Aldosterone Antagonists

01/01/2011 - "There were marked deficiencies in the prescription of aldosterone antagonists (35%) for severe heart failure, which improved to 44.2% after the intervention. "
01/01/2007 - "Aldosterone antagonists have been proven to be beneficial in severe heart failure (HF) as a result of systolic dysfunction. "
01/01/2013 - "Aldosterone antagonists have previously been shown to improve survival in a wide spectrum of patients with heart failure with reduced ejection fraction (HFrEF), and more recently, small trials suggested that they might have role in HFpEF patients. "
01/01/2014 - "[Are aldosterone antagonists effective in patients with mild to moderate heart failure?]."
09/01/2014 - "Aldosterone antagonists may be helpful in preventing hospitalizations for heart failure exacerbation in CKD patients through a PTH-mediated effect."

04/01/2013 - "Among individuals with resistant hypertension, aldosterone antagonists have also been shown to be effective in lowering blood pressure. "
12/01/2009 - "This suggests that aldosterone antagonists may be useful for the treatment of hypertension among AAs, regardless of BMI."
11/01/2015 - "A few studies have shown aldosterone antagonists (AA) to be effective therapy in patients with resistant hypertension (RH). "
11/01/2015 - "The Effects of Aldosterone Antagonists in Patients With Resistant Hypertension: A Meta-Analysis of Randomized and Nonrandomized Studies."
01/01/2012 - "Recent clinical studies indicate that the administration of aldosterone antagonists as a fourth therapeutic line provides significant additional blood pressure reduction, when added to previous antihypertensive regimens in subjects with resistant hypertension."

03/01/2006 - "Recent data indicate that aldosterone antagonists may be effective when added to existing antihypertensive regimens even in the absence of primary aldosteronism."
01/15/2006 - "These observations are in contrast with the results of international studies which showed a high frequency of normokalemic primary aldosteronism and a more frequent occurrence of idiopathic hyperaldosteronism well treatable with aldosterone-antagonists. "
01/01/1981 - "We conclude that aldosterone antagonists in the dosage used had no effect on the course of postoperative hyperaldosteronism."
10/01/2013 - "Response to Effectiveness of adrenalectomy and aldosterone antagonists for long-term treatment of primary aldosteronism."
10/01/2013 - "Effectiveness of adrenalectomy and aldosterone antagonists for long-term treatment of primary aldosteronism."

01/01/2014 - "Gap between clinical guidelines and practice: the case of aldosterone-antagonists in patients with myocardial infarction."
10/01/2013 - "Use of aldosterone antagonists at discharge after myocardial infarction: results from the National Cardiovascular Data Registry Acute Coronary Treatment and Intervention Outcomes Network (ACTION) Registry-Get with the Guidelines (GWTG)."
01/08/2013 - "Temporal trends and predictors in the use of aldosterone antagonists post-acute myocardial infarction."
11/01/2011 - "The use of aldosterone antagonists in post-acute myocardial infarction is only 54.8% of the optimal candidates. "
11/01/2011 - "From a total of 2703 patients with acute myocardial infarction, 416 (15.4%) were considered optimal candidates to receive aldosterone antagonists, but only 228 (54.8%) received the treatment. "

02/01/2007 - "These findings suggested that MRs were upregulated in atrial fibrillation and aldosterone antagonists may be effective in treating atrial fibrillation."
06/01/2014 - "The study reveals poor adherence to current therapeutic guidelines for CHF, particularly with regard to aldosterone antagonists and anticoagulant therapy in the presence of atrial fibrillation. "
01/01/2015 - "Overall, Asian-American HF patients had comparable quality of care except that they were less likely to receive aldosterone antagonists at discharge (relative risk <RR>, 0.88; 95% confidence interval <CI>, 0.78-0.99), and anticoagulation for atrial fibrillation (RR, 0.91; 95% CI, 0.85-0.97) even after risk adjustment. "
04/30/2013 - "Aldosterone antagonists, did not appear to play a role in the prevention of new onset atrial fibrillation (RR=0.77, 95%CI: 0.55-1.08, p-value: 0.21). "
01/01/2012 - "Antiarrhythmic potential of aldosterone antagonists in atrial fibrillation."