Altitude Sickness (Mountain Sickness)

01/01/2008 - "The efficacy of acetazolamide against acute mountain sickness, however, was significant with a 21.9% incidence in the placebo group compared to 10.2 % in the acetazolamide group (p < 0.01). "
10/01/1992 - "Evidence that Acetazolamide is beneficial for pulmonary oedema or cerebral oedema is scanty because of the lower frequency of these severe forms of mountain sickness. "
01/01/2004 - "The study objective was to determine whether acetazolamide is effective in prophylaxis of acute mountain sickness (AMS) at moderate altitude in ambulatory travelers not undergoing vigorous exercise. "
09/01/2012 - "Acetazolamide has been reported to be effective in the prevention of acute mountain sickness (AMS). "
01/01/2012 - "Acetazolamide at doses of 250 mg, 500 mg, and 750 mg were all effective in preventing acute mountain sickness above 3000 m, with a combined odds ratio of 0.36 (95% confidence interval 0.28 to 0.46). "

05/13/1995 - "After one hour of treatment compression with 193 mbar caused a significantly greater relief of symptoms of acute mountain sickness than dexamethasone (Lake Louise score: mean (SD) -4.6 (1.9) v -2.5 (1.8); clinical score: -4.0 (1.2) v -1.5 (1.4); AMS-C score: -1.24 (0.51) v -0.54 (0.59)). "
03/01/1991 - "Compared with placebo, dexamethasone appears to be effective for prophylaxis of symptoms associated with acute mountain sickness accompanying rapid ascent. "
05/13/1995 - "Evaluation and comparison of the therapeutic efficacy of a portable hyperbaric chamber and dexamethasone in the treatment of acute mountain sickness. "
12/21/1989 - "However, the efficacy of dexamethasone in the treatment of established acute mountain sickness remains uncertain. "
05/13/1995 - "Simulated descent v dexamethasone in treatment of acute mountain sickness: a randomised trial."

10/01/1991 - "Simulated descent in a fabric hyperbaric chamber is as effective as oxygen therapy for the immediate relief of acute mountain sickness."
09/01/2014 - "The study evaluated the predictive value of arterial oxygen saturation (SaO2) after 30-min hypoxic exposure on subsequent development of acute mountain sickness (AMS) and tested if additional resting cardio-respiratory measurements improve AMS prognosis. "
06/01/2012 - "The purpose of this trial was to establish whether changes in resting oxygen saturation (Spo(2)) during ascent of Jade Mountain is useful in predicting acute mountain sickness (AMS). "
06/01/2012 - "The purpose of this study was to determine whether arterial oxygen saturation (Spo(2)) and heart rate (HR), as measured by a finger pulse oximeter on rapid arrival to 4260 m, could be predictive of acute mountain sickness (AMS) or summit success on a climb to 5640 m. "
07/05/2007 - "We conducted a prospective, single-blind, controlled hypobaric-chamber study of adult volunteers to determine the effect of barometric pressures equivalent to terrestrial altitudes of 650, 4000, 6000, 7000, and 8000 ft (198, 1219, 1829, 2134, and 2438 m, respectively) above sea level on arterial oxygen saturation and the occurrence of acute mountain sickness and discomfort as measured by responses to the Environmental Symptoms Questionnaire IV during a 20-hour simulated flight. "

06/01/2012 - "Compared with placebo, ibuprofen was effective in reducing the incidence of acute mountain sickness."
06/01/2013 - "In reply to "ibuprofen for prevention of acute mountain sickness-is bigger really better?"."
06/01/2013 - "Ibuprofen for prevention of acute mountain sickness: is bigger really better?"
01/23/2013 - "Ibuprofen can prevent acute mountain sickness."
12/01/2012 - "Does ibuprofen prevent acute mountain sickness?"

01/01/2014 - "Efficacy of NSAIDs for the prevention of acute mountain sickness: a systematic review and meta-analysis."
12/01/2012 - "Altitude Sickness in Climbers and Efficacy of NSAIDs Trial (ASCENT): randomized, controlled trial of ibuprofen versus placebo for prevention of altitude illness."

03/01/2011 - "Over the last 20 years a number of small trials have reported that spironolactone effectively prevents acute mountain sickness (AMS), but to date there have been no large randomized trials investigating the efficacy of spironolactone in prevention of AMS. "
06/01/1986 - "This study examined the effectiveness of spironolactone as a prophylactic agent for the prevention of acute mountain sickness (AMS). "
06/01/1986 - "Effect of spironolactone on acute mountain sickness."
12/06/1980 - "Spironolactone prophylaxis of mountain sickness."
08/30/1980 - "Spironolactone prophylaxis in mountain sickness."

01/01/2000 - "A randomized two-part study was conducted in order to determine the efficacy of theophylline in the treatment of acute mountain sickness during fast ascent to altitudes >2,500 m. "
09/01/2008 - "Low-dose theophylline reduces symptoms of acute mountain sickness."
05/01/2001 - "Does theophylline really improve acute mountain sickness?"
03/01/2001 - "Does theophylline really improve acute mountain sickness?"
01/01/2000 - "In conclusion, oral slow-release theophylline improves acute mountain sickness."

05/01/2010 - "To study on the protective effects of new compound codonopsis tablets against acute mountain sickness (AMS). "
05/01/2010 - "[Protective effects of new compound codonopsis tablets against acute mountain sickness]."
05/01/2010 - "New compound codonopsis tablets have an obvious effect on prevention and treatment of acute mountain sickness."

01/01/2015 - "Investigation of the Hepato-Protective Effects of Imdur in a Rat Model of Chronic Mountain Sickness."
01/01/2015 - "The objective of this study was to determine if the clinical nitrate, Imdur, has a hepato-protective effect in chronic mountain sickness (CMS). "

03/01/2015 - "By contrast, volunteers with acute mountain sickness (AMS) exhibited a marked decrease in HOMA insulin sensitivity (HOMA-IS) and enhanced plasma CRH. "
09/01/2013 - "Reduced insulin sensitivity might increase the susceptibility to acute mountain sickness (AMS). "
09/01/2013 - "Reduced insulin sensitivity as a marker for acute mountain sickness?"
06/01/2015 - "Individuals with type 1 diabetes traveling to altitude and their physicians should be vigilant for this complication and should be aware of the effects of conventional first-line therapies for acute mountain sickness on insulin requirement, glycemic control, and preexisting microvascular diabetes complications. "
03/01/2011 - "We investigated insulin requirements, energy expenditure, and glucose levels at very high altitude in relation to acute mountain sickness (AMS) symptoms in individuals with type 1 diabetes. "

01/01/2011 - "Research has investigated the efficacy of intravenous hyperoxygenated solutions (HOS) as auxiliary oxygen supplies in several hypoxic states including cardiopulmonary resuscitation, respiratory failure, cerebrovascular disease, myocardial ischaemia, severe acute respiratory syndrome, poisoning, neonatal hypoxia, altitude sickness, large burns and traumatic haemorrhagic shock. "

08/01/2004 - "This field study shows that PEEP could be an efficient method with which to prevent acute mountain sickness without adverse effects. "
08/01/2004 - "This study evaluates the ability of positive end-expiratory pressure (PEEP), a nonpharmacological method, to prevent the occurrence of acute mountain sickness during two ascents of Mount Blanc. "
02/01/2010 - "Non-invasive positive pressure ventilation during sleep at 3800 m: Relationship to acute mountain sickness and sleeping oxyhaemoglobin saturation."
08/01/2004 - "The decrease in the prevalence of acute mountain sickness indicated that the PEEP system was effective, one case (12.5%) occurring among the eight participants with PEEP and six cases (75%) occurring among the eight without PEEP (P<0.01). "
08/01/2004 - "Prevention of acute mountain sickness by low positive end-expiratory pressure in field conditions."

05/01/1999 - "Acute mountain sickness is not related to cerebral blood flow: a decompression chamber study."
05/01/1999 - "To evaluate the pathogenetic role of cerebral blood flow (CBF) changes occurring before and during the development of acute mountain sickness (AMS), peak mean middle cerebral artery flow velocities () were assessed by transcranial Doppler sonography in 10 subjects at 490-m altitude, and during three 12-min periods immediately (SA1), 3 (SA2), and 6 (SA3) h after decompression to a simulated altitude of 4,559 m. "
05/15/1986 - "Potential usefulness of these compounds in the prevention of decompression syndrome (DCS) and acute mountain sickness (AMS) are discussed."
03/25/2003 - "The author examines Glaisher's account of balloon sickness by comparing it with other balloonists' observations and discussing it in the context of altitude sickness, decompression injury, and hypoxemia."
03/25/2003 - "James Glaisher's 1862 account of balloon sickness: altitude, decompression injury, and hypoxemia."

03/01/2014 - "This study was performed to evaluate whether increasing hemoglobin before ascent by prophylactic erythropoietin injections prevents acute mountain sickness (AMS). "

09/01/2015 - "Their personal use of medications and home remedies and presence of acute mountain sickness (AMS) symptoms were also assessed. "
02/01/2012 - "The combination of the 3 plants may well support their use in traditional medicine to combat oxidative stress and high-altitude sickness."
04/27/2012 - "Rhodiola rosea is a commonly used folk medicine for the treatment of high altitude sickness, mountain malhypoxia, and anoxia. "
01/27/2011 - "Rhodiola rosea is commonly used in China and Tibet folk medicine for the treatment of high altitude sickness, anoxia and mountain malhypoxia. "