Adamantane

05/01/2008 - "This study shows a temporal correlation between increases in amantadane prescriptions and the prevalence of adamantane-resistant influenza A(H3N2) viruses in Hong Kong. "
06/01/2006 - "To study the incidence of adamantane resistance among influenza A (H3N2) viruses isolated from the mainland of China since 1989 through our influenza surveillance system, and to provide more information for the clinical usage of adamantane drugs. "
01/01/2015 - "Our findings indicate that the frequency and distribution of adamantane-resistant influenza variants varied among different HA subtypes, host species, years of isolation, and geographical areas. "
01/01/2015 - "To investigate the frequency and distribution of M2 gene mutations in adamantane-resistant influenza variants circulated in the world between 1902 and 2013, 31251 available M2 protein sequences from different HA-subtype influenza A viruses (H1-H17) were analyzed and adamantane resistance-associated mutations were compared (L26F, V27A, A30T, A30V, S31N, G34E, and L38F). "
07/01/2014 - "As examples, reassortment was key to the emergence of the 1957, 1968, and 2009 pandemics; the unusually severe influenza epidemics of 2003, 1951, and 1947; and the rise in adamantane resistance among currently circulating human H3N2 viruses. "

01/01/2010 - "Only three adamantane-resistant H5N1 viruses have been detected since 2003, when the first case of human H5N1 virus infection was detected in mainland China. "
01/01/2010 - "Adamantane-derived drugs have been used for treatment and prophylaxis of influenza A virus infection for many years worldwide. "
05/01/1983 - "[Inhibiting action of adamantane derivatives on chronic influenzal infection in a tissue culture]."
01/01/2008 - "Adamantane-resistant influenza A is an emerging problem, but infections caused by resistant and susceptible viruses have not been compared. "
01/01/2008 - "Adamantane-resistant influenza infection during the 2004-05 season."

02/11/2010 - "The low toxicity-high Fe mobilization efficacy of selected adamantane-based DFOB conjugates underscores the potential of these compounds to treat iron overload disease in patients with transfusional-dependent disorders such as beta-thalassemia."
02/11/2010 - "Conjugates of desferrioxamine B (DFOB) with derivatives of adamantane or with orally available chelators as potential agents for treating iron overload."

02/11/2010 - "The low toxicity-high Fe mobilization efficacy of selected adamantane-based DFOB conjugates underscores the potential of these compounds to treat iron overload disease in patients with transfusional-dependent disorders such as beta-thalassemia."

10/01/2015 - "It is proposed that adamantane could be a very useful setup sample for (1)H CRAMPS NMR as the two peaks are only resolved when the effects of RF inhomogeneity and phase transients are minimized. "
10/01/2015 - "Minimizing the effects of RF inhomogeneity and phase transients allows resolution of two peaks in the (1)H CRAMPS NMR spectrum of adamantane."
10/01/2015 - "Under these optimal conditions, it was possible to clearly resolve two signals in the (1)H CRAMPS NMR spectrum of adamantane arising from the CH and CH2 protons in the molecule. "