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Agnosia (Visual Agnosia)

Loss of the ability to comprehend the meaning or recognize the importance of various forms of stimulation that cannot be attributed to impairment of a primary sensory modality. Tactile agnosia is characterized by an inability to perceive the shape and nature of an object by touch alone, despite unimpaired sensation to light touch, position, and other primary sensory modalities.

Also Known As:

Visual Agnosia; Agnosia for Pain; Agnosia for Smell; Agnosia for Taste; Agnosia for Temperature; Auditory Agnosia, Congenital; Body-Image Agnosia; Congenital Auditory Agnosia; Developmental Agnosia; Ideational Agnosia; Olfactory Agnosia; Position Agnosia; Somatosensory Agnosia; Time Agnosia; Topographical Agnosia; Visual Agnosia for Objects; Visual Disorientation Syndrome; Visuospatial Agnosia; Agnosia for Tastes; Agnosia, Auditory; Agnosia, Body-Image; Agnosia, Congenital Auditory; Agnosia, Developmental; Agnosia, Finger; Agnosia, Ideational; Agnosia, Olfactory; Agnosia, Position; Agnosia, Sensory; Agnosia, Somatosensory; Agnosia, Tactile; Agnosia, Time; Agnosia, Topographical; Agnosia, Visual; Agnosia, Visuospatial; Agnosias; Agnosias, Auditory; Agnosias, Body-Image; Agnosias, Congenital Auditory; Agnosias, Developmental; Agnosias, Finger; Agnosias, Ideational; Agnosias, Olfactory; Agnosias, Position; Agnosias, Sensory; Agnosias, Somatosensory; Agnosias, Tactile; Agnosias, Time; Agnosias, Topographical; Agnosias, Visual; Agnosias, Visuospatial; Auditory Agnosias; Auditory Agnosias, Congenital; Body Image Agnosia; Body-Image Agnosias; Congenital Auditory Agnosias; Developmental Agnosias; Finger Agnosias; Ideational Agnosias; Olfactory Agnosias; Position Agnosias; Sensory Agnosias; Somatosensory Agnosias; Syndrome, Visual Disorientation; Syndromes, Visual Disorientation; Tactile Agnosias; Time Agnosias; Topographical Agnosias; Visual Agnosias; Visual Disorientation Syndromes; Visuospatial Agnosias; Auditory Agnosia; Finger Agnosia; Sensory Agnosia; Tactile Agnosia

Networked: 52 relevant articles (2 outcomes, 5 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Apraxias (Dyspraxia)
2.	Aphasia (Dysphasia)
3.	Landau-Kleffner Syndrome
4.	Carbon Monoxide Poisoning (Poisoning, Carbon Monoxide)
5.	Stroke (Strokes)

Experts

1.	Takaiwa, Akiko: 2 articles (08/2006 - 11/2005)
2.	Kelz, Max B: 1 article (06/2015)
3.	DiPuppo, Patricia M: 1 article (06/2015)
4.	Cook-Sather, Scott D: 1 article (06/2015)
5.	Drobish, Julie K: 1 article (06/2015)
6.	Yuan, Yun: 1 article (04/2015)
7.	Leng, Yinglin: 1 article (04/2015)
8.	Wang, Zhaoxia: 1 article (04/2015)
9.	Liu, Yuhe: 1 article (04/2015)
10.	Fang, Xiaojing: 1 article (04/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Agnosia:

1.	Valproic Acid (Valproate, Semisodium)FDA LinkGeneric 05/01/1992 - "Auditory agnosia was correlated well with EEG abnormalities, and valproic acid and clonazepam were effective for EEG improvement. " 09/01/2004 - "Although spike discharges on the scalp EEGs disappeared by treatment with clonazepam and sodium valproate, the auditory agnosia did not improve. "
2.	Clonazepam (Rivotril)FDA LinkGeneric 05/01/1992 - "Auditory agnosia was correlated well with EEG abnormalities, and valproic acid and clonazepam were effective for EEG improvement. " 09/01/2004 - "Although spike discharges on the scalp EEGs disappeared by treatment with clonazepam and sodium valproate, the auditory agnosia did not improve. "
3.	Risperidone (Risperdal Consta)FDA LinkGeneric 09/01/2003 - "To determine whether risperidone, olanzapine, and haloperidol were differentially effective in reducing autonoetic agnosia and whether changes in this aspect of cognition were related to reduction of specific symptoms of psychosis. " 09/01/2003 - "From a cohort of 49 patients diagnosed with schizophrenia by DSM-IV criteria and randomly assigned to double-blind treatment with risperidone, olanzapine, or haloperidol, 16 patients were identified with symptoms believed to reflect autonoetic agnosia ("target symptoms") as assessed with the Schneiderian Symptom Rating Scale, and then evaluated during a baseline period, and then at 1, 2, and 3 weeks. "
4.	Haloperidol (Haldol)FDA LinkGeneric 09/01/2003 - "To determine whether risperidone, olanzapine, and haloperidol were differentially effective in reducing autonoetic agnosia and whether changes in this aspect of cognition were related to reduction of specific symptoms of psychosis. " 09/01/2003 - "From a cohort of 49 patients diagnosed with schizophrenia by DSM-IV criteria and randomly assigned to double-blind treatment with risperidone, olanzapine, or haloperidol, 16 patients were identified with symptoms believed to reflect autonoetic agnosia ("target symptoms") as assessed with the Schneiderian Symptom Rating Scale, and then evaluated during a baseline period, and then at 1, 2, and 3 weeks. "
5.	olanzapine (Zyprexa)FDA Link 09/01/2003 - "To determine whether risperidone, olanzapine, and haloperidol were differentially effective in reducing autonoetic agnosia and whether changes in this aspect of cognition were related to reduction of specific symptoms of psychosis. " 09/01/2003 - "From a cohort of 49 patients diagnosed with schizophrenia by DSM-IV criteria and randomly assigned to double-blind treatment with risperidone, olanzapine, or haloperidol, 16 patients were identified with symptoms believed to reflect autonoetic agnosia ("target symptoms") as assessed with the Schneiderian Symptom Rating Scale, and then evaluated during a baseline period, and then at 1, 2, and 3 weeks. "
6.	CoalIBA 11/01/2005 - "We re-evaluated a case of carbon monoxide poisoning presenting as visual agnosia who had been injured by explosion of Miike-Mikawa coal mine 40 years ago. " 11/01/2005 - "[A case of carbon monoxide poisoning by explosion of coal mine presenting as visual agnosia: re-evaluation after 40 years]." 01/01/1974 - "[A clinical study on acute carbon monoxide poisoning residuals due to explosive accidents in coal mines with special reference to neuropsychologic signs (aphasia, apraxia, agnosia and mental signs) (author's transl)]." 09/01/1969 - "[Psychiatric signs, aphasia, apraxia and agnosia in acute carbon monoxide poisoning, with special reference to experiences in coal mine explosions]."
7.	Technetium Tc 99m Exametazime (Ceretec)FDA Link 10/01/1992 - "We obtained 99mTc-HMPAO SPECT studies in five children with LKS and in three children with syndromes of verbal-auditory agnosia. "
8.	Anticonvulsants (Antiepileptic Drugs)IBA 05/01/1984 - "Prospective trials of anticonvulsant drugs in conjunction with serial measures of central auditory abilities are necessary to establish their value in the management of the linguistic deficit in children with auditory agnosia."
9.	4- N,N- dimethylamino- 1- naphthylisothiocyanateIBA 07/01/2005 - "Our data also indicate that the unusual clinical signs of DNTC reported by several Japanese researchers, including parietal signs such as apraxia and agnosia, are roughly consistent with the topographic distribution of cerebral cortical lesions in DNTC elucidated in this study."
10.	Carbon MonoxideIBA 07/31/2013 - "The human individual DF received a toxic exposure to carbon monoxide some years ago, which resulted in a persisting visual-form agnosia that has been extensively characterized at the behavioral level. " 01/01/2012 - "Our results document, for the first time, the co-occurrence of body agnosia, i.e. " 01/01/2002 - "We also suggest that integrative visual agnosia co-occurs with a category-specific impairment for living things because the recognition of these items requires more global processing than for non-living things. " 04/01/1991 - "On comparison with previously reported cases, our results support the hypothesis that carbon monoxide toxicity can induce a visual agnosia of the apperceptive type with well defined characteristics, seldom seen with other types of cerebral injury. " 04/01/1991 - "In one of the seminal works on visual agnosia, Adler (1944, 1950) presented the case of a 22-yr-old woman who sustained carbon monoxide cerebral toxicity in the Cocoanut Grove nightclub diaster of 1942. "

Therapies and Procedures

1.	Sign Language 08/01/2009 - "This article reviews the history of sign language (SL) and the rationale for its use in children with profound auditory agnosia due to Landau-Kleffner syndrome (LKS), illustrated by studies of children and adults followed for many years and rare cases from the literature. " 07/01/1998 - "We report a 27-year-old woman with chronic auditory agnosia following Landau-Kleffner Syndrome (LKS) diagnosed at age 4 1/2. She grew up in the hearing/speaking community with some exposure to manually coded English and American Sign Language (ASL). "
2.	Split-Brain Procedure (Split-Brain) 09/01/2007 - "In this review article, the author tries to emphasize the localization relationship between focal brain lesions and language dysfunction, by discussing from split-brain syndromes, hemispheric asymmetry, to pure word dumbness, pure word deafness (verbal auditory agnosia), pure agraphia, and pure word blindness (pure alexia; visual word agnosia), and finally to aphasia and aprosodia in general. "
3.	Anterior Temporal Lobectomy 01/01/1995 - "A 70-year-old right-handed woman developed a complete Klüver-Bucy syndrome including psychic blindness, aberrant sexual behavior, hypermetamorphosis, aphasia and visual agnosia following left anterior temporal lobectomy for an anaplasic oligodendroglioma. "
4.	Occupational Therapy (Therapy, Occupational) 06/01/2005 - "In response to these limitations, a battery of items, called the Occupational Therapy Adult Perceptual Screening Test (OT-APST) was selected to screen adults comprehensively for impairments of agnosia, visuospatial skills including body scheme and neglect, constructional skills, apraxia, and acalculia. "
5.	Lipreading (Lip Reading) 02/01/1991 - "Speech discrimination and lip reading in patients with word deafness or auditory agnosia." 02/01/1991 - "Our results show that patients with word deafness or auditory agnosia without aphasia can improve speech comprehension by reading lips in combination with listening, as compared with lip reading or listening alone. "