Afferent Loop Syndrome

A complication of gastrojejunostomy (BILLROTH II PROCEDURE), a reconstructive GASTROENTEROSTOMY. It is caused by acute (complete) or chronic (intermittent) obstruction of the afferent jejunal loop due to HERNIA, intussusception, kinking, VOLVULUS, etc. It is characterized by PAIN and VOMITING of BILE-stained fluid.

Also Known As:

Networked: 67 relevant articles (0 outcomes, 2 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Jaundice
2.	Vomiting
3.	Stomach Neoplasms (Stomach Cancer)
4.	Cholangitis
5.	Carcinoma (Carcinomatosis)

Experts

1.	Kim, Seong Hyun: 2 articles (11/2013 - 02/2012)
2.	Lee, Don Haeng: 2 articles (11/2013 - 02/2012)
3.	Jeong, Seok: 2 articles (11/2013 - 02/2012)
4.	Yook, Jeong Hwan: 2 articles (12/2012 - 12/2007)
5.	Song, Ho-Young: 2 articles (12/2012 - 12/2007)
6.	Kim, Jin Hyoung: 2 articles (12/2012 - 12/2007)
7.	Tajiri, Takashi: 2 articles (08/2006 - 05/2005)
8.	Kassir, Radwan: 1 article (10/2015)
9.	Lointier, Patrice: 1 article (10/2015)
10.	Tiffet, Olivier: 1 article (10/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Afferent Loop Syndrome:

1.	BariumIBA 03/01/2007 - "Clinically, the diagnosis of afferent loop syndrome may be difficult to establish and thus, depends on the finding of computed tomography, abdominal ultrasound, barium studies and hepatobiliary scan. "
2.	AmylasesFDA Link 01/01/1960 - "Serum amylase levels in experimental intestinal obstruction with special reference to the acute afferent loop syndrome." 07/01/2014 - "Initially, he was diagnosed with acute pancreatitis because of an elevated amylase level and pain, but was finally diagnosed with acute afferent loop syndrome when an impacted enterolith was identified by computed tomography. "
3.	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 10/01/1975 - "[Effect of antibiotics on the assimilation of exogenic vitamin B 12 and iron in patients with afferent loop syndrome]."
4.	IronIBA 10/01/1975 - "[Effect of antibiotics on the assimilation of exogenic vitamin B 12 and iron in patients with afferent loop syndrome]."
5.	Fluorouracil (Carac)FDA LinkGeneric 07/01/2002 - "Non-surgical treatment for afferent loop syndrome in recurrent gastric cancer complicated by peritoneal carcinomatosis: percutaneous transhepatic duodenal drainage followed by 24-hour infusion of high-dose fluorouracil and leucovorin."
6.	Leucovorin (Folinic Acid)FDA Link 07/01/2002 - "Non-surgical treatment for afferent loop syndrome in recurrent gastric cancer complicated by peritoneal carcinomatosis: percutaneous transhepatic duodenal drainage followed by 24-hour infusion of high-dose fluorouracil and leucovorin."
7.	Barium Sulfate (Barite)IBA 10/01/1993 - "Dynamic scintigraphy of stomach is useful for studying evacuative function of the resected stomach and for afferent loop syndrome diagnosis, which sometimes is more informative than a wide-spread barium sulfate roentgenological method."
8.	Anti-Bacterial Agents (Antibiotics)IBA 10/01/1975 - "[Effect of antibiotics on the assimilation of exogenic vitamin B 12 and iron in patients with afferent loop syndrome]."
9.	Eosinophilic enteropathyIBA 06/01/1990 - "It helps to differentiate eosinophilic gastroenteritis from regional enteritis and lymphoma, displays a typical appearance in intussusception and is quite specific in the afferent loop syndrome, closed-loop obstruction and lymphedema. "
10.	lidofenin (HIDA)IBA 08/01/1984 - "Technetium-99m HIDA hepatobiliary scanning represents the only diagnostic means of afferent loop syndrome definition. " 08/01/1984 - "Technetium-99m HIDA hepatobiliary scanning in evaluation of afferent loop syndrome."

Therapies and Procedures

1.	Enterostomy 08/01/2002 - "The purpose of this study was to investigate the clinical effectiveness of percutaneous tube enterostomy in afferent loop syndrome presenting as jaundice. " 08/01/2002 - "Palliative percutaneous tube enterostomy in afferent-loop syndrome presenting as jaundice: clinical effectiveness." 08/01/2002 - "Percutaneous tube enterostomy is an effective palliative treatment in afferent loop syndrome presenting as an obstructing jaundice. "
2.	Gastrectomy 10/01/2015 - "Afferent loop syndrome is encountered less frequently now that the number of gastrectomies has dropped. " 01/01/2009 - "Afferent loop syndrome is quite uncommon, and must be suspected in patients who have undergone subtotal gastrectomy. " 01/01/2009 - "Afferent loop syndrome is a relatively rare complication after subtotal gastrectomy. " 02/01/2004 - "CT findings of afferent loop syndrome after a subtotal gastrectomy with Roux-en-Y reconstruction." 01/01/2003 - "Following gastrectomy, stasis in the afferent jejunal loop accompanied by an overgrowth of bacteria leads to a number of clinical symptoms, including the so-called afferent loop syndrome. "
3.	Gastroenterostomy 10/01/2015 - "The omega loop procedure is associated with a risk of afferent loop syndrome, a known complication of the Billroth II (Finsterer) operation. " 07/01/2011 - "Using multidetector-row CT for the diagnosis of afferent loop syndrome following gastroenterostomy reconstruction." 01/01/2009 - "Patients with resection of stomach and especially with Billroth II reconstruction (gastro jejunal anastomosis), are more likely to develop afferent loop syndrome which is a rare complication. " 01/01/1976 - "The morphological changes in the liver and pancreas during the first 12 hours in the acute afferent loop syndrome were studied in rats with a Billroth II gastric resection. " 05/01/2013 - "Enterolith causing acute afferent loop syndrome after Billroth II gastrectomy: a case report."
4.	Gastric Bypass (Roux-en-Y Gastric Bypass) 10/01/2015 - "Laparoscopic Revision of an Omega Loop Gastric Bypass to Treat Afferent Loop Syndrome." 07/01/2015 - "Afferent loop syndrome (ALS) is a recognised complication of foregut surgery caused by mechanical obstruction at the gastrojejunostomy anastomosis itself or at a point nearby. " 09/01/2011 - "Afferent loop syndrome is a rare complication of gastrojejunostomy. " 06/01/2000 - "Afferent loop syndrome is caused by intermittent mechanical obstruction of the afferent loop of a gastrojejunostomy and may present early as an acute type or late as a chronic type. " 07/01/2015 - "One-step EUS-guided gastrojejunostomy with use of lumen-apposing metal stent for afferent loop syndrome treatment."
5.	Stents 12/01/2012 - "Placement of partially covered dual stents appears to be a promising technique that may offer successful palliation for patients who develop afferent loop syndrome after various types of surgery." 12/01/2012 - "Data from 13 consecutive patients who had undergone partially covered dual stent placement for afferent loop syndrome after various types of surgery were retrospectively analyzed. " 12/01/2012 - "The purpose of this article is to assess the technical feasibility and clinical effectiveness of the placement of partially covered self-expandable dual stents in patients with afferent loop syndrome. " 12/01/2012 - "Afferent loop syndrome: treatment by means of the placement of dual stents." 07/01/2015 - "One-step EUS-guided gastrojejunostomy with use of lumen-apposing metal stent for afferent loop syndrome treatment."