13-methoxyisorolandrolide
from Rolandra fruticosa; structure in first source
Networked: 1
relevant articles (0 outcomes,
0 trials/studies)
Bio-Agent Context: Research Results
Experts
1. | Chai, Hee-Byung:
1 article
(04/2010)
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2. | Farnsworth, Norman R:
1 article
(04/2010)
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3. | Kardono, Leonardus B S:
1 article
(04/2010)
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4. | Kinghorn, A Douglas:
1 article
(04/2010)
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5. | Lantvit, Daniel D:
1 article
(04/2010)
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6. | Pan, Li:
1 article
(04/2010)
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7. | Riswan, Soedarsono:
1 article
(04/2010)
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8. | Soejarto, Djaja Doel:
1 article
(04/2010)
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9. | Swanson, Steven M:
1 article
(04/2010)
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10. | de Blanco, Esperanza J Carcache:
1 article
(04/2010)
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Related Diseases
1. | Colonic Neoplasms (Colon Cancer)
04/01/2010
- " Cytotoxicity-guided fractionation of a methanol extract of the leaves and twigs of Rolandra fruticosa using the HT-29 human colon cancer cell line led to the isolation of seven sesquiterpene lactones, including the hitherto unknown isorolandrolide, 13-methoxyisorolandrolide (1), and bourbonenolide, 2alpha,13-diacetoxy-4alpha-hydroxy-8alpha-isobutyroyloxybourbonen-12,6alpha-olide (2), as well as five known compounds, 13-acetoxyrolandrolide (3), 8-desacyl-13-acetoxyrolandrolide-8-O-tiglate (4), 2-epi-glaucolide E (5), 2alpha,13-diacetoxy-4alpha-hydroxy-8alpha-methacryloyloxybourbonen-12,6alpha-olide (6), and 2alpha,13-diacetoxy-4alpha-hydroxy-8alpha-tigloyloxybourbonen-12,6alpha-olide (7). "
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