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Intranasal Administration

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The administration of drugs through the nasal passage.

Also Known As:

Administration, Intranasal; Administration, Intranasal Drug; Intranasal Drug Administration; Administrations, Intranasal; Administrations, Intranasal Drug; Drug Administrations, Intranasal; Intranasal Administrations; Intranasal Drug Administrations; Drug Administration, Intranasal

Networked: 694 relevant articles (70 outcomes, 72 trials/studies)

Relationship Network

Therapy Context: Research Results

Therapeutics: 15318
- Drug Therapy: 178671
  - Drug Administration Routes: 9
    - Topical Administration: 791
      - Intranasal Administration: 694
    - Intranasal Administration: 694

Experts

1.	Hasegawa, Hideki: 8 articles (11/2015 - 01/2002)
2.	Andreeva, L A: 8 articles (11/2014 - 06/2003)
3.	Liu, Xin-Feng: 7 articles (04/2013 - 05/2008)
4.	Frey, William H: 6 articles (06/2012 - 01/2007)
5.	Takahashi, Hidehiro: 6 articles (10/2010 - 01/2002)
6.	Kurata, Takeshi: 6 articles (10/2010 - 01/2002)
7.	Sata, Tetsutaro: 6 articles (10/2010 - 01/2002)
8.	Liu, Xinfeng: 5 articles (11/2015 - 01/2008)
9.	Shubina, T A: 5 articles (11/2014 - 07/2012)
10.	Myasoedov, N F: 5 articles (11/2014 - 12/2006)

Related Diseases

1.	Infection 10/01/2014 - "Intranasal administration of Mycobacterium bovis BCG induces superior protection against aerosol infection with Mycobacterium tuberculosis in mice." 10/08/2010 - "Here we evaluated the immunogenicity and the protective efficacy of R345V against SIV infection by intranasal administration, the more practical route for vaccination of pigs in the field. " 11/01/2011 - "Intranasal administration of ABLC for prophylaxis of invasive fungal infection in immunocompromised patients is safe and appears to be a promising treatment strategy for the future. " 01/01/2012 - "Intranasal administration of live Lactobacillus species facilitates protection against influenza virus infection in mice." 01/04/2007 - "Intranasal administration of chlamydial outer protein N (CopN) induces protection against pulmonary Chlamydia pneumoniae infection in a mouse model."
2.	Human Influenza (Influenza) 09/01/2013 - "In 2012, a live attenuated vaccine for intranasal administration was authorised in the European Union for influenza prevention in individuals aged from 2 to less than 18 years. " 07/01/2012 - "All volunteers underwent intranasal administration of influenza A/Wisconsin/67/2005 while in a quarantine unit and were monitored for symptoms of influenza disease and virus shedding. " 01/01/2012 - "Mice received two doses of influenza split vaccine with oil-in-water emulsion adjuvant SP01 by intranasal administration separated by two weeks. " 10/01/2010 - "Intranasal administration of adjuvant-combined vaccine protects monkeys from challenge with the highly pathogenic influenza A H5N1 virus." 01/01/2009 - "Here, we report that intranasal administration of purified gamma-ray inactivated human influenza A virus preparations (gamma-Flu) effectively induces heterotypic and cross-protective immunity. "
3.	Rhinitis 11/01/2012 - "Clinical signs of rhinitis were significantly (p < 0.01) relieved after a single intranasal administration of RT001 and resolved to normal baseline levels within 5 days after treatment. " 06/01/2012 - "Intranasal administration is a non-invasive route for drug delivery, which is widely used for the local treatment of rhinitis or nasal polyposis. " 01/01/2012 - "An antagonist for CCR4 alleviates murine allergic rhinitis by intranasal administration." 10/01/2011 - "Intranasal administration of CD30-Ig during the effector phase with OVA significantly prevented the development of allergic rhinitis in WT mice. " 04/14/2011 - "The discovery of phthalazinone-based human H1 and H3 single-ligand antagonists suitable for intranasal administration for the treatment of allergic rhinitis."
4.	Eosinophilia 10/01/2000 - "Intranasal administration of anti-IL-5 also reduced BAL eosinophilia, partly via local effects in the airways. " 06/01/2000 - "Intranasal administration of Mycobacterium bovis-Bacillus Calmette-Guerin (BCG) has been demonstrated to suppress airway eosinophilia in a model of atopic asthma. " 08/01/2013 - "Intranasal administration of Gcf induced antibody response and increased IFNγ secretion and protected mice against RSV challenge without severe lung eosinophilia, even in the presence of high levels of RSV-specific maternal antibodies. " 04/01/2003 - "PGD(2) is known to induce eosinophilia following intranasal administration, and to induce eosinophil activation in vitro. " 03/15/1998 - "Intranasal administration of either Ad/TNFalpha or Ad/IL-4 into OVA-sensitized and -challenged CD40L-KO mice did not reconstitute airway eosinophilia. "
5.	Pneumonia (Pneumonitis) 03/01/2006 - "Therefore, in the present study we sought to determine the function of pulmonary LBP in lung inflammation induced by intranasal administration of LPS in vivo. " 11/01/2015 - "We induced acute lung inflammation through intranasal administration of E. " 10/01/2015 - "In our murine experiments, a single intranasal administration of YH6 (2 × 10(7) PFU) 2 h after D9 intranasal injections at double minimum lethal dose was sufficient to protect mice against hemorrhagic pneumonia. " 09/01/2015 - "Collectively, these results suggest that intranasal administration of V. cholerae leading to acute pneumonia elicited alterations of protein profiles associated with immune homeostasis and host protection in both the mucosal and systemic compartments. " 01/01/2015 - "Intranasal administration of a single dose of 2×10(9) PFU/mouse 2 h after KP 1513 inoculation was able to protect mice against lethal pneumonia. "

Related Drugs and Biologics

1.	Antigens
2.	Immunoglobulin E (IgE)
3.	Liposomes (Liposome)
4.	Deamino Arginine Vasopressin (Desmopressin)
5.	DNA (Deoxyribonucleic Acid)
6.	Sumatriptan (Imigran)
7.	Immunoglobulin G (IgG)
8.	Immunoglobulin A (IgA)
9.	Hemagglutinins (Hemagglutinin)
10.	Antibodies

Related Therapies and Procedures

1.	Injections
2.	Chemoprevention
3.	Aftercare (After-Treatment)
4.	Topical Administration
5.	Heterologous Transplantation (Xenotransplantation)