3- (2- chlorobenzyl)- 1,7- dimethyl- 1H- imidazo(2,1- f)purine- 2,4(3H,8H)- dione

reduces TGF-beta stimulated report activity; putative drug for treating fibrotic conditions; structure in first source

Also Known As:

IM 412; IM-412; IM412 cpd

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

1.	Neoplasms (Cancer) 11/01/2015 - "Thus, IM-412 could serve as a novel therapeutic agent for malignant cancers. " 11/01/2015 - "Collectively, our findings suggest that the synthetic compound IM-412 suppressed the EMT process in MDA-MB-231 cells and thereby effectively inhibited the migration and invasion of these cancer cells. "
2.	Breast Neoplasms (Breast Cancer) 11/01/2015 - "IM-412 inhibits the invasion of human breast carcinoma cells by blocking FGFR-mediated signaling."