HOME PRODUCTS SERVICES COMPANY CONTACT FAQ

Aminolevulinic Acid (Levulan)

Subscribe to New Research on Aminolevulinic Acid

A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.

Also Known As:

Levulan; 5 Aminolevulinate; 5-Aminolaevulinate; 5-Aminolevulinate; Aminolevulinic Acid Hydrochloride; Bertek Brand of Aminolevulinic Acid Hydrochloride; Delta-Aminolevulinic Acid; 5 Aminolaevulinate; Acid Hydrochloride, Aminolevulinic; Acid, Aminolevulinic; Acid, Delta-Aminolevulinic; Delta Aminolevulinic Acid; Hydrochloride, Aminolevulinic Acid; Pentanoic acid, 5-amino-4-oxo-

Networked: 562 relevant articles (42 outcomes, 50 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1.	Hasan, Tayyaba: 10 articles (01/2015 - 03/2006)
2.	Wilson, Brian C: 9 articles (12/2015 - 11/2003)
3.	Pogue, Brian W: 8 articles (11/2015 - 05/2002)
4.	Maytin, Edward V: 7 articles (11/2015 - 05/2009)
5.	Stummer, Walter: 7 articles (03/2015 - 03/2007)
6.	Taketani, Shigeru: 5 articles (09/2014 - 12/2005)
7.	Valdés, Pablo A: 5 articles (07/2012 - 03/2010)
8.	Roberts, David W: 5 articles (07/2012 - 03/2010)
9.	Paulsen, Keith D: 5 articles (07/2012 - 03/2010)
10.	Bissonnette, Robert: 5 articles (11/2008 - 07/2002)

Related Diseases

1.	Acne Vulgaris 08/01/2000 - "Topical aminolevulinic acid plus red light is an effective treatment of acne vulgaris, associated with significant side-effects. " 08/01/2000 - "There was clinical and statistically significant clearance of inflammatory acne by aminolevulinic acid plus red light, for at least 20 wk after multiple treatments and 10 wk after a single treatment. " 08/01/2000 - "Potentially, aminolevulinic acid plus red light may be useful for some patients with acne." 08/01/2000 - "Each of 22 subjects with acne on the back was treated in four sites with aminolevulinic acid plus red light, aminolevulinic acid alone, light alone, and untreated control. " 07/01/2009 - "In this African-American patient, 20% aminolevulinic acid/blue-light photodynamic therapy was effective in treating facial acne vulgaris."
2.	Actinic Keratosis 09/01/2014 - "The effect of multiple sequential light sources to activate aminolevulinic Acid in the treatment of actinic keratoses: a retrospective study." 09/01/2010 - "Eighteen patients with actinic keratoses of the face or upper limbs received an application of a 20% delta-aminolevulinic acid cream and were submitted to diode light irradiation at a wavelength of 630 nm. A total of 328 actinic keratoses were treated, obtaining complete cure in 210 (64.0%) after 24 weeks. " 05/01/2008 - "Intense pulsed light with methyl-aminolevulinic acid for the treatment of actinic keratoses." 02/01/2007 - "Aminolevulinic acid and photodynamic combination therapy in the treatment of actinic keratoses: caring for the patient." 01/01/2006 - "Broad-band blue light and red light have been studied extensively, the former achieving Food and Drug Administration approval in combination with topical aminolevulinic acid for the treatment of actinic keratosis in 1997. "
3.	Basal Cell Carcinoma (Rodent Ulcer) 06/01/2000 - "Delta-aminolevulinic acid in superficial basal cell carcinomas and normal skin-a microdialysis and perfusion study." 09/01/2007 - "Aminolevulinic acid (ALA) and light irradiation is a treatment option in basal cell carcinomas (BCC). " 07/01/2004 - "Photodynamic therapy with delta-aminolevulinic acid using red light (approximately 630 nm) sources has been reported as effective in treatment of superficial and small nodular basal cell carcinomas. " 01/01/2000 - "This study was conducted to assess the efficacy of aminolevulinic acid-based photodynamic treatment for residual or recurrent basal cell carcinomas after radiotherapy. " 07/01/2013 - "Aminolevulinic Acid-photodynamic therapy of Basal cell carcinoma and factors affecting the response to treatment: a clinical trial."
4.	Neoplasms (Cancer) 04/01/2003 - "This study was performed to characterize the transport of the endogenous photosensitizer delta-aminolevulinic acid in tumor cells of the extrahepatic biliary duct. " 01/01/2015 - "Aminolevulinic Acid-Based Tumor Detection and Therapy: Molecular Mechanisms and Strategies for Enhancement." 07/01/2012 - "Five-aminolevulinic acid (5-ALA) has been shown to accumulate in malignant tumor tissue. " 05/01/2011 - "Only two prior case reports in the literature have used fluorescent diagnosis, with aminolevulinic acid, to define tumor margins. " 03/01/2010 - "delta-Aminolevulinic acid (ALA) is used in cancer patients for photodynamic diagnosis or therapy. "
5.	Melanoma (Melanoma, Malignant) 04/01/1999 - "Photodynamic therapy with delta-aminolevulinic acid can eradicate eye-close non-melanoma skin malignancies without compromising the function of the eyelids. " 04/01/1999 - "Photodynamic therapy utilising topical delta-aminolevulinic acid in non-melanoma skin malignancies of the eyelid and the periocular skin." 10/01/2011 - "Pre-surgical mapping of cutaneous non-melanoma carcinoma using topical methyl aminolevulinic acid." 01/01/2000 - "Photodynamic therapy of murine colon cancer and melanoma using systemic aminolevulinic acid as a photosensitizer." 07/01/2000 - "Photodynamic therapy (PDT) with topical d-aminolevulinic acid (ALA) has become a therapeutic option of growing interest for superficial non-melanoma precancerous and malignant lesions. "

Related Drugs and Biologics

1.	1-phenyl-3,3-dimethyltriazene (PDT)
2.	protoporphyrin IX
3.	Porphyrins
4.	Porphobilinogen
5.	temoporfin
6.	Photosensitizing Agents (Photosensitizers)
7.	Hydroxymethylbilane Synthase (Porphobilinogen Deaminase)
8.	Calcitriol (Calcijex)
9.	motexafin gadolinium
10.	tetraphenylporphyrin

Related Therapies and Procedures

1.	Photochemotherapy (Photodynamic Therapy)
2.	Radiotherapy
3.	Drug Therapy (Chemotherapy)
4.	Gas Lasers
5.	Solid-State Lasers