Buccal Administration

Administration of a soluble dosage form between the cheek and gingiva. It may involve direct application of a drug onto the buccal mucosa, as by painting or spraying.

Also Known As:

Administration, Buccal; Administration, Buccal Drug; Administrations, Buccal; Administrations, Buccal Drug; Buccal Administrations; Buccal Drug Administrations; Drug Administrations, Buccal; Buccal Drug Administration; Drug Administration, Buccal

Networked: 33 relevant articles (3 outcomes, 5 trials/studies)

Relationship Network

Therapy Context: Research Results

Therapeutics: 1158551
- Drug Therapy: 293145
  - Drug Administration Routes: 28
    - Oral Administration: 17836
      - Buccal Administration: 33
    - Topical Administration: 1420
      - Buccal Administration: 33

Experts

1.	Fjerstad, Mary: 3 articles (03/2014 - 07/2009)
2.	Lichtenberg, E Steve: 3 articles (03/2014 - 07/2009)
3.	Trussell, James: 3 articles (03/2014 - 07/2009)
4.	Cullins, Vanessa: 2 articles (04/2011 - 07/2009)
5.	Sivin, Irving: 2 articles (04/2011 - 07/2009)
6.	Alaamery, Manal: 1 article (02/2022)
7.	Aldossary, Ahmad M: 1 article (02/2022)
8.	Alfahad, Ahmed J: 1 article (02/2022)
9.	Alfassam, Haya A: 1 article (02/2022)
10.	Almughem, Fahad A: 1 article (02/2022)

Related Diseases

1.	Asthma (Bronchial Asthma) 07/01/1985 - "Buccal administration of fenoterol may be a useful treatment for children with mild asthma who have difficulty in using inhaled drugs." 07/01/1985 - "Buccal administration of fenoterol aerosol in childhood asthma." 08/14/1976 - "Buccal administration of fenoterol aerosol in young children with asthma."
2.	Dyspnea (Shortness of Breath) 08/01/2021 - "We inadvertently discovered the efficacy of buccal administration of low dose, low volume hydromorphone oral syrup for dyspnea management in ILD, which has not been previously reported in the literature. "
3.	Body Weight (Weight, Body) 04/01/2005 - "Sixteen crossbred (British x Continental; average un-shrunk body weight = 507.9 kg; SD = 45.6 kg) beef heifers fed a steam-flaked corn-based finishing diet with melengestrol acetate (0.4 mg/heifer daily) included to suppress estrus were used in a completely random design to evaluate the efficacy of buccal administration of 0, 10, 100, or 1000 mg of 25-hydroxyvitamin D3, (25-OH D3). "
4.	Stomatitis 01/01/2018 - "Regarding the pharmacokinetic parameters, cats with stomatitis showed lower bioavailability and shorter absorption half-life after buccal administration of buprenorphine compared with normal cats in previous studies. " 01/01/2017 - "The purpose of this study was to formulate ketoprofen (KET)-loaded Eudragit L and Eudragit S nanofibers (NFs) by the electrospinning technique for buccal administration to treat oral mucositis as a safe alternative to orally administered KET, which causes gastrointestinal tract (GIT) side effects. "
5.	Vomiting 01/01/2022 - "Women may experience more vomiting with sublingual compared to buccal administration (RR 1.33, 95% CI 1.01 to 1.77; low-certainty evidence). " 12/01/2005 - "Buccal administration of prochlorperazine, twice daily, should enhance the therapeutic role of prochlorperazine in preventing and treating nausea and vomiting." 04/30/2020 - "The objective of this study was the development of different solid formulations, such as wafers and films, for buccal administration of ondansetron, a selective and potent antagonist of 5-hydroxytryptamine 3 receptors used in children for the treatment of nausea and vomiting. "

Related Drugs and Biologics

1.	Fenoterol
2.	Steam
3.	Melengestrol Acetate (Melengestrol)
4.	Hydromorphone (Dilaudid)
5.	Calcifediol (Calcidiol)
6.	Buprenorphine (Subutex)
7.	Ondansetron (Zofran)
8.	Tablets
9.	Serotonin (5 Hydroxytryptamine)
10.	Ritodrine (Yutopar)

Related Therapies and Procedures

1.	Therapeutics
2.	Intramuscular Injections
3.	Parenteral Infusions
4.	Cardiopulmonary Bypass (Heart-Lung Bypass)
5.	Rectal Administration