Ammonia

09/01/2003 - "Serum biochemical parameters and blood ammonia levels, liver histology, stage of hepatic encephalopathy, and survival were statistically significantly improved in TAA-intoxicated and rG-CSF-treated rats compared to TAA-intoxicated and saline-treated ones. "
07/01/2014 - "Ammonia levels were slightly increased without exacerbating hepatic encephalopathy, and the protein nutrition state consequently improved. "
12/01/2003 - "pylori has been shown to improve the blood ammonia levels and hepatic encephalopathy."
06/01/2013 - "Data from both animal and human studies sustain that there is a synergistic effect between systemic oxidative stress, and ammonia that is implicated in the pathogenesis of hepatic encephalopathy."
06/01/2011 - "However, previous studies on the relationship between ammonia and the severity of hepatic encephalopathy have yielded variable results. "

05/01/2001 - "An improved understanding of the metabolism of ammonia and neurological consequences of hyperammonemia will assist the nephrologist in providing optimal care for this high-risk patient population."
04/28/2015 - "In conclusion, the present observations highlight the importance of hepatic GS for maintenance of ammonia homeostasis and establish the liver-specific GS KO mouse as a model with which to study effects of chronic hyperammonemia. "
03/01/2014 - "Our work attempts to reproduce an increase in rat cerebral ammonia level, study the hyperamonemic animals' performance of two learning tasks, an allocentric (ALLO) and a cue guided (CG) task, and elucidate the contribution of hyperammonemia to the differential energy requirements of the brain limbic system regions involved in these tasks. "
10/01/2008 - "In this study, we aimed to modulate hyperammonemia in three rodent models by administration of wild-type Lactobacillus plantarum, a genetically engineered ammonia hyperconsuming strain, and a strain deficient for the ammonia transporter. "
07/01/1996 - "Because dialysis has been recommended for acute hyperammonemia in other conditions, we have conducted a study to analyze the determinants of ammonia clearance with the use of a single-pass dialyzer. "

09/01/1998 - "The results showed that survival as well as porcine hepatocyte integrity improved, the onset of coma delayed, and the ammonia levels decreased in LIS rats of the 38 hour group compared to the 14 hour group, but no statistically significant differences were observed. "
06/01/1989 - "Studies of ammonia loading: effects of rate of delivery and enhanced removal of NH4 on blood levels of ammonia and coma induction."
01/01/1981 - "Previous studies have implicated the ascending reticular activating system (RAS) as playing a vital role in ammonia induced coma. "
06/01/2015 - "IHA is characterized by a sudden increase in plasma ammonia levels in the absence of any identifiable causes, which mostly results in intractable coma and high mortality. "
08/15/2013 - "The main prognostic factors are, irrespective of the underlying cause, the duration of the hyperammonemic coma and the extent of ammonia accumulation. "

08/01/2011 - "Significant reduction in blood ammonia levels and endotoxin levels were reported in parallel to improvement of liver disease. "
03/01/2009 - "Significant reduction in blood ammonia levels and endotoxin levels were reported in parallel to improvement of liver disease. "
06/01/1995 - "T1WSE contrast measurements of the globus pallidus were increased with elevations in blood ammonia levels (p < 0.05) and with the severity of liver dysfunction, when graded according to the Pugh's score (p < 0.05) Those patients with the worst liver injury (Child's grade C) had significantly greater T1WSE pallidal contrast measurements (p < 0.05) than those patients with minimal liver injury (Child's grade A). "
04/01/1990 - "The increased exposure of patients with chronic liver disease to ammonia while performing an identical workload results from an impaired clearance of ammonia plus, possibly, an increased generation of ammonia in muscle working at a higher intensity. "
01/01/1983 - "This study reports the relevance of plasma and erythrocyte ammonia concentrations in patients with liver disease. "

03/01/2003 - "The 3 treatments reduced HE, but with different efficacy: patients of group R and RL significantly (p<0.05) documented a faster improvement in HE degree, a higher percentage of patients which normalized mental state and NCT, a faster improvement of asterixis and a longer persistence of normal ammonia levels than patients of group L. "
07/01/1981 - "Both treatments significantly improved the frequency of asterixis, ammonia blood levels, and electroencephalograms. "
05/01/1978 - "In addition, there was equivalent improvement in asterixis, in the performance of the Number Connection Test, in the electroencephalographic pattern, and in arterial ammonia concentration. "
06/01/1989 - "The PSE index (mental state, EEG, asterixis, Raitan test, and ammonia) was assessed in each patient on entry to the study and every three months during treatment. "
10/01/2009 - "Four variously weighted components of PSE were graded on a scale of 0 to 4: (1) mental state, (2) asterixis, (3) number connection test, and (4) arterial blood ammonia. "