An adrenal disease characterized by the progressive destruction of the ADRENAL CORTEX, resulting in insufficient production of ALDOSTERONE and HYDROCORTISONE. Clinical symptoms include ANOREXIA; NAUSEA; WEIGHT LOSS; MUSCLE WEAKNESS; and HYPERPIGMENTATION of the SKIN due to increase in circulating levels of ACTH precursor hormone which stimulates MELANOCYTES.
Also Known As:
Addison's Disease; Addisons Disease; Primary Adrenal Insufficiency; Primary Adrenocortical Insufficiency; Primary Hypoadrenalism; Adrenal Insufficiency, Primary; Adrenocortical Insufficiencies, Primary; Adrenocortical Insufficiency, Primary; Disease, Addison; Hypoadrenalism, Primary; Hypoadrenalisms, Primary; Insufficiencies, Primary Adrenocortical; Insufficiency, Primary Adrenocortical; Primary Adrenocortical Insufficiencies