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Intravesical Administration

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The instillation or other administration of drugs into the bladder, usually to treat local disease, including neoplasms.

Also Known As:

Administration, Intravesical; Administration, Intravesical Drug; Injections, Intravesical; Intravesical Injection; Intravesical Instillation; Administration, Bladder Drug; Administrations, Bladder Drug; Administrations, Intravesical; Administrations, Intravesical Drug; Bladder Drug Administrations; Bladder Instillation; Bladder Instillations; Drug Administration, Intravesical; Drug Administrations, Bladder; Drug Administrations, Intravesical; Injection, Intravesical; Instillation, Intravesical; Instillations, Bladder; Instillations, Intravesical; Intravesical Administrations; Intravesical Drug Administrations; Intravesical Injections; Intravesical Instillations; Bladder Drug Administration; Drug Administration, Bladder; Instillation, Bladder; Intravesical Drug Administration

Networked: 1150 relevant articles (122 outcomes, 174 trials/studies)

Relationship Network

Therapy Context: Research Results

Therapeutics: 15318
- Drug Therapy: 178671
  - Drug Administration Routes: 9
    - Topical Administration: 791
      - Intravesical Administration: 1150

Experts

1.	Bjorling, Dale E: 10 articles (04/2014 - 06/2007)
2.	Wang, Zun-Yi: 8 articles (04/2014 - 06/2007)
3.	Kikuchi, Eiji: 7 articles (07/2015 - 03/2004)
4.	Witjes, J Alfred: 7 articles (06/2015 - 09/2006)
5.	So, Alan I: 7 articles (01/2013 - 03/2008)
6.	Gleave, Martin E: 7 articles (05/2011 - 06/2004)
7.	de Witte, Peter A M: 7 articles (04/2011 - 11/2004)
8.	Kuo, Hann-Chorng: 6 articles (08/2015 - 01/2007)
9.	Oya, Mototsugu: 6 articles (07/2015 - 03/2009)
10.	Giannantoni, Antonella: 5 articles (12/2015 - 04/2006)

Related Diseases

1.	Urinary Bladder Neoplasms (Bladder Cancer) 10/01/2008 - "Intravesical instillation of BCG is the most effective in the long term when chosen as the initial prophylactic therapy for the prevention of recurrence in superficial bladder cancer." 07/01/2006 - "Intravesical instillation of Bacillus Calmette-Guérin (BCG) after transurethral resection is the most effective treatment for superficial bladder cancers. " 06/01/2003 - "The data suggest that intravesical instillation of BCG is more effective when no prior treatment has been attempted, and that best results may be achieved if BCG is chosen as the initial therapy for superficial bladder cancer. " 12/01/1990 - "Intravesical administration of bacillus Calmette-Guerin has been shown to be highly effective treatment of superficial bladder cancer. " 10/01/1986 - "Intravesical instillation of bacille Calmette Guerin (BCG) currently is considered the most effective treatment for recurrent superficial bladder cancer, but little is known about the mechanism of action. "
2.	Neoplasms (Cancer) 05/01/1997 - "Our multi-institutional studies revealed that the direct efficacy of BCG, intravesical instillation for treatment of an existing tumor is very promising. " 01/01/1987 - "The following conclusions are derived: 1) If bladder instillation therapy aims only at complete remission (CR), tumors over 1 cm in diameter should be excluded, because this is the theoretical size limit beyond which instillation therapy cannot lead to CR. " 01/01/1993 - "In numerous studies, involving over 3,000 patients, intravesical instillation of BCG has been shown to be an effective treatment for superficial cancer of the urinary bladder in humans. " 11/01/2008 - "Early use of single intravesical instillation of HYD plus subsequent regular intravesical instillation of BCG is markedly effective for preventing postoperative recurrence of bladder transitional cell cancer, with few adverse events." 01/01/1989 - "Intravesical instillations of BCG are effective in preventing tumor recurrence, eliminating existing tumor and treating CIS in a substantial number of patients. "
3.	Carcinoma (Carcinomatosis) 03/01/1994 - "Immunotherapy with intravesical instillation of bacillus Calmette-Guérin (BCG) is an effective treatment for superficial bladder carcinoma. " 03/01/1993 - "Intravesical administration of bacillus Calmette-Guerin (BCG) is an effective treatment for superficial carcinoma of the bladder. " 02/01/1993 - "Intravesical administration of Calmette-Guérin bacillus (BCG) is effective in the treatment of superficial bladder carcinoma. " 06/01/1996 - "Superficial bladder carcinoma, treated by resection and intravesical administration of bacillus Calmette-Guérin (BCG), yields a remission rate that approaches 70%. " 11/01/2012 - "In the present prospective single-center study with a same-patient comparison, patients with suspected urothelial cell carcinoma underwent surgical exploration after receiving a bladder instillation of HAL. "
4.	Cystitis 10/01/2015 - "The intravesical instillation of HA + CS is more effective than long-term antibiotic prophylaxis for preventing recurrent bacterial cystitis." 10/01/2014 - "Intravesical instillation of GTE attenuated the inflammatory response to UPEC-SR71-induced bacterial cystitis and is a novel approach to the treatment of bacterial cystitis. " 10/01/2014 - "Intravesical instillation of GTE attenuated the inflammatory response to UPEC-SR71-induced bacterial cystitis in this rat model. " 10/01/2014 - "In vivo effects of intravesical instillation of GTE on bacterial cystitis was analysed using a rat model of bacterial cystitis. " 08/01/2012 - "Intravesical instillation of EPI preserves UPII expression and attenuates the toxic responses in the bladder in CYP-induced rat cystitis."
5.	Interstitial Cystitis (Interstitial Cystitis, Chronic) 04/01/2006 - "The results of this pilot study indicate that BTX-A intravesical injections are effective in the short-term management of painful bladder syndrome. " 03/01/1998 - "A psychometric analysis of the University of Wisconsin Interstitial Cystitis Scale was conducted on 30 females previously enrolled in a phase II double-blind randomized controlled trial evaluating the efficacy of six weekly intravesical instillations of TICE BCG. " 02/01/2013 - "Is there enough evidence for the use of intravesical instillations of glycosaminoglycan analogues in interstitial cystitis?" 08/01/2012 - "In male Sprague-Dawley rats, interstitial cystitis was induced by intravesical instillation of protamine sulphate (2 mg in 200 μl saline for 30 min; n = 6). " 08/01/2006 - "Localization of the FGF-10 receptor to the superficial urothelial layer is clinically significant because intravesical administration of FGF-10 may provide the clinician a means to control the turnover of transitional epithelium in bladder disorders such as interstitial cystitis."

Related Drugs and Biologics

1.	Doxorubicin (Adriamycin)
2.	Epirubicin (Ellence)
3.	Thiotepa (Triethylenethiophosphoramide)
4.	gemcitabine
5.	Hyaluronic Acid (Hyaluronan)
6.	Mitomycin (Mitomycin-C)
7.	pirarubicin
8.	Botulinum Toxins (Botulinum Toxin)
9.	oxybutynin (Tavor)
10.	Dimethyl Sulfoxide (DMSO)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Radiotherapy
3.	Immunotherapy
4.	Oral Administration
5.	Injections