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AD4 015

an antineoplastic agent; structure in first source

Also Known As:

AD4-015

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Anthracenes: 12
        Anthrones: 12
        Anthraquinones: 788
        AD4 015: 1
- Quinones: 434
  - Anthraquinones: 788
    - AD4 015: 1
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Anthracenes: 12
    - Anthrones: 12
      - Anthraquinones: 788
        AD4 015: 1

Experts

1.	Annabi, Borhane: 1 article (05/2010)
2.	Das, Abhirup: 1 article (05/2010)
3.	Khosla, Chaitan: 1 article (05/2010)
4.	Lord-Dufour, Simon: 1 article (05/2010)
5.	Roy, René: 1 article (05/2010)
6.	Tahanian, Elizabeth: 1 article (05/2010)

Related Diseases

1.

Neoplasms (Cancer)

05/01/2010 - "In the present study, we evaluated the in vitro antiangiogenic impact of AD4-015 on human brain microvascular endothelial cells (HBMEC), which play an essential role as structural and functional components in tumor angiogenesis. "
05/01/2010 - "PMA-mediated cell signaling leading to cyclooxygenase (COX)-2 expression and IkappaB downregulation was also inhibited, further confirming AD4-015 as a cell signaling inhibitor in tumor promoting conditions. "

Related Drugs and Biologics

1.	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)