Actinium

A trivalent radioactive element and the prototypical member of the actinide family. It has the atomic symbol Ac, and atomic number 89. Its principal isotope is 227 and it decays primarily by beta-emission.

Networked: 9 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Cotruvo, Joseph A: 1 article (10/2021)
2.	Deblonde, Gauthier J-P: 1 article (10/2021)
3.	Dong, Ziye: 1 article (10/2021)
4.	Mattocks, Joseph A: 1 article (10/2021)
5.	Wooddy, Paul T: 1 article (10/2021)
6.	Zavarin, Mavrik: 1 article (10/2021)
7.	Arnold, Vasumathi Jayaraj: 1 article (07/2020)
8.	Arunpandiyan, Soundararajan: 1 article (07/2020)
9.	Kamaleshwaran, Koramadai Karuppusamy: 1 article (07/2020)
10.	Madhusairam, Raghunathan: 1 article (07/2020)

Related Diseases

1.	Neoplasms (Cancer) 10/22/2021 - "Actinium-based therapies could revolutionize cancer medicine but remain tantalizing due to the difficulties in studying and limited knowledge of Ac chemistry. " 01/01/2020 - "Literature for this systematic review was identified using a PubMed search: ("targeted alpha therapy" or "targeted alpha particle therapy") or (213-bismuth or bismuth-213 or 213Bi) or (225-actinium or actinium-225 or 225Ac) or (211-astatine or astatine-211 or 211At) or (212-lead or lead-212 or 212Pb) or (227-thorium or thorium-227 or 227Th) or (223-radium or radium-223 or 223Ra or alpharadin) and (malignancy or cancer). " 11/01/1998 - "Cancer mortality in 40,761 employees of three UK nuclear industry facilities who had been monitored for external radiation exposure was examined according to whether they had also been monitored for possible internal exposure to tritium, plutonium or other radionuclides (uranium, polonium, actinium or other unspecified). " 01/20/2023 - "All Cerenkov emitting radionuclides were either produced at Memorial Sloan Kettering Cancer Center (Carbon-11, 11 C; Fluorine-18, 18 F; Iodine-124, 124 I), from commercial sources such as Perkin Elmer (Phosphorous-32, 32 P; Yttrium-90, 90 Y), Bayer (Radium-223, 223 Ra, Xofigo), 3D-Imaging (Zirconium-89, 89 Zr), Nuclear Diagnostic Products (Iodine-131, 131 I), or from academic collaborators at Washington University at St. Louis (Copper-64, 64 Cu), University of Wisconsin (Bromine-76, 76 Br), MD Anderson Cancer Center (Yttrium-86, 86 Y), Brookhaven National Laboratory (Arsenic-72, 72 As; Thorium-227, 227 Th), or Oak Ridge National Laboratory (Cerium-134, 134 Ce, Actinium-225, 225 Ac), and Viewpoint Molecular Targeting (Lead-203, 203 Pb; Lead 212, 212 Pb). "
2.	Disease Progression 01/01/2023 - "A disease progression was observed and with the knowledge of a germline BRCA1 mutation, the patient was treated with TAT (Actinium-225 [225Ac]-DOTATATE) combined with olaparib. "
3.	Neuroendocrine Tumors (Neuroendocrine Tumor) 07/01/2020 - "Whole-body and Single-Photon Emission Computed Tomography/Computed Tomography Postpeptide Receptor Alpha Radionuclide Therapy Images of Actinium 225-Tetraazacyclododecanetetraacetic Acid-Octreotide as a Primary Modality of Treatment in a Patient with Advanced Rectal Neuroendocrine Tumor with Metastases."
4.	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 10/01/2011 - "Actinium- 225 has been developed into potent targeting drug constructs and is in clinical use against acute myelogenous leukemia. "
5.	Experimental Sarcoma 07/01/1952 - "[The comparative fixation of actinium K, of cesium 134 and of rubidium 86 in experimental sarcomas and granulomas in rats]."

Related Drugs and Biologics

1.	Radioisotopes (Radionuclides)
2.	Thorium
3.	Radium
4.	Octreotide (Sandostatin)
5.	Zirconium
6.	Yttrium
7.	Uranium
8.	Tritium
9.	Rubidium
10.	Polonium

Related Therapies and Procedures

1.	Therapeutics
2.	Castration