Septic Abortion

Any type of abortion, induced or spontaneous, that is associated with infection of the UTERUS and its appendages. It is characterized by FEVER, uterine tenderness, and foul discharge.

Also Known As:

Networked: 111 relevant articles (5 outcomes, 3 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Incomplete Abortion
2.	Abscess
3.	Uterine Perforation
4.	Disseminated Intravascular Coagulation
5.	Abruptio Placentae (Placental Abruption)

Experts

1.	Savaris, Ricardo F: 2 articles (11/2013 - 04/2011)
2.	Bonessio, L: 2 articles (10/2001 - 04/2001)
3.	Spina, V: 2 articles (10/2001 - 04/2001)
4.	Aleandri, V: 2 articles (10/2001 - 04/2001)
5.	Bartucca, B: 2 articles (10/2001 - 04/2001)
6.	Bertelli, S: 2 articles (10/2001 - 04/2001)
7.	Mastrolia, Salvatore Andrea: 1 article (10/2015)
8.	Thachil, Jecko: 1 article (10/2015)
9.	Erez, Offer: 1 article (10/2015)
10.	Lessard-Anderson, Collette: 1 article (04/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Septic Abortion:

1.	Anti-Bacterial Agents (Antibiotics)IBA 03/01/1977 - "Aggressive management that included early uterine evacuation and broad-spectrum antibiotics effective against both aerobic and anaerobic bacteria was the key to reduced morbidity and mortality rates in treatment of septic abortion. " 04/01/2011 - "We sought to investigate whether oral antibiotics are necessary, after 48 hours of clinical improvement, in uncomplicated septic abortion. " 04/01/2011 - "Are antibiotics necessary after 48 hours of improvement in infected/septic abortions? " 04/01/2011 - "In a randomized double-blind clinical trial, 56 women with uncomplicated septic abortion were treated with intravenous antibiotics, followed by uterine evacuation. " 06/01/1952 - "[Septic abortion and antibiotics]."
2.	Cefoxitin (Cefoxitin Sodium)FDA LinkGeneric 03/01/1986 - "An uncontrolled clinical trail was carried out to assess the efficacy of cefoxitin as the sole antimicrobial agent in the treatment of 22 cases of septic abortion in Lagos, Nigeria. " 03/01/1986 - " These findings suggest that cefoxitin can be used as a single antimicrobial agent in the treatment of septic abortion and may offer advantages over the use of a combination of antimicrobials." 03/01/1986 - "It appears that cefoxitin was successful as a single agent in the treatment of septic abortion. " 03/01/1986 - "Using strict diagnostic criteria, a clinical trial of cefoxitin as the only antimicrobial agent in the treatment of twenty-five cases of septic abortion was carried out. " 03/01/1986 - "Cefoxitin: single agent treatment of septic abortion."
3.	Fibrinogen (Factor I)FDA Link 10/01/1992 - "We present a study of fibrinogen levels in 133 patients who were prone to develop disseminated intravascular coagulation as a result of an underlying complication of pregnancy such as abruptio placentae, pregnancy-induced hypertension, missed abortion, septic abortion, intrauterine fetal death, vesicular mole and amniotic fluid embolism. "
4.	Heparin (Liquaemin)FDA LinkGeneric 01/01/1980 - "While in obstetrics heparin treatment of coagulopathy, generally, has been abandoned-prophylactic use of heparin has worked well, particularly in cases of septic abortion. " 01/01/1980 - "[Use of heparin in cases of septic abortion (author's transl)]." 01/01/1978 - "The generally accepted value of prophylactic medication of heparin in cases of septic abortion is not diminished by these casuistic observations. " 01/01/1978 - "Report on 62 cases of septic abortion with prophylactic use of heparin. " 01/01/1978 - "[Experiences with the preventive use of heparin in septic abortion]."
5.	Dacarbazine (DIC)FDA LinkGeneric 12/01/2001 - "This scenario of coagulation activation probably describes the principal events underlying emerging acute DIC states under pathophysiological conditions such as abruptio placentae, septic abortion, amniotic fluid embolization, and pregnancy toxemia. " 10/01/2001 - "Nevertheless, severe complications are possible in the case of septic abortion, including septicaemia, septic shock, DIC, renal insufficiency. " 02/01/2008 - "Clinical spectrum of pregnancy related ARF showed APH in 6 (14%) cases, PPH in 9 (24%) cases, septic abortion and puerperal sepsis and DIC in 13 (31%) cases, IUD in 6 (14%) and preeclampsia / eclampsia in 5 (12%) cases. " 10/01/2009 - "Postpartum haemorrhage was present in 14 (23.33%), postpartum haemorrhage and disseminated intravascular coagulation (DIC) in 11 (18.33%), eclampsia-preeclampsia in 8 (13.33%), antepartum haemorrhage in 8 (13.33%), antepartum haemorrhage with DIC in 6 (10%), DIC alone in 4 (6.66%), obstructed labour in 3 (5%), septic abortion in 3 (3.33%), HELLP (haemolysis elevated liver enzyme and low platelet) in 2 (3.33%), urinary tract infection with sepsis in 1 (1.66%) and puerperal sepsis in 1 (1.66%). " 02/01/1995 - " About 33% of septic abortion cases presented with generalized peritonitis, septicemia, septic shock, acute renal failure, or disseminated intravascular coagulation (DIC). "
6.	Clindamycin (Cleocin)FDA LinkGeneric 01/01/1991 - "Clindamycin (alone or with an aminoglycoside) has been used successfully in posthysterectomy vaginal cuff infections and, with an aminoglycoside, in septic abortions. " 11/01/2013 - "To compare the rates of cure of septic abortion and pelvic inflammatory disease using a daily dose of clindamycin with gentamicin versus divided doses, we conducted a retrospective cohort study, where the electronic records of 661 patients who used clindamycin 1 × , 3 × or 4 ×/day (groups 1, 3 and 4, respectively) between September 2002 and August 2010 were analysed. " 03/01/1977 - "The responses to therapy with either clindamycin alone or penicillin plus chloramphenicol in 77 patients with septic abortions were compared in a randomized, double-blind study. " 03/01/1977 - "A double-blind comparison of clindamycin with penicillin plus chloramphenicol in treatment of septic abortion." 08/01/1986 - "The efficacy and safety of piperacillin were compared with those of clindamycin plus gentamicin in 74 women with obstetric or gynecologic infections (such as endometritis, salpingitis and septic abortion). "
7.	CopperIBA 02/25/1978 - "Mid-trimester septic abortion and Escherichia coli septicaemia in a copper IUCD user." 07/01/1993 - "Equating the performance of the Dalkon Shield IUD to that of the Lippes Loop or of Copper IUDs is erroneous, however, with respect to rates of pregnancy, expulsion, pelvic infection, septic abortion, death with the device in situ, and tubal infertility. " 10/01/1982 - " The Dalkon Shield has been associated with midtrimester septic abortions and with unilateral actinomycotic tube-ovarian abscesses and there is evidence to support a chemically caused IUD-related endometritis in the moderate inflammation associated with IUDs containing copper and with the Majzlin spring. "
8.	Soaps (Soap)IBA 05/30/1966 - "[A case of meningoencephalitis purulenta after soap septic abortion]." 04/03/1975 - "20 cases of septic abortion were reviewed, all of which had suffered septic shock and renal failure attributed to intrauterine instillation of soap or phenolic antiseptic solutions, which were treated at Hammersmith Hospital from 1965-1972 to determine proper management of such patients. " 04/03/1975 - "The concept that hysterectomy is of value in the management of septic abortion induced by instillation of soap or phenolic antiseptics into the uterus is challenged. "
9.	Rifampin (Rifampicin)FDA LinkGeneric 12/01/1972 - "[Evaluation of rifampicin in septic abortion]." 01/01/1971 - "[Treatment of septic abortion with rifampicin]."
10.	Oxytetracycline (Terramycin)FDA Link 03/01/1966 - "[Treatment of septic abortion with early surgery and intravenous oxytetracycline]." 06/13/1965 - "[Intravenous use of oxytetracycline in septic abortions]."

Therapies and Procedures

1.	Vacuum Curettage (Vacuum Pump) 07/01/1998 - "The Department of Obstetrics and Gynaecology, College of Medicine, University of Lagos commenced training programmes in the use of manual Vacuum Aspiration (MVA) for the treatment of septic abortion in 1989. " 10/01/1971 - "Vacuum curettage in septic abortion." 11/01/1990 - "In a study to assess the efficacy of and safety of vacuum aspiration syringe in the management of incomplete abortion 300 patients with non septic abortion were evacuated by the method in the ward. "
2.	Contraception (Birth Control) 02/01/1995 - " No septic abortion case had used contraception. " 08/04/1994 - " Primary prevention of septic abortion encompasses the provision of effective contraception, provision of safe and legal abortion in cases of contraceptive failure, and appropriate medical management of abortion. " 01/01/2004 - "Although they are termed to be a safe and effective method for contraception, they also have some type of complications and uterine perforation, septic abortion, pelvic abscess are the serious complications of these devices. " 04/01/1988 - "These include better antenatal and intrapartum care, contraception for women who want no more pregnancies, legal abortion to terminate unwanted pregnancies, and uterine aspiration and antibiotics for treatment of septic abortion. "
3.	Hysterectomy 02/01/1979 - " The author cites 3 clinical studies, including a total abdominal hysterectomy, a septic abortion, and an IUD perforation, which responded to this treatment." 04/01/2015 - "Initiation of a second-trimester termination procedure with lethal fetal injection resulted in subsequent septic abortion necessitating abdominal hysterectomy. " 01/01/2009 - "Hysterectomy may represent a beneficial therapeutic solution for septic abortion, nevertheless with irreversible effects on a woman's reproductive condition. " 03/01/2001 - "Complication of pregnancy still accounted for a high percentage of hysterectomy (11%) Most were ante-partum and post partum haemorrhages as well as septic abortion in young women Ten of the specimens were normal both grossly and microscopically. " 09/17/1988 - "It is concluded that ovaries which appear normal at hysterectomy for septic abortion should be conserved."
4.	Induced Abortion (Induced Abortions) 05/01/2012 - "Determine the clinical indications of illegal induced abortion, comparison between septic and non-septic abortion. " 05/01/2012 - "Comparison of condition specific indicators among illegal induced abortion: septic and non-septic abortion in Songkla Center Hospital." 01/01/2009 - "Septic abortion represents the main causes of abortion-induced maternal death. " 10/01/2005 - "Increasing public awareness about hazards of septic abortion and the provisions of law and decentralizing the trained manpower throughout the country would play a pivotal role in decreasing the incidence of septic induced abortion." 04/01/2001 - "Eighteen patients (43%) were nulliparous; 24 (57%) multiparous; 14 (33%) had previous abortions, none had previous septic abortions. "
5.	Renal Dialysis (Hemodialysis) 01/01/2011 - "The patient was treated as septic abortion and reached partial renal recovery after antibiotic treatment and short-term hemodialysis. " 08/01/1978 - "[Hemodialysis in the treatment of acute renal insufficiency in septic abortions]." 08/01/1974 - "[Hemodialysis in the treatment of acute renal insufficiency complicating the puerperal and post-abortion septic diseases]." 06/01/1967 - "[Changes in acid-base equilibrium during hemodialysis in patients with acute renal insufficiency arising as a result of septic abortion]." 01/01/1964 - "[ACUTE RENAL INSUFFICIENCY IN SEPTIC ABORTION AND DELIVERY AND ITS TREATMENT USING EXTRACORPOREAL HEMODIALYSIS (ARTIFICIAL KIDNEY)]."