cumaside

a complex of monosulfated triterpene glycosides from the sea cucumber Cucumaria japonica and cholesterol with antitumor and immunomodulatory activities; structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Agafonova, I G: 1 article (06/2010)
2.	Aminin, D L: 1 article (06/2010)
3.	Avilov, S A: 1 article (06/2010)
4.	Chaykina, E L: 1 article (06/2010)
5.	Kalinin, V I: 1 article (06/2010)
6.	Stonik, V A: 1 article (06/2010)

Related Diseases

1.	Neoplasms (Cancer) 06/01/2010 - "The highest effect occurs at a treatment once a day for 7 days before the tumor inoculation followed by Cumaside treatment once a day for 7 days. " 06/01/2010 - "Prophylactic treatment with Cumaside and subsequent therapeutic application of 5-fluorouracil suppressed the tumor growth by 43%."
2.	Carcinoma (Carcinomatosis) 06/01/2010 - "Nevertheless Cumaside has an antitumor activity against different forms of experimental mouse Ehrlich carcinoma in vivo both independently and in combination with cytostatics. " 06/01/2010 - "A new immunomodulatory lead Cumaside that is a complex of monosulfated triterpene glycosides from the sea cucumber Cucumaria japonica and cholesterol possesses significantly less cytotoxic activity against sea urchin embryos and Ehrlich carcinoma cells than the corresponding glycosides. "

Related Drugs and Biologics

1.	Cytostatic Agents
2.	Triterpenes
3.	Glycosides
4.	Fluorouracil (Carac)
5.	Cholesterol