parasitemia by day 6, but six of eight patients receiving amodiaquine failed to clear parasitemia and in four patients there was no response at all (RIII resistance); this difference was significant (P less than 0.01). " 09/01/2005 - "The authors recommend that the treatment to be used in Abie must be firstly amodiaquine followed by sulfadoxine-pyrimethamine in cases where there is persistent asymptomatic parasitemia." 06/01/1992 - " Even though the 3 remaining cases with parasitemia received amodiaquine treatment, clinicians administered Fansidar, resulting in a clearing of parasitemia in 7 days. " 05/01/1978 - "A 5-day regimen of primaquine, with dosages based on an adult dose of 15 mg per day, produced a substantial reduction in the numbers of patients experiencing renewed parasite activity and in the number of parasitemias experienced by the group during 9 mo of posttreatment observation, when compared with patients treated only with amodiaquine. "

Related Drugs and Biologics

1.	artesunate
2.	sulfadoxine-pyrimethamine (Fansidar)
3.	Chloroquine (Aralen)
4.	artemether
5.	lumefantrine
6.	artemisinine (artemisinin)
7.	piperaquine
8.	Quinine (Quinson)
9.	dihydroquinghaosu (dihydroartemisinin)
10.	Pyrimethamine (Daraprim)

Related Therapies and Procedures

1.	Traditional Medicine (Folk Remedies)
2.	Chemoprevention
3.	Aftercare (After-Treatment)
4.	Drug Therapy (Chemotherapy)
5.	Liver Transplantation