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4,2'- difluoro- 5'- (8- fluoro- 7- (1- hydroxy- 1- methylethyl)imidazo(1,2- a)pyridin- 3- yl)biphenyl- 2- carbonitrile

GABAA receptor alpha3-subunit selective agonist

Also Known As:

TP003

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Imidazoles: 150
      - 4,2'-difluoro-5'-(8-fluoro-7-(1-hydroxy-1-methylethyl)imidazo(1,2-a)pyridin-3-yl)biphenyl-2-carbonitrile: 2
  - Pyridines: 88
    - 4,2'-difluoro-5'-(8-fluoro-7-(1-hydroxy-1-methylethyl)imidazo(1,2-a)pyridin-3-yl)biphenyl-2-carbonitrile: 2

Experts

1.	Evenden, John: 1 article (05/2009)
2.	Jonak, Gerald: 1 article (05/2009)
3.	Ross, Laurie: 1 article (05/2009)
4.	Zhou, Jin: 1 article (05/2009)
5.	Atack, John R: 1 article (06/2007)
6.	Bull, Sharlene: 1 article (06/2007)
7.	Dawson, Gerard R: 1 article (06/2007)
8.	Fradley, Rosa L: 1 article (06/2007)
9.	Garrett, Elizabeth M: 1 article (06/2007)
10.	Goodacre, Simon C: 1 article (06/2007)

Related Diseases

1.	Shock 05/01/2009 - "The benzodiazepine, chlordiazepoxide, and two novel subtype-selective gamma-aminobutyric acid-A agonists, TP003 and TPA023, significantly increased response rates mildly suppressed by intermediate levels of electric shock without any effect on unpunished response rate. "
2.	Seizures (Absence Seizure) 06/01/2007 - "Furthermore, the anticonvulsant properties of diazepam, the alpha1- and alpha3-selective compounds zolpidem and TP003, respectively, and the alpha2/alpha3 preferring compound TP13 were studied against PTZ-induced seizures. "

Related Drugs and Biologics

1.	gamma-Aminobutyric Acid (GABA)
2.	Diazepam (Valium)
3.	Chlordiazepoxide (Elenium)
4.	Benzodiazepines
5.	Anticonvulsants (Antiepileptic Drugs)
6.	Zolpidem (Ambien)
7.	7- (1,1- dimethylethyl)- 6- (2- ethyl- 2H- 1,2,4- triazol- 3- ylmethoxy)- 3- (2- fluorophenyl)- 1,2,4- triazolo(4,3- b)pyridazine