Drug-Induced Abnormalities (Abnormalities, Drug Induced)

Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.

Also Known As:

Networked: 11 relevant articles (0 outcomes, 1 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Cognitive Dysfunction
2.	Neurodegenerative Diseases (Neurodegenerative Disease)
3.	Hyperpigmentation
4.	Spinal Dysraphism (Spina Bifida)
5.	Ulcer

Experts

1.	Buratta, Sandra: 1 article (11/2021)
2.	Delo, Federica: 1 article (11/2021)
3.	Emiliani, Carla: 1 article (11/2021)
4.	Giovagnoli, Stefano: 1 article (11/2021)
5.	Pellegrino, Roberto Maria: 1 article (11/2021)
6.	Sagini, Krizia: 1 article (11/2021)
7.	Urbanelli, Lorena: 1 article (11/2021)
8.	Cabanillas, Miguel: 1 article (04/2018)
9.	González-Vilas, Daniel: 1 article (04/2018)
10.	Iriarte, Pilar: 1 article (04/2018)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Drug-Induced Abnormalities:

1.	Valproic Acid (Depakote)FDA LinkGeneric 01/01/2010 - "The aim of this study was to assess the potentially drug-induced abnormalities in the SEP parameters in epileptic children, treated chronically in monotherapy with one of the two most often used antiepileptic drugs: valproate (VPA) or carbamazepine (CBZ). " 07/01/1998 - "Search terms included phenytoin, carbamazepine, phenobarbital, primidone, valproic acid, oral contraceptives, clomiphene, drug-induced abnormalities, spina bifida, anencephaly, neural tube defect, folate, folic acid, and folic acid deficiency. "
2.	Carbamazepine (Tegretol)FDA LinkGeneric 01/01/2010 - "The aim of this study was to assess the potentially drug-induced abnormalities in the SEP parameters in epileptic children, treated chronically in monotherapy with one of the two most often used antiepileptic drugs: valproate (VPA) or carbamazepine (CBZ). " 07/01/1998 - "Search terms included phenytoin, carbamazepine, phenobarbital, primidone, valproic acid, oral contraceptives, clomiphene, drug-induced abnormalities, spina bifida, anencephaly, neural tube defect, folate, folic acid, and folic acid deficiency. "
3.	Anticonvulsants (Antiepileptic Drugs)IBA 01/01/2010 - "The aim of this study was to assess the potentially drug-induced abnormalities in the SEP parameters in epileptic children, treated chronically in monotherapy with one of the two most often used antiepileptic drugs: valproate (VPA) or carbamazepine (CBZ). "
4.	Phenytoin (Dilantin)FDA LinkGeneric 08/01/1976 - "Diphenylhydantoin (dilantin) gingival hyperplasia: drug-induced abnormality of connective tissue." 07/01/1998 - "Search terms included phenytoin, carbamazepine, phenobarbital, primidone, valproic acid, oral contraceptives, clomiphene, drug-induced abnormalities, spina bifida, anencephaly, neural tube defect, folate, folic acid, and folic acid deficiency. "
5.	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 11/10/2023 - "CTD Analysis showed that the 4 core genes (Fgf2, Pdgfra, Ptpn11, Slc2a1) were associated with neurodegenerative diseases, brain injuries, memory disorders, cognitive disorders, neurotoxicity, drug-induced abnormalities, neurological disorders, developmental disorders, and intellectual disabilities. "
6.	Biomarkers (Surrogate Marker)IBA 05/01/2017 - "Recently, numerous models and techniques have been developed for analyzing and extracting features from the T wave which could be used as biomarkers for drug-induced abnormalities. "
7.	TeratogensIBA 01/12/1994 - "The search terms were lithium, pregnancy, teratogen, abnormalities (drug induced), Ebstein's anomaly, and adverse effects. "
8.	Prostaglandins EIBA 11/01/1980 - "The apparently normal stimulation of PGA and PGE in subjects with diabetic HH suggests that this syndrome is not associated with abnormal prostaglandin metabolism, despite the fact that drug-induced abnormalities of the latter may precipitate or aggravate the clinical syndrome in susceptible individuals. "
9.	Prostaglandins AIBA 11/01/1980 - "The apparently normal stimulation of PGA and PGE in subjects with diabetic HH suggests that this syndrome is not associated with abnormal prostaglandin metabolism, despite the fact that drug-induced abnormalities of the latter may precipitate or aggravate the clinical syndrome in susceptible individuals. "
10.	ProstaglandinsIBA 11/01/1980 - "The apparently normal stimulation of PGA and PGE in subjects with diabetic HH suggests that this syndrome is not associated with abnormal prostaglandin metabolism, despite the fact that drug-induced abnormalities of the latter may precipitate or aggravate the clinical syndrome in susceptible individuals. "