Allylisopropylacetamide

05/01/1986 - "Porphyria was induced in adult male Wistar rats starved for 24 hr by SC injection of 400 mg/kg allylisopropylacetamide (AIA). "
07/01/1987 - "The effects of haem arginate and haematin upon the allylisopropylacetamide induced experimental porphyria in rats."
12/15/1983 - "In rhesus monkeys, in which porphyria was induced by the administration of allylisopropylacetamide (AIA), hepatic delta-aminolevulinic acid synthase (ALA-S) was increased. "
07/12/1969 - "Prevention of allylisopropylacetamide induced experimental porphyria in the rat by vitamin E."
01/08/1971 - "Chemically induced porphyria: increased microsomal heme turnover after treatment with allylisopropylacetamide."

07/01/1987 - "Biochemical disorders caused by allylisopropylacetamide in various animal species resemble human acute intermittent porphyria. "
04/14/1995 - "The activity of some heme enzymes and rhodanese in streptozotocin (STZ) induced diabetic mice and in allylisopropylacetamide (AIA) induced experimental acute porphyria mice has been examined. "

05/01/1970 - "Hepatocellular changes associated with allylisopropylacetamide-induced hepatic porphyria in rats."
07/16/1985 - "Heme administration causes inhibition of delta-aminolevulinate synthase (ALAS), best tested in the allylisopropylacetamide (AIA)-treated rat, a model for hepatic porphyrias. "

10/15/1981 - "The induction of ALA synthase in chronic iron overload was enhanced by phenobarbital and allylisopropylacetamide, in spite of the fact that these agents did not increase haem oxygenase activity. "

01/01/1985 - "In the group living under low atmospheric pressure (51 kPa) the enzymic activity, either basal or induced by starvation and/or allylisopropylacetamide, was significantly (p less than 0.001) lower than that of the control group. "