AIDS-Related Complex (ARC)

A prodromal phase of infection with the human immunodeficiency virus (HIV). Laboratory criteria separating AIDS-related complex (ARC) from AIDS include elevated or hyperactive B-cell humoral immune responses, compared to depressed or normal antibody reactivity in AIDS; follicular or mixed hyperplasia in ARC lymph nodes, leading to lymphocyte degeneration and depletion more typical of AIDS; evolving succession of histopathological lesions such as localization of Kaposi's sarcoma, signaling the transition to the full-blown AIDS.

Also Known As:

Networked: 7288 relevant articles (237 outcomes, 867 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Acquired Immunodeficiency Syndrome (AIDS)
2.	AIDS-Related Complex (ARC)
3.	HIV Infections (HIV Infection)
4.	Neutropenia
5.	Contracture

Experts

1.	Cozzi, Luca: 24 articles (04/2015 - 07/2003)
2.	Bramham, Clive R: 19 articles (10/2015 - 03/2002)
3.	Fogliata, Antonella: 19 articles (10/2013 - 07/2003)
4.	Yada, Toshihiko: 18 articles (08/2015 - 04/2003)
5.	Worley, Paul F: 18 articles (04/2015 - 12/2002)
6.	Shuttleworth, Trevor J: 18 articles (02/2015 - 03/2003)
7.	Antonini, James M: 17 articles (02/2015 - 04/2003)
8.	Mintz, Gary S: 15 articles (01/2016 - 07/2002)
9.	Thompson, Jill L: 15 articles (02/2015 - 03/2003)
10.	Smith, Jeremy T: 14 articles (01/2015 - 07/2005)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to AIDS-Related Complex:

1.	Zidovudine (Retrovir)FDA LinkGeneric 08/01/1991 - "These data confirm the efficacy of zidovudine therapy after 4 weeks' treatment in the reduction of development of OI in patients with ARC and support the use of a maintenance dose of 250 mg zidovudine 6-hourly. " 08/01/1990 - "We have used the population pharmacokinetics model as implemented by the computer program NONMEM to study the distribution of zidovudine in a large number of patients who have AIDS-related complex and who are therefore at an earlier stage of immunosuppression than subjects in other studies. " 01/01/1991 - "Of those with ARC, 20% (23%) were using zidovudine at visit 7 and 55% (65%) at visit 11. " 11/01/1990 - "Neuropsychological and psychiatric changes following treatment of ARC patients with zidovudine." 08/01/1990 - "The three other patients with ARC developed muscle pains or weakness and elevated serum CK while on zidovudine. "
2.	XenonIBA 11/01/2005 - "Performance validation of an improved Xenon-arc lamp-based CCD camera system for multispectral imaging in proteomics." 01/01/2005 - "Effect of the increase of energy density on Knoop hardness of dental composites light-cured by conventional QTH, LED and xenon plasma arc." 12/01/2002 - "Xenon plasma arc lights were introduced recently for light-cured orthodontic bonding. " 01/01/2001 - "The remaining 6 groups (3 for each adhesive) were cured with the xenon arc light for 2, 5, and 10 seconds. " 04/01/2013 - "The purpose of these clinical trials was to determine if 300 W and 150 W xenon arc solar simulators (SSs) deliver the same sun protection factor (SPF) and UVA protection factor (PFA). "
3.	TungstenIBA 03/01/2009 - "The purpose of this study was to determine colour changes in a composite cured with tungsten-halogen, light-emitting diode (LED) or a plasma arc after 5 years. " 03/01/2009 - "The corresponding specimens were cured with a tungsten-halogen curing light, a LED unit or with a plasma arc. " 07/01/2009 - "The aim of this study was to evaluate the characteristics of new-generation light-emitting diode (LED) units in comparison with the conventional tungsten-halogen, plasma arc, and first-generation LED units reported in our previous study. " 12/01/2008 - "Fumes generated using three different welding techniques, manual metal arc (MMA) welding, metal inert gas (MIG) welding, and tungsten inert gas (TIG) welding were investigated in the present study. " 05/01/2004 - "This study evaluated the characteristics of two kinds of recently developed light-curing unit; plasma arc and blue light emitting diodes (LED), in comparison with a conventional tungsten-halogen light-curing unit. "
4.	Rely-XIBA 09/01/2014 - "Fiber posts were cemented with a dual-cured cement (Rely X ARC - 3M ESPE). " 04/01/2015 - "Sixty upper premolars were randomly divided into five groups (n=12): 1 - sound teeth; 2 - cavity; 3 - Rely X ARC; 4 - RelyX Unicem; 5 - SeT. " 01/01/2015 - "Posts were luted (Rely X-Arc, 3M ESPE, USA) and composite resin filling cores were prepared for the fracture resistance test (n = 10). " 01/01/2015 - "Rely X ARC showed highest mean bond strength to both the substrates. " 10/01/2014 - "Conversely, Rely X U200 (G3) and Rely X ARC (G4), which presented low solubility and no alteration in pH, caused only slight cytotoxicity to the cultured cells."
5.	Resin Cements (Cement, Resin)IBA 10/01/2011 - "For both resin cements, the best result was produced by the MDP-based primer: ARC 15.9 ± 5.0 MPa and UCem 36.2 ± 2.1 MPa. " 10/01/2011 - "The ceramic plates treated with each of the four methods were further divided into 2 subgroups according to the resin cement tested: RelyXTM ARC (ARC, conventional) and RelyXTM Unicem (Ucem, self-adhesive). " 01/01/2011 - "Four resin cements (A group: Panavia(TM) F; B group: RelyX(TM) ARC; C group: RelyX(TM) Unicem; D group: Clearfil(TM) SA Cement) were applied to the surface of these enamel and dentin discs according to manufacturers' guidance. " 03/01/2004 - "The resin cement was polymerized between a ceramic specimen (diameter 5 mm, height 2 mm) and a dentin disk (diameter 5 mm, height 1 mm) with a conventional halogen light, a high-intensity halogen light, a plasma-arc light, and a light-emitting diode unit. " 02/01/2004 - "A conventional halogen light (Hilux 350, Express Dental Products) and a plasma arc light (Power PAC, ADT) were used to polymerize resin cement. "
6.	Messenger RNA (mRNA)IBA 12/01/2008 - "Our results showed that there was a significant reduction in the percentage of neurons expressing Arc protein 1 week after irradiation, whereas 2 months after irradiation, there was a reduction in the percentage of neurons expressing both Arc mRNA and Arc protein. " 01/01/2015 - "In the present study, we confirmed that Arc messenger RNA was significantly decreased in the DS, but importantly, we identified that this reduction was restricted to the dorsomedial (DMS) and not dorsolateral striatum (DLS). " 01/01/2014 - "These results of studies of mRNA trafficking in neurons in vivo provide a new perspective on the possible roles of Arc in activity-dependent synaptic modifications. " 01/01/2014 - "Findings from in vivo studies that donot quite fit include: (1) Following induction of LTP in vivo, Arc mRNA and protein localize near active synapses, but are also distributed throughout dendrites. " 12/01/2012 - "In this study, Arc expression induced by exposure to a novel environment was used to assess transcriptional activation and cytoplasmic localization of Arc mRNA in striatal efferent neuron subpopulations subsequent to METH-induced neurotoxicity. "
7.	QuartzIBA 12/01/2004 - "An in vivo study to compare a plasma arc light and a conventional quartz halogen curing light in orthodontic bonding." 05/01/2010 - "The spectroscopic method of optical emission was employed to diagnose the characteristic parameters of the arc plasma discharge in the quartz capillary. " 09/01/2006 - "The Glória quartz-monzodiorite shows metaluminous and calc-alkaline tendency with intermediate K content, comparable to that of volcanic-arc rocks. " 09/01/2006 - "The Glória quartz-monzodiorite: isotopic and chemical evidence of arc-related magmatism in the central part of the Paleoproterozoic Mineiro belt, Minas Gerais State, Brazil." 03/01/2008 - "Under our conditions, process dynamics using the W-MDEL light source are greater than with the more conventional photochemical methods that employ low-pressure Hg arc electrode lamps in synthetic quartz to degrade these two toxic contaminants."
8.	ArgonIBA 04/20/2013 - "In experiment, the probe wavelength and the export pressure of argon gas and argon arc plasma are the same. " 04/20/2013 - "The equivalent particle number density distributions of the argon gas and argon arc plasma are reconstructed from the experimentally measured refractive index distributions obtained by moiré tomography, while five cross sections, which are 7, 8.5, 10, 11.5, and 13 mm away from the jet nozzle are chosen for practical calculation and comparison. " 04/20/2013 - "For the purpose of facilitating comparison, argon gas and argon arc plasma are chosen as practical examples for experiment. " 01/01/2013 - "Mn and Pb were determined with a spectrochemical method that has an argon-stabilized U-shaped DC arc with aerosol supply as excitation source. " 12/01/2012 - "All samples were synthesized by arc-melting high purity elements under argon atmosphere. "
9.	Brain-Derived Neurotrophic Factor (BDNF)IBA 07/01/2014 - "All experimental groups showed a significant reduction of BDNF and Arc protein expression in the hippocampus. " 09/12/2011 - "Down-regulation of hippocampal BDNF and Arc associated with improvement in aversive spatial memory performance in socially isolated rats." 01/01/2011 - "Recall during probe trials enhanced Arc expression across multiple cortical regions involved in the cognitive component of water maze learning, while BDNF expression was more homogeneously upregulated across cortical regions involved in the associational and sensorimotor aspects of water maze training. " 08/01/2009 - "Moreover, this study also provides the first evidence that there is a close correlation between BDNF-induced eEF2 dephosphorylation and BDNF-induced Arc expression. " 08/01/2009 - "Our recent study has demonstrated that treatment of fibrillar Abeta at a nonlethal level was sufficient to impair BDNF-induced Arc expression in cultured rat cortical neurons. "
10.	glucuronyl glucosamine glycan sulfate (Vessel)IBA 08/01/2009 - "These utility tools allow lesion assessment, optimal working-view selection for specific vessel segments, and improved guidance via overlay functionality or follow C-arc. " 03/01/2013 - "The arc of the VH-TCFA exposed to the vessel lumen was significantly greater in culprit lesions than in nonculprit lesions (122.28° ± 58 vs 89.46° ± 52; respectively; P = .007). " 01/01/2010 - "The test on the CT data set showed that the resulting average root-mean-square error of the extracted centerline points of the segmented CT data set compared to the error based on the views from the circular arc was reduced from 2.52 to 1.55 mm. In a first test, the method proved to deliver improved image quality by reducing foreshortening and overlap of vessel segments and may therefore also improve the centerline extraction accuracy of the semi-automatic two view modeling method." 06/01/2001 - "The arc of disease-free vessel wall was larger in ruptured than in control plaques (p < 0.0001). " 01/01/2015 - "The material of study is a pressure vessel steel ASTM A516 grade 70 that is used for gas metal arc welding. "

Therapies and Procedures

1.	Radiotherapy 11/01/2011 - "Volumetric modulated arc therapy (VMAT) is a novel radiation technique, which can achieve highly conformal dose distributions with improved target volume coverage and sparing of normal tissues compared with conventional radiotherapy techniques. " 02/01/2007 - "Planning and treatment of the head phantom was associated with an overall accuracy of 2 mm. Comparison to conventional noncoplanar arc fractionated stereotactic radiotherapy plan demonstrated similar target coverage and improved critical tissue sparing even for a challenging anatomy with multiple lesions in the same plane as the optic apparatus. " 03/01/2012 - "The results indicate that the dosimetric robustness of MLC tracking delivery of an inversely optimized arc radiotherapy plan can be improved by incorporating leaf position constraints in the objective function without otherwise affecting the plan quality. " 02/01/2012 - "To develop and compare a volumetric modulated arc therapy (VMAT) technique with conventional radiotherapy for craniospinal irradiation with respect to improved dose conformity and homogeneity in the planning target volume (PTV) and to reduced dose to organs at risk (OAR). " 11/15/2001 - "Our 20-year experience with electron arc radiotherapy has demonstrated the safety and efficacy of this technique. "
2.	Lasers (Laser) 08/01/2006 - "In this study, three-dimensional surface areas of the lateral tibial condyle of humans, chimpanzees, and gorillas were computed using a Digibot II (Digibotics) laser scanner and the DataSculpt v.4.6 engineering software package to evaluate joint surface contours, and compared to two-dimensional surface area and arc and chord length measurements of the anteroposterior and mediolateral axes. " 03/01/1996 - "A small laser target (0.5 mW, 0.5 degree arc) that rotated with the subject was used for fixation trials. " 11/02/2015 - "Remote electrical arc suppression by laser filamentation." 10/02/2015 - "Although both techniques significantly reduced VHN, plasma arc bleaching resulted in a 22.62% reduction in VHN for enamel micro-hardness, whereas an 11.89% reduction in VHN was observed for laser bleaching; this difference is statistically significant (p<0.001). " 06/15/2015 - "We have measured the picosecond laser damage behavior of multilayer dielectric (MLD) diffraction gratings used in the compression of chirped pulses on the Advanced Radiographic Capability (ARC) kilojoule petawatt laser system at the Lawrence Livermore National Laboratory (LLNL). "
3.	Intensity-Modulated Radiotherapy (Radiotherapy, Intensity Modulated) 07/07/2015 - "Utilizing noncoplanar beam angles in volumetric modulated arc therapy (VMAT) has the potential to combine the benefits of arc therapy, such as short treatment times, with the benefits of noncoplanar intensity modulated radiotherapy (IMRT) plans, such as improved organ sparing. " 02/01/2015 - "To study the feasibility of unified intensity-modulated arc therapy (UIMAT) which combines intensity-modulated radiotherapy (IMRT) and volumetric-modulated arc therapy (VMAT) optimization and delivery to produce superior radiation treatment plans, both in terms of dose distribution and efficiency of beam delivery when compared with either VMAT or IMRT alone. " 02/01/2013 - "We present a study comparing both step-and-shoot intensity modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT) techniques to deliver a concomitant hypofractionated prescription dose to the diseased region and to the involved vertebrae. " 01/01/2013 - "The purpose of this study is to assess the feasibility of VMAT1 for NPC by comparing the dosimetry, delivery efficiency, and accuracy with dual arc VMAT (VMAT2), dynamic MLC intensity-modulated radiotherapy (dIMRT), and step-and-shoot intensity-modulated radiotherapy (ssIMRT). " 01/01/2013 - "The purpose of this study was to compare postprostatectomy planning for volumetric-modulated arc therapy (VMAT) with both single arc (SA) and double arcs (DA) against dynamic sliding window intensity-modulated radiotherapy (IMRT). "
4.	Light Coagulation 06/03/1966 - "Destruction of the fovea by photocoagulation decreased acuity to 9 minutes of arc. " 02/01/1984 - "The final results of a randomised controlled study of xenon-arc photocoagulation for proliferative retinopathy are reported, after all patients have been followed for at least 5 years and some for up to 7 years. " 01/01/1982 - "[Light and scanning electron microscopic studies of acute and chronic xenon arc photocoagulation lesions in the retina of mini-pigs]." 09/10/1977 - "[A study of the ultrastructural alterations of rabbit intravitreal retinal vessels induced by xenon arc photocoagulation (author's transl)]." 03/01/1995 - "This eye was treated with xenon-arc photocoagulation and 60Co irradiation. "
5.	Arthroplasty 02/01/2012 - "Total knee arthroplasty in patients with stiff knees has substantially improved in the clinical outcome and the arc of motion." 05/01/2015 - "The aim of this study was to compare the maximum laxity conferred by the cruciate-retaining (CR) and posterior-stabilised (PS) Triathlon single-radius total knee arthroplasty (TKA) for anterior drawer, varus-valgus opening and rotation in eight cadaver knees through a defined arc of flexion (0º to 110º). " 09/01/2010 - "The purposes of this study were to (1) measure the functional articular arc in different sizes of currently available one-piece metal shells from several different manufacturers; and (2) compare the functional articular arc of these one-piece metal shells with the 180 masculine arc of conventional hip arthroplasty acetabular components. " 03/01/2008 - "This study assessed the reliability of 4 methods of measuring proximal migration after shoulder arthroplasty on standard anteroposterior radiographs: the glenohumeral center-to-center measure, the glenohumeral arc measure, the acromiohumeral distance, and the scapular spine-humeral head center (spinohumeral) distance. " 10/21/2015 - "Gap-balancing is an alignment method for total knee arthroplasty with the goal of creating uniform tension in the periarticular soft-tissue restraints and equal laxities throughout the arc of flexion. "