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Alcuronium (Alcuronium Chloride)
A non-depolarizing skeletal muscle relaxant similar to TUBOCURARINE. It is used as an anesthesia adjuvant.
Also Known As:
Alcuronium Chloride
; Alcuronium Dichloride; Alloferin; Dialferine; N,N'-Diallylnortoxiferinium Dichloride; Dichloride, Alcuronium; Dichloride, N,N'-Diallylnortoxiferinium; Allnortoxiferine; Diallylnortoxiferine; Toxiferine I, 4,4'-didemethyl-4,4'-di-2-propenyl-
Networked:
55
relevant articles (
2
outcomes,
3
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Organic Chemicals: 133
Amines: 4871
Quaternary Ammonium Compounds: 136
Toxiferine: 5
Alcuronium: 55
Onium Compounds
Quaternary Ammonium Compounds: 136
Toxiferine: 5
Alcuronium: 55
Heterocyclic Compounds: 198
Alkaloids: 5398
Benzylisoquinolines: 151
Toxiferine: 5
Alcuronium: 55
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Isoquinolines: 34
Benzylisoquinolines: 151
Toxiferine: 5
Alcuronium: 55
Tetrahydroisoquinolines: 44
Toxiferine: 5
Alcuronium: 55
Experts
1.
Katerere, D
: 1 article (01/2000)
2.
Parry, O
: 1 article (01/2000)
Related Diseases
1.
Hypoventilation
08/01/1992 - "
The risk of intraoperative hypoventilation and hypoxemia was eliminated, yet, due to the lack of adequate monitoring techniques the slow recovery from curare, alcuronium or pancuronium neuromuscular blockade was hardly appreciated.(ABSTRACT TRUNCATED AT 400 WORDS)
"
2.
Congenital Heart Defects (Congenital Heart Defect)
04/01/1993 - "
Delayed onset of alcuronium effect in children with cyanotic congenital heart disease.
"
04/01/1993 - "
These results confirm that the clinical onset of relaxation is delayed in children with cyanotic congenital heart disease, possibly because of delayed distribution of alcuronium.
"
04/01/1993 - "
The effect of alcuronium dichloride (0.3 mg/kg) was studied in seven normal children (Group A), nine with acyanotic congenital heart disease (Group B) and eight with cyanotic disease (Group C).
"
3.
Hypoxia (Hypoxemia)
08/01/1992 - "
The risk of intraoperative hypoventilation and hypoxemia was eliminated, yet, due to the lack of adequate monitoring techniques the slow recovery from curare, alcuronium or pancuronium neuromuscular blockade was hardly appreciated.(ABSTRACT TRUNCATED AT 400 WORDS)
"
4.
Hypersensitivity (Allergy)
05/01/1980 - "
One patient had systemic hypersensitivity and positive intradermal tests to d-tubocurarine and alcuronium.
"
05/01/1980 - "
The second had systemic hypersensitivity to d-tubocurarine and positive intradermal tests to d-tubocurarine, alcuronium, and pancuronium.
"
03/01/1985 - "
However, not much is known about histamine release due to some drugs such as trimethaphan and muscle relaxants other than d-tubocurarine, like alcuronium, pancuronium or succinylcholine, although many clinical reports related to hypersensitivity reactions due to muscle relaxants can be found.
"
01/01/1994 - "
Not only was suxamethonium the most frequently reported drug, but in this study 11 reactions were identified as Type 1 response: no allergic reactions were identified for either vecuronium or atracurium, although single cases were identified for alcuronium, gallamine, and tubocurarine, with two unidentified.
"
5.
Myasthenia Gravis
03/01/1994 - "
This study observed the effects of alcuronium treatment in myasthenia gravis patients as compared with non-MG patients during operation.
"
03/01/1994 - "
Myasthenia gravis patients are hypersensitive to nondepolarizing relaxants, such as alcuronium, an intermediate-long nondepolarizing agent.
"
09/01/1985 - "
We report a case of alcuronium induced postoperative apnoea due to latent myasthenia gravis in a patient with no other clinical manifestations of the disease at presentation.
"
Related Drugs and Biologics
1.
Pancuronium (Pavulon)
2.
Curare
3.
Tubocurarine (Tubocurarine Chloride)
4.
Succinylcholine (Suxamethonium Chloride)
5.
Gallamine Triethiodide (Gallamine)
6.
Vecuronium Bromide (Vecuronium)
7.
Atracurium (Tracrium)
8.
Nitrous Oxide (Laughing Gas)
9.
Fentanyl (Sublimaze)
10.
Thiopental (Pentothal)
Related Therapies and Procedures
1.
Cardiopulmonary Bypass (Heart-Lung Bypass)
2.
Anesthesia
3.
Hip Replacement Arthroplasty (Total Hip Replacement)
4.
Kidney Transplantation
5.
Tourniquets