Drug-Induced Abnormalities (Abnormalities, Drug Induced)

Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.

Also Known As:

Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Spinal Dysraphism (Spina Bifida)
2.	Neural Tube Defects (Exencephaly)
3.	Folic Acid Deficiency (Folic Acid Deficiencies)
4.	Ebstein Anomaly (Ebsteins Anomaly)
5.	Anencephaly (Aprosencephaly)

Experts

1.	Gates, Jonathan D: 1 article (02/2015)
2.	Gormley, William B: 1 article (02/2015)
3.	Havens, Joaquim M: 1 article (02/2015)
4.	Kaufman, Richard M: 1 article (02/2015)
5.	Briggs, Alexandra: 1 article (02/2015)
6.	Calahan, Christopher: 1 article (02/2015)
7.	Kułak, W: 1 article (01/2010)
8.	Sobaniec, W: 1 article (01/2010)
9.	Smigielska-Kuzia, J: 1 article (01/2010)
10.	Sendrowski, K: 1 article (01/2010)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Drug-Induced Abnormalities:

1.	Valproic Acid (Valproate, Semisodium)FDA LinkGeneric 01/01/2010 - "The aim of this study was to assess the potentially drug-induced abnormalities in the SEP parameters in epileptic children, treated chronically in monotherapy with one of the two most often used antiepileptic drugs: valproate (VPA) or carbamazepine (CBZ). " 07/01/1998 - "Search terms included phenytoin, carbamazepine, phenobarbital, primidone, valproic acid, oral contraceptives, clomiphene, drug-induced abnormalities, spina bifida, anencephaly, neural tube defect, folate, folic acid, and folic acid deficiency. "
2.	Carbamazepine (Tegretol)FDA LinkGeneric 01/01/2010 - "The aim of this study was to assess the potentially drug-induced abnormalities in the SEP parameters in epileptic children, treated chronically in monotherapy with one of the two most often used antiepileptic drugs: valproate (VPA) or carbamazepine (CBZ). " 07/01/1998 - "Search terms included phenytoin, carbamazepine, phenobarbital, primidone, valproic acid, oral contraceptives, clomiphene, drug-induced abnormalities, spina bifida, anencephaly, neural tube defect, folate, folic acid, and folic acid deficiency. "
3.	Anticonvulsants (Antiepileptic Drugs)IBA 01/01/2010 - "The aim of this study was to assess the potentially drug-induced abnormalities in the SEP parameters in epileptic children, treated chronically in monotherapy with one of the two most often used antiepileptic drugs: valproate (VPA) or carbamazepine (CBZ). "
4.	Prostaglandins E (PGE)IBA 11/01/1980 - "The apparently normal stimulation of PGA and PGE in subjects with diabetic HH suggests that this syndrome is not associated with abnormal prostaglandin metabolism, despite the fact that drug-induced abnormalities of the latter may precipitate or aggravate the clinical syndrome in susceptible individuals. "
5.	Prostaglandins A (PGA)IBA 11/01/1980 - "The apparently normal stimulation of PGA and PGE in subjects with diabetic HH suggests that this syndrome is not associated with abnormal prostaglandin metabolism, despite the fact that drug-induced abnormalities of the latter may precipitate or aggravate the clinical syndrome in susceptible individuals. "
6.	Primidone (Sertan)FDA LinkGeneric 07/01/1998 - "Search terms included phenytoin, carbamazepine, phenobarbital, primidone, valproic acid, oral contraceptives, clomiphene, drug-induced abnormalities, spina bifida, anencephaly, neural tube defect, folate, folic acid, and folic acid deficiency. "
7.	PotassiumIBA 07/01/2008 - "Drug-induced abnormalities of potassium metabolism."
8.	Phenytoin (Dilantin)FDA LinkGeneric 07/01/1998 - "Search terms included phenytoin, carbamazepine, phenobarbital, primidone, valproic acid, oral contraceptives, clomiphene, drug-induced abnormalities, spina bifida, anencephaly, neural tube defect, folate, folic acid, and folic acid deficiency. "
9.	Phenobarbital (Luminal)FDA Link 07/01/1998 - "Search terms included phenytoin, carbamazepine, phenobarbital, primidone, valproic acid, oral contraceptives, clomiphene, drug-induced abnormalities, spina bifida, anencephaly, neural tube defect, folate, folic acid, and folic acid deficiency. "
10.	LithiumIBA 01/12/1994 - "The search terms were lithium, pregnancy, teratogen, abnormalities (drug induced), Ebstein's anomaly, and adverse effects. "