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Alcohol Amnestic Disorder

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A mental disorder associated with chronic ethanol abuse (ALCOHOLISM) and nutritional deficiencies characterized by short term memory loss, confabulations, and disturbances of attention. (Adams et al., Principles of Neurology, 6th ed, p1139)

Also Known As:

Alcohol Amnestic Syndrome; Alcohol-Induced Amnestic Psychosis; Alcohol-Induced Dysmnesic Psychosis; Alcohol-Induced Dysmnesic Syndrome; Alcohol-Induced Korsakoff Syndrome; Alcohol-Induced Persisting Amnestic Disorder; Alcohol Amnestic Disorders; Alcohol Amnestic Syndromes; Alcohol Induced Amnestic Psychosis; Alcohol Induced Amnestic Syndrome; Alcohol Induced Dysmnesic Psychosis; Alcohol Induced Dysmnesic Syndrome; Alcohol Induced Korsakoff Syndrome; Alcohol Induced Persisting Amnestic Disorder; Alcohol-Induced Amnestic Psychoses; Alcohol-Induced Amnestic Syndromes; Alcohol-Induced Dysmnesic Psychoses; Alcohol-Induced Dysmnesic Syndromes; Alcohol-Induced Korsakoff Syndromes; Alcoholic Korsakoff Syndromes; Amnestic Disorder, Alcohol; Amnestic Disorders, Alcohol; Amnestic Psychoses, Alcohol-Induced; Amnestic Psychosis, Alcohol Induced; Amnestic Syndrome, Alcohol; Amnestic Syndrome, Alcohol-Induced; Amnestic Syndromes, Alcohol; Amnestic Syndromes, Alcohol-Induced; Dysmnesic Psychoses, Alcohol-Induced; Dysmnesic Psychosis, Alcohol-Induced; Dysmnesic Syndrome, Alcohol-Induced; Dysmnesic Syndromes, Alcohol-Induced; Korsakoff Syndrome, Alcohol-Induced; Korsakoff Syndrome, Alcoholic; Korsakoff Syndromes, Alcohol-Induced; Korsakoff Syndromes, Alcoholic; Psychoses, Alcohol-Induced Amnestic; Psychoses, Alcohol-Induced Dysmnesic; Psychosis, Alcohol-Induced Amnestic; Psychosis, Alcohol-Induced Dysmnesic; Syndrome, Alcohol Amnestic; Syndrome, Alcohol-Induced Amnestic; Syndrome, Alcohol-Induced Dysmnesic; Syndrome, Alcohol-Induced Korsakoff; Syndrome, Alcoholic Korsakoff; Syndromes, Alcohol Amnestic; Syndromes, Alcohol-Induced Amnestic; Syndromes, Alcohol-Induced Dysmnesic; Syndromes, Alcohol-Induced Korsakoff; Syndromes, Alcoholic Korsakoff; Alcohol-Induced Amnestic Syndrome; Alcoholic Korsakoff Syndrome; Amnestic Psychosis, Alcohol-Induced

Networked: 11 relevant articles (2 outcomes, 1 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Opioid-Related Disorders (Opiate Addiction)
2.	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
3.	Mood Disorders (Mood Disorder)
4.	Panic Disorder (Panic Attack)
5.	Rett Syndrome (Rett's Disorder)

Experts

1.	Tsaluchidu, Sofia: 1 article (01/2008)
2.	Cocchi, Massimo: 1 article (01/2008)
3.	Tonello, Lucio: 1 article (01/2008)
4.	Puri, Basant K: 1 article (01/2008)
5.	Barker, A: 1 article (03/2001)
6.	Angunawela, I I: 1 article (03/2001)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Alcohol Amnestic Disorder:

1.	Fluvoxamine (Luvox)FDA LinkGeneric 01/01/1988 - "Alcohol amnestic syndrome patients who had the highest blood levels of fluvoxamine demonstrated the largest changes in CSF 5HIAA and improvement in memory performance under fluvoxamine. " 09/01/1994 - "Eight patients suffering from the alcoholic Korsakoff syndrome (AKS) were entered in a double-blind cross-over trial of fluvoxamine 200 mg per day for 4 weeks versus matched placebo for 4 weeks. " 09/01/1994 - "Effects of fluvoxamine treatment on cognitive functioning in the alcoholic Korsakoff syndrome." 07/01/1989 - "In a 4-week double-blind crossover design, the serotonin-uptake blocker fluvoxamine maleate (100 to 200 mg/d) was found to improve episodic memory in only the patients with alcohol amnestic disorder. "
2.	Serotonin (5 Hydroxytryptamine)IBA 07/01/1989 - "In a 4-week double-blind crossover design, the serotonin-uptake blocker fluvoxamine maleate (100 to 200 mg/d) was found to improve episodic memory in only the patients with alcohol amnestic disorder. "
3.	Clonidine (ST 155)FDA LinkGeneric 01/01/1984 - "Since this drug is likely to be more widely prescribed to normotensive patients with neuropsychiatric diseases, we studied neurochemical, cardiovascular, and behavioral changes upon placebo substitution in seven patients receiving clonidine (6 micrograms/kg/day for 3 weeks) for treatment of alcohol amnestic disorder. " 01/01/1983 - "Seven normotensive patients with alcohol amnestic disorder were treated with 2 micrograms/kg clonidine (C) three times daily for 1 wk. Four patients received 12 micrograms/kg/day during the subsequent week; three developed hypotensive symptoms at this dose and remained on 6 micrograms/kg/day. " 01/01/1983 - "Urinary catecholamine metabolites and effects of clonidine in patients with alcohol amnestic disorder." 01/01/1987 - "Clonidine has been studied for use in neonatal narcotic addiction, alcohol detoxification, akathisia, mania, narcolepsy, attention deficit disorder, panic disorder, and alcohol amnestic disorder. " 03/01/1984 - "Cerebrospinal fluid (CSF; n = 5) and plasma (n = 7) levels of norepinephrine (NE) and its major metabolite, 3-methoxy-4-hydroxyphenylglycol (MHPG) were examined in abstinent normotensive men with alcohol amnestic disorder during placebo and after 2 wk of clonidine treatment (6 or 12 micrograms/kg/day). "
4.	Paroxetine (Paxil)FDA LinkGeneric 01/01/1999 - "Paroxetine treatment in alcohol amnestic disorder."
5.	Norepinephrine (Noradrenaline)FDA LinkGeneric 03/01/1984 - "Cerebrospinal fluid (CSF; n = 5) and plasma (n = 7) levels of norepinephrine (NE) and its major metabolite, 3-methoxy-4-hydroxyphenylglycol (MHPG) were examined in abstinent normotensive men with alcohol amnestic disorder during placebo and after 2 wk of clonidine treatment (6 or 12 micrograms/kg/day). "
6.	Nicotine FDA Link 01/01/2008 - "There was published evidence of increased oxidative stress in the following DSM-IV-TR diagnostic categories: mental retardation; autistic disorder; Rett's disorder; attention-deficit hyperactivity disorder; delirium; dementia; amnestic disorders; alcohol-related disorders; amphetamine (or amphetamine-like)-related disorders; hallucinogen-related disorders; nicotine-related disorders; opioid-related disorders; schizophrenia and other psychotic disorders; mood disorders; anxiety disorders; sexual dysfunctions; eating disorders; and sleep disorders. "
7.	NeuropeptidesIBA 06/01/1991 - "Pituitary-adrenal responses to oCRH and central neuropeptide levels in alcohol amnestic disorder."
8.	MethoxyhydroxyphenylglycolIBA 03/01/1984 - "Cerebrospinal fluid (CSF; n = 5) and plasma (n = 7) levels of norepinephrine (NE) and its major metabolite, 3-methoxy-4-hydroxyphenylglycol (MHPG) were examined in abstinent normotensive men with alcohol amnestic disorder during placebo and after 2 wk of clonidine treatment (6 or 12 micrograms/kg/day). "
9.	Cholinesterase Inhibitors (Anticholinesterases)IBA 03/01/2001 - "Anticholinesterase drugs for alcoholic Korsakoff syndrome."
10.	Amphetamine (Amfetamine)FDA LinkGeneric 01/01/2008 - "There was published evidence of increased oxidative stress in the following DSM-IV-TR diagnostic categories: mental retardation; autistic disorder; Rett's disorder; attention-deficit hyperactivity disorder; delirium; dementia; amnestic disorders; alcohol-related disorders; amphetamine (or amphetamine-like)-related disorders; hallucinogen-related disorders; nicotine-related disorders; opioid-related disorders; schizophrenia and other psychotic disorders; mood disorders; anxiety disorders; sexual dysfunctions; eating disorders; and sleep disorders. "