Acne Keloid (Acne Keloidalis)

A type of acneiform disorder in which secondary pyogenic infection in and around pilosebaceous structures ends in keloidal scarring. It manifests as persistent folliculitis of the back of the neck associated with occlusion of the follicular orifices. It is most often encountered in black or Asian men.

Also Known As:

Networked: 29 relevant articles (2 outcomes, 2 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Alopecia (Baldness)
2.	Folliculitis (Sycosis)
3.	Cicatrix (Scar)
4.	Cellulitis
5.	Tinea (Ringworm)

Experts

1.	Taylor, Susan C: 2 articles (10/2003 - 04/2003)
2.	Tosti, Antonella: 1 article (01/2015)
3.	Lindsey, Scott F: 1 article (01/2015)
4.	Pirmez, Rodrigo: 1 article (11/2014)
5.	Ramos-e-Silva, Marcia: 1 article (11/2014)
6.	Madu, Pamela: 1 article (08/2014)
7.	Kundu, Roopal V: 1 article (08/2014)
8.	Bonan, P: 1 article (04/2013)
9.	Moretti, S: 1 article (04/2013)
10.	Cannarozzo, G: 1 article (04/2013)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Acne Keloid:

1.	Clobetasol (Clobetasol Propionate)FDA LinkGeneric 06/01/2005 - "An open label study of clobetasol propionate 0.05% and betamethasone valerate 0.12% foams in the treatment of mild to moderate acne keloidalis."
2.	Betamethasone (Celestone)FDA Link 06/01/2005 - "An open label study of clobetasol propionate 0.05% and betamethasone valerate 0.12% foams in the treatment of mild to moderate acne keloidalis."
3.	Cyclosporine (Ciclosporin)FDA LinkGeneric 02/01/2001 - "Nuchal acne keloidalis associated with cyclosporin." 01/01/2009 - "Acne keloidalis of the scalp in a renal transplant patient treated with cyclosporine." 08/01/2000 - "Acne keloidalis in caucasian patients on cyclosporin following organ transplantation."
4.	CosmeticsIBA 01/01/2011 - "This case report reviews the management of a patient with tumor-stage acne keloidalis nuchae successfully treated with electrosurgical excision and secondary intention healing with excellent cosmetic results and no recurrence of the disease." 04/01/2003 - "Diseases of more cosmetic concern (eg, melasma, postinflammatory pigmentation, acne keloidalis nuchae, scalp and facial folliculitis, keloids, alopecias) occur more in skin of color than in white skin." 10/01/2003 - "Diseases of a more cosmetic nature have emerged over recent years and include the pigmentary disorders melasma and postinflammatory pigmentation, acne keloidalis nuchae, scalp and facial folliculitis, keloidal scarring, alopecia, and photoaging. "
5.	Keratosis follicularis spinulosa decalvansIBA 01/01/2008 - "Acne keloidalis nuchae has previously been described in one patient with keratosis follicularis spinulosa decalvans. " 11/01/2005 - "The association of keratosis follicularis spinulosa decalvans with acne keloidalis nuchae has not previously been described. " 11/01/2005 - "With clinical correlation, the diagnosis of keratosis follicularis spinulosa decalvans and concurrent acne keloidalis nuchae was made. " 11/01/2005 - "Keratosis follicularis spinulosa decalvans and acne keloidalis nuchae." 01/01/2008 - "We report another case of keratosis follicularis spinulosa decalvans with acne keloidalis nuchae and tufted hair folliculitis, thus further establishing this association."
6.	CollagenIBA 08/01/1993 - "Analysis of collagen composition in acne keloids." 11/01/1992 - "Collagen chain composition and collagen gene expression in acne keloids."
7.	Burnett Schwartz Berberian syndromeIBA 04/01/2003 - "Other notable common diagnoses included keratosis pilaris, tinea infection, hirsuitism, folliculitis keloidalis nuchae, viral warts, dermatosis papulosa nigra, and confluent and reticulate papillomatosis. " 11/01/2014 - "We discuss the epidemiology, clinicals, pathogenesis, and therapy of lichen planopilaris with its variants, discoid lupus erythematosus, folliculitis decalvans, dissecting folliculitis, acne keloidalis nuchae, pseudofolliculitis barbae, tinea capitis, tinea barbae, folliculitis of diverse causative factors and inflammatory follicular keratotic syndromes, ulerythema ophryogenes, atrophoderma vermiculatum, keratosis follicularis spinulosa decalvans, and folliculitis spinulosa decalvans. "
8.	TenascinIBA 05/01/1994 - "Because acne involves hyperproliferation of ductal keratinocytes, and rupture of the duct may occur during inflammation, the distribution of tenascin and fibronectin was investigated in acne lesions, and also in acne keloids. "
9.	Triamcinolone (Aristocort)FDA Link 04/01/1994 - "A comparison of intralesional triamcinolone and cryosurgery in the treatment of acne keloids."
10.	SteroidsIBA 01/01/2005 - "Acne keloidalis nuchae is usually treated with oral antibiotics, local antiseptics or intralesional steroids but with limited success. "

Therapies and Procedures

1.	Lasers (Laser) 09/01/2012 - "The efficacy of laser-assisted hair removal in the treatment of acne keloidalis nuchae; a pilot study." 09/01/2012 - "Laser-assisted hair removal causes miniaturization of hair shafts which are the principal contributors to inflammation in acne keloidalis nuchae (AKN). " 01/01/2005 - "Thus, after clearing bacterial infection, laser hair epilation can be used as the first line of therapy for treating papules of acne keloidalis nuchae. "
2.	Hair Removal (Depilation) 09/01/2012 - "The efficacy of laser-assisted hair removal in the treatment of acne keloidalis nuchae; a pilot study." 09/01/2012 - "Laser-assisted hair removal causes miniaturization of hair shafts which are the principal contributors to inflammation in acne keloidalis nuchae (AKN). " 01/01/2005 - "Thus, after clearing bacterial infection, laser hair epilation can be used as the first line of therapy for treating papules of acne keloidalis nuchae. "
3.	Semiconductor Lasers 01/01/2005 - "I assessed the efficacy of diode laser for treating the inflammatory and keloidal papules of acne keloidalis nuchae in two cases. " 01/01/2005 - "Efficacy of diode laser for treating acne keloidalis nuchae." 01/01/2005 - "This is the first attempt at treating acne keloidalis nuchae with a diode laser."
4.	Traction 03/01/2006 - "Three studies of people of African ancestry found a prevalence of acne keloidalis nuchae ranging from 1.3% to 13.7% and of traction alopecia of 1%. " 03/01/2006 - "Three versions of MEDLINE were searched from January 1966 through December 2004 and with a repeated search in August 2005 using 2 groups of search terms: group 1, terms used for hair care and specific study designs: survey, cross-sectional study, and cohort study; group 2, the terms African hair, Afro-Caribbean hair, African American hair, central centrifugal cicatricial alopecia, acne keloidalis nuchae, traction alopecia, and synonyms for each. " 01/01/2015 - "We will also review the most prominent of the ethnic hair conditions including acquired trichorrhexis nodosa, traction alopecia, central centrifugal cicatricial alopecia, pseudofolliculitis barbae, dissecting cellulitis, and acne keloidalis nuchae. " 08/01/2014 - "Acne keloidalis (AK), central centrifugal cicatricial alopecia (CCCA), dissecting cellulitis of the scalp (DCS), pseudofolliculitis barbae (PFB), traction alopecia (TA), and keloids are the most prevalent follicular and scarring disorders in skin of color. "
5.	Transplants (Transplant) 12/01/1951 - "Skin graft in the treatment of chronic furunculosis of the posterior surface of the neck (folliculitis keloidalis)." 01/01/2009 - "Acne keloidalis of the scalp in a renal transplant patient treated with cyclosporine."