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octadecyloxyethyl 9-(2-(phosphonomethoxy)ethyl)guanine
structure in first source
Also Known As:
ODE-PMEG
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Purines: 651
Purinones: 2
Hypoxanthines: 1
Guanine: 1793
octadecyloxyethyl 9-(2-(phosphonomethoxy)ethyl)guanine: 1
Organic Chemicals: 133
Organophosphorus Compounds: 300
Organophosphonates: 424
octadecyloxyethyl 9-(2-(phosphonomethoxy)ethyl)guanine: 1
Experts
1.
Aldern, Kathy A
: 1 article (01/2010)
2.
Beadle, James R
: 1 article (01/2010)
3.
Hostetler, Karl Y
: 1 article (01/2010)
4.
Trahan, Julissa
: 1 article (01/2010)
5.
Valiaeva, Nadejda
: 1 article (01/2010)
Related Diseases
1.
Neoplasms (Cancer)
01/01/2010 - "
We compared the effects of ODE-PMEG and ODE-cidofovir (ODE-CDV) in a solid tumor model using Me-180 human cervical cancer cell lines in athymic nude mice.
"
2.
Uterine Cervical Neoplasms (Cancer of the Cervix)
01/01/2010 - "
Intratumoral injection of 25 microg of ODE-PMEG or 100 microg of ODE-CDV daily for 21 days followed by observation for 20-35 days resulted in near-complete disappearance of measurable cervical cancers.
"
01/01/2010 - "
ODE-PMEG had excellent antiproliferative activity in vitro in this panel of human cervical cancers.
"
01/01/2010 - "
We compared the effects of ODE-PMEG and ODE-cidofovir (ODE-CDV) in a solid tumor model using Me-180 human cervical cancer cell lines in athymic nude mice.
"
3.
Uterine Cervical Dysplasia
01/01/2010 - "
ODE-PMEG may be suitable for local or topical treatment of cervical dysplasia.
"
Related Drugs and Biologics
1.
Cidofovir (Vistide)