Cyclic AMP (AMP, Cyclic)

An adenine nucleotide containing one phosphate group which is esterified to both the 3'- and 5'-positions of the sugar moiety. It is a second messenger and a key intracellular regulator, functioning as a mediator of activity for a number of hormones, including epinephrine, glucagon, and ACTH.
Also Known As:
AMP, Cyclic; Adenosine Cyclic 3,5 Monophosphate; Adenosine Cyclic Monophosphate; Adenosine Cyclic-3',5'-Monophosphate; Cyclic AMP, (R)-Isomer; Cyclic AMP, Disodium Salt; Cyclic AMP, Monoammonium Salt; Cyclic AMP, Monopotassium Salt; Cyclic AMP, Monosodium Salt; Cyclic AMP, Sodium Salt; 3',5'-Monophosphate, Adenosine Cyclic; Adenosine Cyclic 3',5' Monophosphate; Cyclic 3',5'-Monophosphate, Adenosine; Cyclic Monophosphate, Adenosine; Cyclic-3',5'-Monophosphate, Adenosine; Monophosphate, Adenosine Cyclic; Adenosine Cyclic 3',5'-Monophosphate; Adenosine, cyclic 3',5'-(hydrogen phosphate)
Networked: 3171 relevant articles (46 outcomes, 184 trials/studies)

Relationship Network

Bio-Agent Context: Research Results


1. Stratakis, Constantine A: 17 articles (01/2020 - 10/2002)
2. Insel, Paul A: 8 articles (01/2020 - 07/2002)
3. Schmidt, Martina: 8 articles (01/2018 - 08/2004)
4. Bertherat, Jérôme: 7 articles (09/2009 - 01/2002)
5. Horvath, Anelia: 6 articles (08/2013 - 07/2006)
6. Groussin, Lionel: 6 articles (09/2009 - 11/2002)
7. Zhang, Han-Ting: 5 articles (01/2018 - 10/2010)
8. Lugnier, Claire: 5 articles (01/2012 - 02/2003)
9. Bertagna, Xavier: 5 articles (06/2008 - 01/2002)
10. Aguiar, Ricardo C T: 4 articles (01/2022 - 11/2011)

Related Diseases

1. Ischemia
02/01/1980 - "The cyclic AMP level in epidermis of psoriatic patients was reappraised with a highly sensitive radioimmunoassay method in conjunction with an improved skin biopsy technique to avoid any artificial rise of cyclic AMP due to ischemia. "
11/01/1979 - "Whether the ischemia-produced increase in cardiac beta-receptor content is causally related to increased cyclic AMP levels that develop in ischemic tissue and/or an etiologic factor in arrhythmias originating from ischemic myocardial tissue will have to be determined in additional studies."
01/01/1999 - "Such impairment of signal transduction may not be restored in the caudate-putamen even when cerebral circulation is fully recovered after short-term ischemia, suggesting that a regional vulnerability to ischemic stress may also exist in cyclic AMP-mediated signal transduction. "
01/01/1999 - "These data indicate that cyclic AMP-mediated signal transduction in the brain tissue may be very susceptible to ischemic stress, and the region of disrupted signal transduction may expand progressively from the ischemic core to peri-ischemic regions in the acute phase of ischemia. "
01/01/1999 - "No threshold was noted at 3 h of ischemia, since cyclic AMP binding showed a large variation ranging from reduced to normal values even when local cerebral blood flow was below 20 ml/100 g per min. Recirculation for 3.5 h following 1.5 h of ischemia restored the normal cyclic AMP binding in the cerebral cortices, but failed to normalize cyclic AMP binding in the caudate-putamen despite good recovery of local cerebral blood flow. "
2. Neoplasms (Cancer)
3. Neuroblastoma
4. Psoriasis (Pustulosis Palmaris et Plantaris)
5. Ventricular Fibrillation

Related Drugs and Biologics

1. Alprostadil (Muse)
2. Epinephrine (Adrenaline)
3. Calcium
4. Adenylyl Cyclases (Adenylyl Cyclase)
5. Colforsin
6. Bucladesine
7. Transcription Factors (Transcription Factor)
8. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
9. Insulin (Novolin)
10. Propranolol (Inderal)

Related Therapies and Procedures

1. Ligation
2. Therapeutics
3. Aftercare (After-Treatment)
4. Intramuscular Injections
5. Sutures (Suture)