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Acetyl-CoA C-Acetyltransferase (Acetyl Coenzyme A Acetyltransferase)

An enzyme that catalyzes the formation of acetoacetyl-CoA from two molecules of ACETYL COA. Some enzymes called thiolase or thiolase-I have referred to this activity or to the activity of ACETYL-COA C-ACYLTRANSFERASE.
Also Known As:
Acetyl Coenzyme A Acetyltransferase; Acetyl CoA Acetyltransferase; Acetyl CoA C Acetyltransferase; Acetyltransferase, Acetyl-CoA; C-Acetyltransferase, Acetyl-CoA; CoA Thiolase, Acetoacetyl; Thiolase, Acetoacetyl CoA; Acetoacetyl CoA Thiolase; Acetyl-CoA Acetyltransferase; Acetyl-CoA:acetyl-CoA C-acetyltransferase
Networked: 47 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Wan, Wei: 1 article (04/2022)
2. Xu, Yinfeng: 1 article (04/2022)
3. Cai, Shaoxi: 1 article (01/2022)
4. Chen, Liting: 1 article (01/2022)
5. Dupont, Nicolas: 1 article (01/2022)
6. Filali-Mouncef, Yasmina: 1 article (01/2022)
7. Garza, Samuel: 1 article (01/2022)
8. Hunter, Catherine: 1 article (01/2022)
9. Ishida, Yuji: 1 article (01/2022)
10. Lazaris, Anthoula: 1 article (01/2022)

Related Diseases

1. Hypoxia (Hypoxemia)
2. Lymphoma (Lymphomas)
3. Neoplasms (Cancer)
4. Ketosis
5. Infections
06/01/2009 - "A functional enrichment analysis to identify which host pathways were perturbed during each of these infections identified several pathways related to cholesterol biosynthesis, including cholesterol metabolic processes, hydroxymethylglutaryl-coenzyme A (CoA) reductase activity, and acetyl-CoA C-acetyltransferase activity. "
01/01/2023 - "Investigation of the intestinal microbiomés functional composition revealed reduced expression of flagellin and rubrerythrin and increased levels of ATPase during pneumococcal infection, while increased amounts of acetyl coenzyme A (acetyl-CoA) acetyltransferase and enoyl-CoA transferase were unique after H1N1 infection. "
04/01/2018 - "ABC: ATP binding cassette transport; ACADVL: acyl-CoA dehydrogenase, very long chain; ACAT: mitochondrial-like acetyl-CoA acetyltransferase A; ACAT2: acetyl-CoA acyltransferase 2; ACNAT2: acyl-coenzyme A amino acid N-acyltransferase 2-like; ACOT1: acyl-CoA thioesterase 1; ACOT7: acyl-CoA thioesterase 7; ACOX1: acyl-CoA oxidase 1, palmitoyl; ACSBG2: acyl-CoA synthetase bubblegum family member 2; ACSL1: acyl-CoA synthetase long-chain family member 1; ADH1: alcohol dehydrogenase 1; APOA4: apolipoprotein A-IV; ARV: avian reovirus; cDNA: complementary deoxyribonucleic acid; COG: Clusters of Orthologous Groups; DEG: differentially expressed gene; DGAT: diacylgycerol acyltransferase; DNA: deoxyribonucleic acid; ECI2: enoyl-CoA delta isomerase 2; EHHADH: enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase; FDR: false discovery rate; GCDH: Pseudopodoces humilis glutaryl-CoA dehydrogenase; GO: Gene Ontology; HADHA: hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit; I-FABP: intestinal fatty acid binding protein; KEGG: Kyoto Encyclopedia of Genes and Genomes; L-FABP: liver fatty acid binding protein; MDRV: Muscovy duck reovirus; MOI: multiplicity of infection; NPC1L1: Niemann-Pick C1-like 1; qPCR: real-time quantitative polymerase chain reaction; RNA: ribonucleic acid; RNase: ribonuclease; RNA-seq: RNA sequencing technology; RPKM: reads per kilobase per million mapped reads; SR-B1: scavenger receptor class b type 1."

Related Drugs and Biologics

1. Ketones
2. Cholesterol
3. Scavenger Receptors (Scavenger Receptor)
4. Nicorandil (SG 75)
5. Proteins (Proteins, Gene)
6. Coenzyme A (CoA)
7. Transferases
8. Enzymes
9. Oxidoreductases (Dehydrogenase)
10. Acetyl-CoA C-Acyltransferase (beta Ketothiolase)