HOME PRODUCTS SERVICES COMPANY CONTACT FAQ

Alprenolol

One of the ADRENERGIC BETA-ANTAGONISTS used as an antihypertensive, anti-anginal, and anti-arrhythmic agent.

Also Known As:

1-(o-Allylphenoxy)-3-(isopropylamino)-2-propanol; Alfeprol; Alpheprol; Alprenolol Hydrochloride; Aptin; Aptin-Duriles; Aptina; Aptine; Astra Brand of Alprenolol Benzoate; Astra Brand of Alprenolol Hydrochloride; H-56-28; Made Brand of Alprenolol Hydrochloride; Aptin Duriles; AptinDuriles; H 56 28; H5628; 2-Propanol, 1-((1-methylethyl)amino)-3-(2-(2-propenyl)phenoxy)-

Networked: 144 relevant articles (4 outcomes, 9 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 58
- Amines: 1422
  - Amino Alcohols: 14
    - Propanolamines: 3
      - Phenoxypropanolamines: 1
        Alprenolol: 144
        Dihydroalprenolol: 40
        bromoacetylalprenololmenthane: 9
        1-(2-allylphenoxy)-3-((1-amino-4-menthane-8-yl)amino)-2-propanol
        1-(2-allylphenoxy)-3-((1-bromoacetylamino-4-menthane-8-yl)amino)-2-propanol
        1-(2-allylphenoxy)-3-((8-amino-4-menthane-1-yl)amino)-2-propanol
        1-(2-allylphenoxy)-3-((8-bromoacetylamino-4-menthane-1-yl)amino)-1-propanol
        4-hydroxyalprenolol
        4-hydroxyalprenolol glucuronide
        4-hydroxyphenethylamino-3-(2-allyl)phenoxypropan-2-ol
        alprenolol glucuronide
        alprenolol-NBD
        alprenolone methoxime
        alprenoxime
        dansyl alprenolol
        pargolol
- Alcohols: 387
  - Amino Alcohols: 14
    - Propanolamines: 3
      - Alprenolol: 144
        Dihydroalprenolol: 40
        bromoacetylalprenololmenthane: 9
        1-(2-allylphenoxy)-3-((1-amino-4-menthane-8-yl)amino)-2-propanol
        1-(2-allylphenoxy)-3-((1-bromoacetylamino-4-menthane-8-yl)amino)-2-propanol
        1-(2-allylphenoxy)-3-((8-amino-4-menthane-1-yl)amino)-2-propanol
        1-(2-allylphenoxy)-3-((8-bromoacetylamino-4-menthane-1-yl)amino)-1-propanol
        4-hydroxyalprenolol
        4-hydroxyalprenolol glucuronide
        4-hydroxyphenethylamino-3-(2-allyl)phenoxypropan-2-ol
        alprenolol glucuronide
        alprenolol-NBD
        alprenolone methoxime
        alprenoxime
        dansyl alprenolol
        pargolol
  - Propanols: 2
    - Propanolamines: 3
      - Alprenolol: 144
        Dihydroalprenolol: 40
        bromoacetylalprenololmenthane: 9
        1-(2-allylphenoxy)-3-((1-amino-4-menthane-8-yl)amino)-2-propanol
        1-(2-allylphenoxy)-3-((1-bromoacetylamino-4-menthane-8-yl)amino)-2-propanol
        1-(2-allylphenoxy)-3-((8-amino-4-menthane-1-yl)amino)-2-propanol
        1-(2-allylphenoxy)-3-((8-bromoacetylamino-4-menthane-1-yl)amino)-1-propanol
        4-hydroxyalprenolol
        4-hydroxyalprenolol glucuronide
        4-hydroxyphenethylamino-3-(2-allyl)phenoxypropan-2-ol
        alprenolol glucuronide
        alprenolol-NBD
        alprenolone methoxime
        alprenoxime
        dansyl alprenolol
        pargolol

Experts

1.	Joshi, R: 1 article (10/2015)
2.	Valdez, D J: 1 article (10/2015)
3.	Bouvier, M: 1 article (10/2015)
4.	Bond, R A: 1 article (10/2015)
5.	Thanawala, V J: 1 article (10/2015)
6.	Parra, S: 1 article (10/2015)
7.	Leff, P: 1 article (10/2015)
8.	Knoll, B J: 1 article (10/2015)
9.	Forkuo, G S: 1 article (10/2015)
10.	Taira, Carlos A: 1 article (01/2010)

Related Diseases

1.	Myocardial Infarction 12/18/1978 - "An improvement in the prognosis of myocardial infarction has been reported after long term treatment with alprenolol 200 mg twice daily. " 07/01/1983 - "Study patients received alprenolol 200 mg twice daily for 12-41 months (mean: 24 months) as a secondary preventive measure following a myocardial infarction. " 03/01/1970 - "Alprenolol in acute myocardial infarction: Double-blind trial." 01/01/1984 - "The data suggest that alprenolol can be given in the acute phase of myocardial infarction without causing any additional disturbance in the serum levels of T3 and T4." 01/01/1984 - "Serum levels of T4, T3 rT3 and resin T3 uptake were followed for 5 days in 40 patients with acute myocardial infarction (AMI) allocated to early treatment either with alprenolol or placebo. "
2.	Sudden Death 06/18/1975 - "[Reduction of sudden death after myocardial infarct with chronic alprenolol treatment]." 01/16/1982 - "The significant reduction in sudden death was comparable with that after alprenolol, practolol, and timolol, which suggests that the mechanism of prevention is beta-blockade rather than any other pharmacological property of the individual drugs." 01/01/1981 - "The studies presented support the concept that practolol and alprenolol reduce the long-term mortality due to sudden death from ischemic heart disease after myocardial infarction. "
3.	Tachycardia (Tachyarrhythmias) 04/01/1979 - "The plasma concentrations of alprenolol and its metabolite 4-hydroxy-alprenolol and the inhibition of exercise tachycardia were studied for 7 hr after the alprenolol. " 12/01/1977 - "Furthermore, we suggest that in conscious dogs the tachycardia produced by the systemic administration of dl-alprenolol is not entirely due to its intrinsic sympathomimetic effect." 10/01/1976 - "4. Alprenolol attentuated the exercise tachycardia during both types of exercise. " 01/01/1984 - "Prophylactic effect of alprenolol on ventricular tachyarrhythmias during the in-patient phase of acute myocardial infarction." 12/18/1978 - "The reduction in exercise-induced tachycardia as a measure of cariac beta-adrenoceptor blockade was significantly greater after pindolol 15 mg and 20 mg than after alprenolol 200 mg. On the morning of the fourth day, i.e. "
4.	Cardiac Arrhythmias (Arrythmia) 07/01/1976 - "[Treatment of cardiac arrhythmias by alprenolol (1-(2-allyphenoxy) 3 isopropyl aminopropanol)]." 07/11/1972 - "Use of alprenolol in acute cardiac arrhythmias." 07/01/1972 - "[Value of alprenolol in the prevention of paroxysmal cardiac arrhythmias]." 01/01/1972 - "Alprenolol as maintenance therapy for the protection against arrhythmia relapse in patients with DC-converted chronic atrial fibrillation." 05/01/1967 - "A new beta-adrenergic receptor blocking agent, H 56/28, in the treatment of cardiac arrhythmias."
5.	Atrial Fibrillation 01/01/1972 - "Alprenolol as maintenance therapy for the protection against arrhythmia relapse in patients with DC-converted chronic atrial fibrillation." 10/01/1970 - "[Alprenolol-quinidine combination in the treatment of chronic atrial fibrillation]." 04/01/1977 - "Experiments have demonstrated that Alfeprol arrests atrial fibrillation in dogs induced by electric stimulation of the heart, and atrial fibrillation in cats modelled by Akonitine application; it suppresses ventricular tachycardia in dogs occurring following an occlusion of the branches of coronary arteries, and in cats when induced by strophantin intoxication; it prevents fatal ventricular fibrillation in rats poisoned by calcium chloride. "

Related Drugs and Biologics

1.	Pindolol (LB 46)
2.	Practolol
3.	Oxprenolol (Trasicor)
4.	Acebutolol (Prent)
5.	Timolol (Blocadren)
6.	Propranolol (Inderal)
7.	Alprenolol
8.	Metoprolol (Lopressor)
9.	Atenolol (Tenormin)
10.	Epinephrine (Adrenaline)

Related Therapies and Procedures

1.	Aftercare (After-Treatment)
2.	Intravenous Injections
3.	Anesthesia