Renal Aminoacidurias (Aminoaciduria, Renal)

A group of inherited kidney disorders characterized by the abnormally elevated levels of AMINO ACIDS in URINE. Genetic mutations of transport proteins result in the defective reabsorption of free amino acids at the PROXIMAL RENAL TUBULES. Renal aminoaciduria are classified by the specific amino acid or acids involved.

Also Known As:

Networked: 6 relevant articles (0 outcomes, 2 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Hypophosphatemia
2.	Familial Hypophosphatemia (Phosphate Diabetes)
3.	Glycosuria
4.	Fanconi Syndrome (Syndrome, Fanconi)
5.	Renal Tubular Acidosis (Distal Renal Tubular Acidosis)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Renal Aminoacidurias:

1.	Amino AcidsFDA Link 09/01/1952 - "Renal aminoaciduria; report of two cases, with studies of amino acid excretion patterns." 01/01/1957 - "[Dynamics of amino acid metabolism and renal aminoaciduria]." 02/01/1982 - "Other disorders occur due to loss of affinity or capacity of the cellular active transport systems for specific solutes, such as amino acids (renal aminoacidurias), glucose (renal glycosurias) and bicarbonate (proximal renal tubular acidosis), or for all solutes (Fanconi syndrome). "
2.	Uric Acid (Urate)IBA 09/28/1974 - "Renal clearance studies showed that the hypouricaemia was associated with an increased urate clearance, renal aminoaciduria, and an episodic increase in phosphate clearance. "
3.	Phosphates (Orthophosphate)IBA 09/28/1974 - "Renal clearance studies showed that the hypouricaemia was associated with an increased urate clearance, renal aminoaciduria, and an episodic increase in phosphate clearance. "
4.	Glucose (Dextrose)FDA LinkGeneric 02/01/1982 - "Other disorders occur due to loss of affinity or capacity of the cellular active transport systems for specific solutes, such as amino acids (renal aminoacidurias), glucose (renal glycosurias) and bicarbonate (proximal renal tubular acidosis), or for all solutes (Fanconi syndrome). "
5.	EnzymesIBA 12/15/1988 - "These results indicated that the lack of enzyme activity caused a specific renal aminoaciduria. "
6.	D-Amino-Acid Oxidase (D-Amino Acid Dehydrogenase)IBA 12/15/1988 - "Lack of D-amino-acid oxidase activity causes a specific renal aminoaciduria in the mouse."
7.	Blood Proteins (Serum Proteins)IBA 12/15/1995 - "The characteristic manifestations of this nephrotoxicity include phosphaturia and hypophosphatemia, glycosuria, aminoaciduria, renal tubular acidosis, and urinary loss of low molecular weight serum proteins. "
8.	Bicarbonates (Hydrogen Carbonate)IBA 02/01/1982 - "Other disorders occur due to loss of affinity or capacity of the cellular active transport systems for specific solutes, such as amino acids (renal aminoacidurias), glucose (renal glycosurias) and bicarbonate (proximal renal tubular acidosis), or for all solutes (Fanconi syndrome). "