HOME PRODUCTS SERVICES COMPANY CONTACT FAQ

Missed Abortion

Subscribe to New Research on Missed Abortion

The retention in the UTERUS of a dead FETUS two months or more after its DEATH.

Also Known As:

Abortion, Missed; Abortions, Missed; Missed Abortions

Networked: 284 relevant articles (16 outcomes, 26 trials/studies)

Relationship Network

Disease Context: Research Results

Female Urogenital Diseases and Pregnancy Complications
- Pregnancy Complications: 986
  - Spontaneous Abortion: 4857
    - Missed Abortion: 284

Related Diseases

1.	Fetal Death
2.	Spontaneous Abortion (Miscarriage)
3.	Missed Abortion
4.	Ectopic Pregnancy
5.	Incomplete Abortion

Experts

1.	Daponte, Alexandros: 5 articles (01/2013 - 09/2011)
2.	Pournaras, Spyros: 5 articles (01/2013 - 09/2011)
3.	Messinis, Ioannis E: 5 articles (01/2013 - 09/2011)
4.	Anastasiadou, Foteini: 3 articles (01/2013 - 09/2011)
5.	Hadjichristodoulou, Christos: 3 articles (01/2013 - 01/2013)
6.	Deligeoroglou, Efthimios: 3 articles (01/2013 - 01/2013)
7.	Garas, Antonios: 3 articles (01/2013 - 01/2013)
8.	Lathi, Ruth B: 3 articles (05/2010 - 11/2002)
9.	Milki, Amin A: 3 articles (05/2010 - 11/2002)
10.	Winikoff, B: 3 articles (12/2007 - 01/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Missed Abortion:

1.	Misoprostol (Cytotec)FDA LinkGeneric 11/01/2002 - "Vaginal misoprostol 0.4-0.6 mg is effective in most patients with missed abortion. " 10/01/2000 - "The described regimen of vaginal misoprostol is safe and reasonably effective in inducing complete evacuation in missed abortions. " 10/01/2000 - "To evaluate the efficacy of a regimen of vaginal misoprostol in causing the complete expulsion of first-trimester missed abortions, or alternatively dilating the cervix for surgical evacuation. " 08/01/2005 - "We conclude that misoprostol is effective in the management of missed abortion in the second trimester in Nigeria." 09/01/1998 - "Vaginal misoprostol alone is effective in the treatment of missed abortion."
2.	Dinoprostone (PGE2)FDA Link 01/01/2008 - "To compare the efficacy of two routes of prostaglandin E2 administration (Intravenous and Intramuscular) for treatment of missed abortion this study was conducted. " 09/01/1978 - "The efficacy of prostaglandin E2 (PGE2) for the induction of labor in pregnancies complicated by IUFD or missed abortion has been demonstrated. " 01/01/2008 - "Regarding the pilot cases of missed abortion admitted for termination of pregnancy intravenous administration of PGE2 that had higher efficacy compare to intramuscular route, investigators designed this study. " 01/01/2008 - "Comparison between Intravenous and Intramuscular Administration of Prostaglandin E2 on Management of Missed Abortion." 01/01/1980 - "To terminate pregnancy 15 women with an established diagnosis of missed abortion or intrauterine dead fetuses were treated with 1.0 mg Prostaglandin E2 in viscous gel applied as a single intracervical dose. "
3.	Mifepristone (RU 486)FDA Link 08/28/1993 - "Of the 1151 women with known outcome, 95.5% had a complete abortion (364 (93.8%) of those given 200 mg mifepristone, 368 (94.1%) of those given 400 mg, and 367 (94.3%) of those given 600 mg), 3.7% had an incomplete abortion (14 (3.6%), 15 (3.8%), and 14 (3.6%)), 0.3% had a missed abortion (three (0.8%), one (0.3%), and none), and 0.4% had a continuing live pregnancy (two (0.5%), two (0.5%), and one (0.3%)). " 11/01/2002 - "To compare the efficacy of two different medical treatment regimens: mifepristone 600 mg orally + misoprostol 0.4 mg vaginally (Mf + Ms) or misoprostol 0.4 mg vaginally (Ms) with conventional surgical evacuation (SE) in women with missed abortion. " 04/06/1994 - "In a 1992 study, 60 patients with pregnancy up to the 13th week were treated with 600 mg of mifepristone and 36-48 hours later with 600 mcg of misoprostol (Cytotec) for missed abortion and anembryonic pregnancy. " 11/01/2002 - "Management of missed abortion: comparison of medical treatment with either mifepristone + misoprostol or misoprostol alone with surgical evacuation. " 03/01/2002 - "Mifepristone and misoprostol prescribed to 100 women with an ultrasonically confirmed missed abortion was compared with 100 women who had surgical evacuation under general anaesthesia for their missed abortion. "
4.	DinoprostIBA 01/01/1986 - "Prostaglandin (F2 alpha) in missed abortion. " 04/01/1985 - "[Transcervical intra-amniotic induction with PgF2 alpha in missed abortion and labor in the 3d trimester of pregnancy with dead fetus. " 07/01/1983 - "A combined method consisting of extraamniotic infusion of normal saline with prostaglandin F2 alpha was used in 20 patients for termination of midtrimester missed abortion. " 07/01/1983 - "Extraamniotic infusion of prostaglandin F2 alpha in normal saline for termination of midtrimester missed abortion." 12/01/1982 - " 15(S) 15 methyl PGF2alpha has a high degree of efficacy in the management of missed abortion."
5.	Oxytocin (Pitocin)FDA LinkGeneric 02/01/1981 - " Only 1.57% of women with regular pregnancy did not need oxytocin, versus 31.8% of women with missed abortion. " 06/01/1976 - "After a preliminary report on 20 cases, we have used extra-amniotic perfusion of isotonic saline, in association or not with syntocinon, for performing:--56 2nd trimester therapeutic abortions,--16 labor inductions in interrupted 2nd and 3rd trimester pregnancies, with macerated fetus (missed abortion and missed labor). " 08/15/1966 - "Management of missed abortion by highly concentrated intravenous oxytocin." 01/01/1963 - "[TREATMENT OF MISSED ABORTION BY CONTINUOUS PERFUSION OF WEAK DOSES SYNTOCINON]." 11/28/1962 - "THE USE OF HIGH CONCENTRATION PITOCIN INTRAVENOUS DRIPS IN THE MANAGEMENT OF MISSED ABORTION."
6.	Nitric Oxide (Nitrogen Monoxide)FDA Link 12/01/2005 - "To determine the therapeutic efficacy and safety of a nitric oxide (NO) isosorbide dinitrate donor to induce cervical ripening of women with missed abortions before surgical evacuation of the uterus. "
7.	Isosorbide Dinitrate (Isordil)FDA LinkGeneric 12/01/2005 - "Intracervical administration of 80 mg isosorbide dinitrate in women with missed abortions appears to be effective for cervical ripening prior to surgical evacuation of the uterus. " 12/01/2005 - "To determine the therapeutic efficacy and safety of a nitric oxide (NO) isosorbide dinitrate donor to induce cervical ripening of women with missed abortions before surgical evacuation of the uterus. "
8.	Dihydrotachysterol (AT 10)IBA 02/01/1998 - " The present study investigated the availability and effectiveness of such follow-up care in 204 women (median age, 36 years) from London, England, who received a diagnosis of missed abortion or anembryonic pregnancy at 10-14 weeks of gestation in 1995-96. " 07/01/1997 - "In an ultrasound screening study at 10 to 14 weeks of gestation involving 492 twin pregnancies the prevalence of missed abortion was about twice as high as in singletons. " 03/01/1996 - "In an ultrasound screening study at 10-13 weeks of gestation involving 17,870 women, the prevalence of early pregnancy failure was 2.8% (501 cases), including 313 (62.5%) missed abortions and 188 (37.5%) anembryonic pregnancies. " 04/01/2015 - "Decidual materials were collected from patients diagnosed with a missed abortion (n = 10) (missed abortion group) and from legal voluntary termination cases at < 10 gestational weeks (n = 10) (normal pregnancy group). " 07/01/1997 - "In singleton pregnancies at 10 to 14 weeks of gestation the prevalence of missed abortion is about 2%. "
9.	Fibrinogen (Factor I)FDA Link 01/01/2011 - "In addition, fibrinogen was decreased in the missed abortion group. " 10/01/1965 - "[Drop of the fibrinogen level in missed abortion]." 10/01/1992 - "We present a study of fibrinogen levels in 133 patients who were prone to develop disseminated intravascular coagulation as a result of an underlying complication of pregnancy such as abruptio placentae, pregnancy-induced hypertension, missed abortion, septic abortion, intrauterine fetal death, vesicular mole and amniotic fluid embolism. " 01/01/2011 - "Troponin I, C-reactive protein and fibrinogen levels in missed abortions." 01/01/2011 - "The aim of the study was to evaluate serum concentrations of troponin I, C-reactive protein (CRP), fibrinogen and ferritin levels in women with missed abortion and normal pregnancy. "
10.	Suppositories (Vaginal Suppositories)IBA 05/01/1987 - "Forty-eight patients affected with missed abortion, intrauterine fetal death and hydatiform mole were treated with vaginal suppositories containing 1 mg of 16,16-dimethyl-trans-delta 2-PGE1 methyl ester (ONO-802). " 03/15/1977 - "Induction of labor in patients with missed abortion and fetal death in utero with protaglandin E2 suppositories." 01/01/1983 - "In the present study 68 consecutive patients with a missed abortion or hydatiform mole were treated with vaginal suppositories containing either 15-methyl-PGF2 alpha methyl ester or 9-deoxo-16,16-dimethyl-9-methylene PGE2. " 08/01/1980 - "The availability of the vaginal PGE2 suppositories for missed abortion and IUFD makes it important for the clinician to fully acquaint himself with the drug, its administration, effects, and side effects." 05/01/1976 - "Management of intrauterine fetal demise and missed abortion using prostaglandin E2 vaginal suppositories."

Therapies and Procedures

1.	Curettage 04/01/2012 - "Comparative histological study of uterine curettage specimens in missed abortion in women with spontaneous and induced pregnancy and progressing spontaneous pregnancy revealed similar changes in the endometrium and placental villi. " 03/01/2015 - "The most common etiologies for intrauterine adhesions were previous curettage (60%) and previous missed abortion (45%). " 03/01/2013 - "Only uterine curettage was done once for missed abortion. " 05/01/2011 - "Initially the curettage of the missed abortion damaged the endometrial lining. " 05/01/2011 - "She had undergone curettage of missed abortion two months previously and the aborted material showed normal placental tissue on histopathologic examination. "
2.	Oral Administration 11/01/2004 - "To compare the efficacy of two routes of misoprostol administration (oral and vaginal) for treatment of missed abortion. " 01/01/2006 - "We aimed to investigate the effectiveness and adverse effects of combined (vaginal + oral) administration of misoprostol in missed abortion cases. "
3.	Sublingual Administration 06/01/2010 - "To evaluate the efficacy of two routes of misoprostol administration (sublingual and vaginal) for the treatment of missed abortion. "
4.	Dilatation and Curettage (D&C) 11/01/2014 - "Ultrasound assessment confirmed a missed abortion, and the patient underwent dilatation and curettage. " 01/01/2014 - "D&C was performed for missed abortion at 9 weeks. " 01/01/2013 - "Pyomyoma after dilatation and curettage for missed abortion." 05/01/2011 - "She underwent D&C for missed abortion at 8 weeks' gestation. " 01/01/2011 - "A hysteroscopy was performed in 100 women four to 12 weeks after a dilatation and curettage for missed abortions. "
5.	Induced Abortion (Induced Abortions) 01/01/2014 - "As soon as the diagnosis of "missed abortion" was definitively made, the chorionic trophoblast was obtained by induced abortion operation. " 01/01/2013 - "Both in induced abortion and missed abortion, Dll4 was positively correlated with Notch1. " 08/01/1994 - "Mean operative time (minutes) for induced abortion was statistically similar in the unscarred compared with the scarred uteri groups (8.03 +/- 4.40 vs 7.46 +/- 4.42, respectively) and was statistically different when the indication for evacuation was missed abortion (6.08 +/- 1.86 vs 4.81 +/- 2.11, respectively; p < 0.005). " 11/01/2010 - "Of the 914 abortions, 751 (82.25) were induced abortions, 146 (16.0%) were spontaneous abortions, 9 (0.98%) were missed abortions, and 8 were unclassified. " 03/01/2000 - "We studied 2,602 deaths, 15% of which were due to missed abortion, spontaneous abortion, or legally permitted induced abortion. "