An enzyme that catalyzes the conversion of acetate esters and water to alcohols and acetate. EC
Also Known As:
Acetate Esterase; Acid Esterase; Esterase-17; Esterase 17; Esterase, Acetate; Esterase, Acid; Acetylase; Acetic-ester acetylhydrolase
Networked: 97 relevant articles (2 outcomes, 7 trials/studies)

Relationship Network

Bio-Agent Context: Research Results


1. Nitz, Mark: 1 article (06/2015)
2. Pokrovskaya, Varvara: 1 article (06/2015)
3. Howell, P Lynne: 1 article (06/2015)
4. Ariyakumaran, Rishikesh: 1 article (06/2015)
5. Little, Dustin J: 1 article (06/2015)
6. Cai, Mingbo: 1 article (02/2015)
7. Lin, Bei: 1 article (02/2015)
8. Zhu, Liancheng: 1 article (02/2015)
9. Zhang, Danye: 1 article (02/2015)
10. Hou, Rui: 1 article (02/2015)

Related Diseases

1. Lymphoma (Lymphomas)
12/01/1982 - "Analysis of acid esterase activity and polymorphism as an aid for the classification of human low-grade malignant non-Hodgkin's lymphomas."
08/31/1984 - "In the T zone lymphoma the neoplastic lymphocytes were E+ (90%) and exhibited intensive focal staining for acid phosphatase (93%) and acid esterase (92%); the phenotype distribution revealed low expression of the T-3 antigen (49%), selective expression of the T-4 antigen (72%) and poor expression of T-6 (10%) and T-10 antigens (22%). "
01/12/1980 - "As far as T-lymphomas are concerned, three hydrolases namely acid phosphates e, acid esterase and B-glucuronidase give the same good results. "
10/01/1987 - "In 84 leukemic non-Hodgkin-lymphomas the diagnostic evidence of peripheral blood smears in Pappenheim-staining and diverse cytochemical reactions (PAS, alpha-naphthyl acetate esterase, acid phosphatase, acid esterase, beta-glucuronidase) was analysed using a homogeneous cell grid (lymphatic differential blood picture). "
08/01/1984 - "These results were obtained: (1) TdT (90 cases) was highly specific for LL; eight of nine LL were positive, and all other histologic types were negative; the only TdT-, acid esterase (AcE) positive, nonconvoluted LL was probably related to TdT- normal medullary thymocytes, and had an unfavorable clinical course with resistance to a vincristine-and-prednisone-including treatment; (2) ADA (61 cases) could distinguish clearly between the high levels of LL and the low levels found in any other group of lymphomas; among LL, the highest values were found in T-cell-derived neoplasias, and the lowest value in a periodic acid-Schiff (PAS) positive, acid phosphatase negative case that showed the presence of large nucleoli at the ultrastructural analysis, a finding that is unusual for LL and possibly related to a more immature differentiation stage; (3) PNP (39 cases) values alone were not clinically relevant, but together with ADA levels, a subset of T-LL with high ADA:PNP ratio could be selected among LL; (4) DP alpha (61 cases), and TK and UK (37 cases) were found in concentrations reflecting the malignancy of the non-Hodgkin's lymphoma, and were more elevated in the high-grade malignant lymphomas; (5) ThPh (34 cases) was always elevated in Hodgkin's disease, but low in Burkitt's lymphoma and LL; thus, they had a high TK:ThPh ratio that could be useful in predicting clinical response to thymidine treatment. "
2. Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
3. Neoplasms (Cancer)
4. Wolman Disease (Wolman's Disease)
5. Melanoma (Melanoma, Malignant)

Related Drugs and Biologics

1. Glucuronidase
2. Acid Phosphatase
3. Naphthol AS D Esterase (ANAE)
4. Hydrolases
5. Hexosaminidases (Hexosaminidase)
6. Phosphates
7. Histones (Histone)
8. Chloramphenicol (Chloromycetin)
9. 1-naphthol (alpha-naphthol)
10. Protein Kinases (Protein Kinase)

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Ligation