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Amidines

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Networked: 11 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 58
- Amidines: 11

Experts

1.	Wintachai, Phitchayapak: 1 article (03/2015)
2.	Basmadjian, Christine: 1 article (03/2015)
3.	Smith, Duncan R: 1 article (03/2015)
4.	Ubol, Sukathida: 1 article (03/2015)
5.	Thuaud, Frédéric: 1 article (03/2015)
6.	Désaubry, Laurent: 1 article (03/2015)
7.	Roytrakul, Sittiruk: 1 article (03/2015)
8.	Menna-Barreto, Rubem F S: 1 article (01/2011)
9.	Silva, Cristiane F: 1 article (01/2011)
10.	Silva, Patricia B: 1 article (01/2011)

Related Diseases

1.	Neoplasms (Cancer) 03/01/2015 - "Recently, synthetic sulfonyl amidines and flavaglines (FLs), a class of naturally occurring plant compounds with potent anti-cancer and cytoprotective and neuroprotective activities, have been shown to interact directly with prohibitin. " 11/01/1997 - "Inhibition of tumor growth and polyamine uptake by tetracyclic amidines bearing a putrescine moiety." 11/01/1997 - "Potential mechanisms include: a) lower intracellular polyamine levels reduces polyamine DNA-stabilizing functions, increasing accessibility for DNA-binding drugs; b) DFMO enhances the polyamine uptake system in tumor cells, increasing the entry of tetracyclic amidines bearing a putrescine moiety as well as their accessibility to final DNA-binding sites. " 06/01/1986 - "Moreover, the data reported here allowed us to clarify the inhibition mechanism (in vitro) of TAPP-H on blood coagulation, induced by the "cancer coagulation factor" produced by the Walker carcinoma in Wistar rats and on the fibrinogen-to-fibrin conversion, and to identify some serine proteinases which act as targets for aromatic tetra-amidines."
2.	Chagas Disease (American Trypanosomiasis) 01/01/2011 - "Experimental Chemotherapy for Chagas Disease: A Morphological, Biochemical, and Proteomic Overview of Potential Trypanosoma cruzi Targets of Amidines Derivatives and Naphthoquinones." 11/01/2007 - "Since the chemotherapy for Chagas' disease is still an unsolved problem and previous reports on diamidines and related analogues show that they have high levels of activity against Trypanosoma cruzi infection both in vitro and in vivo, our present aim was to evaluate the cellular effects in vitro of three reversed amidines (DB889, DB702, and DB786) and one diguanidine (DB711) against both amastigotes and bloodstream trypomastigotes of T. "
3.	Ganglion Cysts (Ganglion) 11/01/1962 - "Action of indole alkylamines and amidines on the inferior mesenteric ganglion of the cat."
4.	Paramyxoviridae Infections (Parainfluenza) 02/01/1978 - "New derivatives (esters, amides, nitriles, amidines, thiosemicarbazones and guanylhydrazones) of 1H-benz[e]indene-2,3-dihydro-5-methyl-1-oxo-3-carboxylic acid and 1H-benz[e]indene-2,3-dihydro-7-methyl-3-oxo-1-carboxylic acid were prepared and tested for antiviral activities in vitro against vaccinia virus, HID stock and parainfluenza type 3 virus, HA-I/CR-8 stock. "
5.	Radiation Injuries (Radiation Sickness) 05/01/1965 - "[ON THE COMBINED USE OF A CHEMICAL PROTECTIVE MIXTURE OF CYSTEAMINE AND AMIDINES WITH BONE MARROW TRANSPLANTATION IN ACUTE RADIATION INJURY]."

Related Drugs and Biologics

1.	indole
2.	Serine Proteases (Serine Protease)
3.	Thiosemicarbazones
4.	Putrescine
5.	Peptide Hydrolases (Proteases)
6.	Nitriles
7.	Naphthoquinones
8.	Fibrinogen (Factor I)
9.	Fibrin
10.	Esters

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Bone Marrow Transplantation (Transplantation, Bone Marrow)